Advanced glycation end-products (AGEs): Formation, chemistry, classification, receptors, and diseases related to AGEs A Twarda-Clapa, A Olczak, AM Białkowska, M Koziołkiewicz Cells 11 (8), 1312, 2022 | 423 | 2022 |
Ice binding proteins: Diverse biological roles and applications in different types of industry A Białkowska, E Majewska, A Olczak, A Twarda-Clapa Biomolecules 10 (2), 274, 2020 | 86 | 2020 |
2, 3′-Bis (1′ H-indole) heterocycles: New p53/MDM2/MDMX antagonists CG Neochoritis, K Wang, N Estrada-Ortiz, E Herdtweck, K Kubica, ... Bioorganic & medicinal chemistry letters 25 (24), 5661-5666, 2015 | 55 | 2015 |
Rational design and synthesis of 1, 5-disubstituted tetrazoles as potent inhibitors of the MDM2-p53 interaction E Surmiak, CG Neochoritis, B Musielak, A Twarda-Clapa, K Kurpiewska, ... European Journal of Medicinal Chemistry 126, 384-407, 2017 | 53 | 2017 |
Two‐step synthesis of complex artificial macrocyclic compounds R Madhavachary, EMM Abdelraheem, A Rossetti, A Twarda‐Clapa, ... Angewandte Chemie International Edition 56 (36), 10725-10729, 2017 | 49 | 2017 |
Discovery of highly potent p53-MDM2 antagonists and structural basis for anti-acute myeloid leukemia activities Y Huang, S Wolf, B Beck, LM Köhler, K Khoury, GM Popowicz, SK Goda, ... ACS chemical biology 9 (3), 802-811, 2014 | 49 | 2014 |
Artificial macrocycles as potent p53–MDM2 inhibitors N Estrada-Ortiz, CG Neochoritis, A Twarda-Clapa, B Musielak, TA Holak, ... ACS medicinal chemistry letters 8 (10), 1025-1030, 2017 | 48 | 2017 |
Structural characterization of human coronavirus NL63 N protein B Szelazek, W Kabala, K Kus, M Zdzalik, A Twarda-Clapa, P Golik, ... Journal of virology 91 (11), 10.1128/jvi. 02503-16, 2017 | 41 | 2017 |
1, 4, 5-trisubstituted imidazole-based p53–MDM2/MDMX antagonists with aliphatic linkers for conjugation with biological carriers A Twarda-Clapa, S Krzanik, K Kubica, K Guzik, B Labuzek, ... Journal of medicinal chemistry 60 (10), 4234-4244, 2017 | 33 | 2017 |
A unique Mdm2-binding mode of the 3-pyrrolin-2-one-and 2-furanone-based antagonists of the p53-Mdm2 interaction E Surmiak, A Twarda-Clapa, KM Zak, B Musielak, MD Tomala, K Kubica, ... ACS chemical biology 11 (12), 3310-3318, 2016 | 33 | 2016 |
Scaffold hopping via ANCHOR. QUERY: β-lactams as potent p53-MDM2 antagonists S Shaabani, CG Neochoritis, A Twarda-Clapa, B Musielak, TA Holak, ... MedChemComm 8 (5), 1046-1052, 2017 | 30 | 2017 |
Epitope specificity and IgG subclass distribution of autoantibodies to cardiac troponin T Savukoski, A Twarda, S Hellberg, N Ristiniemi, S Wittfooth, J Sinisalo, ... Clinical Chemistry 59 (3), 512-518, 2013 | 30 | 2013 |
Screening of Novel Laccase Producers—Isolation and Characterization of Cold-Adapted Laccase from Kabatiella bupleuri G3 Capable of Synthetic Dye … KM Wiśniewska, A Twarda-Clapa, AM Białkowska Biomolecules 11 (6), 828, 2021 | 20 | 2021 |
Novel Cold-Adapted Recombinant Laccase KbLcc1 from Kabatiella bupleuri G3 IBMiP as a Green Catalyst in Biotransformation KM Wiśniewska, A Twarda-Clapa, AM Białkowska International Journal of Molecular Sciences 22 (17), 9593, 2021 | 18 | 2021 |
Systematic ‘foldamerization’of peptide inhibiting p53-MDM2/X interactions by the incorporation of trans-or cis-2-aminocyclopentanecarboxylic acid residues P Fortuna, A Twarda-Clapa, L Skalniak, K Ożga, TA Holak, Ł Berlicki European Journal of Medicinal Chemistry 208, 112814, 2020 | 17 | 2020 |
A fluorinated indole‐based MDM2 antagonist selectively inhibits the growth of p53wt osteosarcoma cells L Skalniak, A Twarda‐Clapa, CG Neochoritis, E Surmiak, M Machula, ... The FEBS journal 286 (7), 1360-1374, 2019 | 13 | 2019 |
Concise synthesis of macrocycles by multicomponent reactions EMM Abdelraheem, S Khaksar, A Dömling Synthesis 50 (05), 1027-1038, 2018 | 12 | 2018 |
Hitting on the move: targeting intrinsically disordered protein states of the MDM2-p53 interaction CG Neochoritis, J Atmaj, A Twarda-Clapa, E Surmiak, L Skalniak, ... European journal of medicinal chemistry 182, 111588, 2019 | 11 | 2019 |
Crystal structure of the FAS1 domain of the hyaluronic acid receptor stabilin-2 A Twarda-Clapa, B Labuzek, D Krzemien, B Musielak, P Grudnik, G Dubin, ... Biological Crystallography 74 (7), 695-701, 2018 | 6 | 2018 |
NMR fragment-based screening for development of the CD44-binding small molecules M Pustuła, M Czub, B Łabuzek, E Surmiak, M Tomala, A Twarda-Clapa, ... Bioorganic chemistry 82, 284-289, 2019 | 5 | 2019 |