| Packing of apolar side chains enables accurate design of highly stable membrane proteins M Mravic, JL Thomaston, M Tucker, PE Solomon, L Liu, WF DeGrado Science 363 (6434), 1418-1423, 2019 | 122 | 2019 |
| Inhibitors of the M2 proton channel engage and disrupt transmembrane networks of hydrogen-bonded waters JL Thomaston, NF Polizzi, A Konstantinidi, J Wang, A Kolocouris, ... Journal of the American Chemical Society 140 (45), 15219-15226, 2018 | 116 | 2018 |
| High-resolution structures of the M2 channel from influenza A virus reveal dynamic pathways for proton stabilization and transduction JL Thomaston, M Alfonso-Prieto, RA Woldeyes, JS Fraser, ML Klein, ... Proceedings of the National Academy of Sciences 112 (46), 14260-14265, 2015 | 115 | 2015 |
| High-density grids for efficient data collection from multiple crystals EL Baxter, L Aguila, R Alonso-Mori, CO Barnes, CA Bonagura, ... Acta Crystallographica Section D: Structural Biology 72 (1), 2-11, 2016 | 81 | 2016 |
| XFEL structures of the influenza M2 proton channel: Room temperature water networks and insights into proton conduction JL Thomaston, RA Woldeyes, T Nakane, A Yamashita, T Tanaka, ... Proceedings of the National Academy of Sciences 114 (51), 13357-13362, 2017 | 80 | 2017 |
| Crystal structure of the drug‐resistant S31N influenza M2 proton channel JL Thomaston, WF DeGrado Protein Science 25 (8), 1551-1554, 2016 | 46 | 2016 |
| X-ray crystal structures of the influenza M2 proton channel drug-resistant V27A mutant bound to a spiro-adamantyl amine inhibitor reveal the mechanism of adamantane resistance JL Thomaston, A Konstantinidi, L Liu, G Lambrinidis, J Tan, M Caffrey, ... Biochemistry 59 (4), 627-634, 2020 | 38 | 2020 |
| Transient water wires mediate selective proton transport in designed channel proteins HT Kratochvil, LC Watkins, M Mravic, JL Thomaston, JM Nicoludis, ... Nature chemistry 15 (7), 1012-1021, 2023 | 32 | 2023 |
| X-ray crystal structure of the influenza A M2 proton channel S31N mutant in two conformational states: an open and shut case JL Thomaston, Y Wu, N Polizzi, L Liu, J Wang, WF DeGrado Journal of the American Chemical Society 141 (29), 11481-11488, 2019 | 29 | 2019 |
| C‐terminal juxtamembrane region of full‐length M2 protein forms a membrane surface associated amphipathic helix S Huang, B Green, M Thompson, R Chen, J Thomaston, WF DeGrado, ... Protein Science 24 (3), 426-429, 2015 | 26 | 2015 |
| Detection of drug‐induced conformational change of a transmembrane protein in lipid bilayers using site‐directed spin labeling JL Thomaston, PA Nguyen, EC Brown, MA Upshur, J Wang, WF DeGrado, ... Protein Science 22 (1), 65-73, 2013 | 26 | 2013 |
| Rimantadine binds to and inhibits the influenza A M2 proton channel without enantiomeric specificity JL Thomaston, ML Samways, A Konstantinidi, C Ma, Y Hu, ... Biochemistry 60 (32), 2471-2482, 2021 | 21 | 2021 |
| Transient water wires mediate selective proton conduction in designed channel proteins HT Kratochvil, LC Watkins, WF DeGrado bioRxiv, 2022 | 2 | 2022 |
| XFEL structures of the influenza M2 proton channel at 1.4 angstrom: room temperature water networks and insights into proton conduction JL Thomaston, RA Woldeyes, T Nakane, K Koiwai, A Yamashita, ... Acta Crystallographica A-Foundation and Advances 73, A40-A40, 2017 | 1 | 2017 |
| Correction for Thomaston et al., High-resolution structures of the M2 channel from influenza A virus reveal dynamic pathways for proton stabilization and transduction JL Thomaston, M Alfonso-Prieto, RA Woldeyes, JS Fraser, ML Klein, ... Proceedings of the National Academy of Sciences of the United States of …, 2016 | 1 | 2016 |
| STRUCTURAL BASIS OF ADAMANTANE RESISTANCE IN THE INFLUENZA A M2 PROTON CHANNEL J Thomaston, Y Wu, L Liu, J Wang, W DeGrado ACTA CRYSTALLOGRAPHICA A-FOUNDATION AND ADVANCES 75, E140-E140, 2019 | | 2019 |
| Structural characterization of adamantane-resistant mutants of the influenza M2 proton channel JL Thomaston, WF DeGrado ACTA CRYSTALLOGRAPHICA A-FOUNDATION AND ADVANCES 74, A187-A187, 2018 | | 2018 |
| Proton Stabilization and Conduction Pathway in the Matrix Protein M2 HT Kratochvil, JL Thomaston, F Gai, WF DeGrado Biophysical Journal 114 (3), 240a-241a, 2018 | | 2018 |
| Molecular Design and X-Ray Crystal Structure of Engineered Phospholamban Transmembrane Variant M Mravic, J Thomaston, WF DeGrado Biophysical Journal 114 (3), 36a, 2018 | | 2018 |
| X-Ray Crystal Structures of the Influenza a M2 Proton Channel Bound to Amantadine, Rimantadine, and Inhibiting Compounds JL Thomaston, WF DeGrado Biophysical Journal 114 (3), 204a, 2018 | | 2018 |