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Xin D. Gao
Xin D. Gao
Altres nomsDaniel Gao
Post-Doctoral Fellow, Harvard University/Broad Institute
Correu electrònic verificat a broadinstitute.org - Pàgina d'inici
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Programmable deletion, replacement, integration and inversion of large DNA sequences with twin prime editing
AV Anzalone*, XD Gao*, CJ Podracky*, AT Nelson, LW Koblan, ...
Nature biotechnology 40 (5), 731-740, 2022
4132022
Cell type-restricted activity of hnRNPM promotes breast cancer metastasis via regulating alternative splicing
Y Xu, XD Gao, JH Lee, H Huang, H Tan, J Ahn, LM Reinke, ME Peter, ...
Genes & Development, 1191-1203, 2014
2412014
CD44 splice isoform switching determines breast cancer stem cell state
H Zhang, RL Brown, Y Wei, P Zhao, S Liu, X Liu, Y Deng, X Hu, J Zhang, ...
Genes & Development 33 (3-4), 166-179, 2019
2072019
NmeCas9 is an intrinsically high-fidelity genome-editing platform
N Amrani*, XD Gao*, P Liu, A Edraki, A Mir, R Ibraheim, A Gupta, ...
Genome Biology 19 (1), 214, 2018
1432018
C-BERST: defining subnuclear proteomic landscapes at genomic elements with dCas9–APEX2
XD Gao, LC Tu, A Mir, T Rodriguez, Y Ding, J Leszyk, J Dekker, ...
Nature methods 15 (6), 433-436, 2018
1422018
Phage-assisted evolution and protein engineering yield compact, efficient prime editors
JL Doman*, S Pandey*, ME Neugebauer, M An, JR Davis, PB Randolph, ...
Cell 186 (18), 3983-4002. e26, 2023
1252023
Potent Cas9 inhibition in bacterial and human cells by AcrIIC4 and AcrIIC5 Anti-CRISPR proteins
J Lee, A Mir, A Edraki, B Garcia, N Amrani, HE Lou, I Gainetdinov, ...
MBio 9 (6), e02321-18, 2018
982018
Coregulation of alternative splicing by hnRNPM and ESRP1 during EMT
SE Harvey, Y Xu, X Lin, XD Gao, Y Qiu, J Ahn, X Xiao, C Cheng
Rna 24 (10), 1326-1338, 2018
732018
In vivo base editing rescues cone photoreceptors in a mouse model of early-onset inherited retinal degeneration
EH Choi*, S Suh*, AT Foik, H Leinonen, GA Newby, XD Gao, S Banskota, ...
Nature communications 13 (1), 1830, 2022
552022
Adenine Base Editing In Vivo with a Single Adeno-Associated Virus Vector
H Zhang, N Bamidele, P Liu, O Ojelabi, XD Gao, T Rodriguez, H Cheng, ...
GEN biotechnology 1 (3), 285-299, 2022
402022
Efficient site-specific integration of large genes in mammalian cells via continuously evolved recombinases and prime editing
S Pandey*, XD Gao*, NA Krasnow, A McElroy, YA Tao, JE Duby, ...
Nature Biomedical Engineering, 1-18, 2024
322024
Adapting dCas9-APEX2 for subnuclear proteomic profiling
XD Gao, TC Rodríguez, EJ Sontheimer
Methods in Enzymology 616, 365-383, 2019
92019
Prime editing: current advances and therapeutic opportunities in human diseases
Y Fu*, X He*, XD Gao*, F Li, S Ge, Z Yang, X Fan
Science Bulletin, 2023
82023
Methods and compositions for simultaneous editing of both strands of a target double-stranded nucleotide sequence
David R Liu, Andrew Vito Anzalone, Jonathan Ma Levy, Xin Gao, Christopher J ...
US Patent US11912985B2, 2023
8*2023
Twin prime editing mediated exon skipping/reinsertion for restored collagen VII expression in recessive dystrophic epidermolysis bullosa
BJ Steinbeck*, XD Gao*, AN McElroy, S Pandey, JL Doman, MJ Riddle, ...
Journal of Investigative Dermatology, 2024
42024
Methods and compositions for modulating cellular factors to increase prime editing efficiencies
DR Liu, PJ Chen, X Gao
WO Patent App. WO2024138087A2, 2024
2024
Prime editing
DR Liu, AV Anzalone, JM Levy, X Gao, CJ Podracky
nature biotechnology 42 (570), 570, 2024
2024
Crispr base editor
Yan Zhang, David R. Liu, Xin GAO, Kevin T. ZHAO, Zhonggang HOU
WO Patent App. WO2024044329A1, 2024
2024
Methods and compositions for editing a genome with prime editing and a recombinase
David R. Liu, Andrew Vito Anzalone, Jonathan Ma Levy, Xin Gao, Christopher J ...
WO Patent App. WO2023076898A1, 2023
2023
Programmable dna base editing by nme2cas9-deaminase fusion proteins
Erik J Sontheimer, Xin Gao, Aamir Mir, Alireza Edraki, Scot A Wolfe ...
US Patent App. 17/285,440, 2022
2022
En aquests moments el sistema no pot dur a terme l'operació. Torneu-ho a provar més tard.
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