Specific HIV integration sites are linked to clonal expansion and persistence of infected cells F Maldarelli, X Wu, L Su, FR Simonetti, W Shao, S Hill, J Spindler, ... Science 345 (6193), 179-183, 2014 | 945 | 2014 |
A quantitative approach for measuring the reservoir of latent HIV-1 proviruses KM Bruner, Z Wang, FR Simonetti, AM Bender, KJ Kwon, S Sengupta, ... Nature 566 (7742), 120-125, 2019 | 643 | 2019 |
Clonally expanded CD4+ T cells can produce infectious HIV-1 in vivo FR Simonetti, MD Sobolewski, E Fyne, W Shao, J Spindler, J Hattori, ... Proceedings of the National Academy of Sciences 113 (7), 1883-1888, 2016 | 409 | 2016 |
Antigen-driven clonal selection shapes the persistence of HIV-1–infected CD4+ T cells in vivo FR Simonetti, H Zhang, GP Soroosh, J Duan, K Rhodehouse, AL Hill, ... The Journal of clinical investigation 131 (3), 2021 | 149 | 2021 |
Intact proviral DNA assay analysis of large cohorts of people with HIV provides a benchmark for the frequency and composition of persistent proviral DNA FR Simonetti, JA White, C Tumiotto, KD Ritter, M Cai, RT Gandhi, ... Proceedings of the National Academy of Sciences 117 (31), 18692-18700, 2020 | 104 | 2020 |
Different human resting memory CD4+ T cell subsets show similar low inducibility of latent HIV-1 proviruses KJ Kwon, AE Timmons, S Sengupta, FR Simonetti, H Zhang, R Hoh, ... Science translational medicine 12 (528), eaax6795, 2020 | 104 | 2020 |
The landscape of persistent viral genomes in ART-treated SIV, SHIV, and HIV-2 infections AM Bender, FR Simonetti, MR Kumar, EJ Fray, KM Bruner, AE Timmons, ... Cell host & microbe 26 (1), 73-85. e4, 2019 | 95 | 2019 |
Measuring replication competent HIV-1: advances and challenges in defining the latent reservoir Z Wang, FR Simonetti, RF Siliciano, GM Laird Retrovirology 15, 1-9, 2018 | 90 | 2018 |
The forces driving clonal expansion of the HIV-1 latent reservoir R Liu, FR Simonetti, YC Ho Virology journal 17 (1), 4, 2020 | 89 | 2020 |
Clones of infected cells arise early in HIV-infected individuals JM Coffin, DW Wells, JM Zerbato, JD Kuruc, S Guo, BT Luke, JJ Eron, ... JCI insight 4 (12), 2019 | 85 | 2019 |
No evidence of ongoing HIV replication or compartmentalization in tissues during combination antiretroviral therapy: Implications for HIV eradication G Bozzi, FR Simonetti, SA Watters, EM Anderson, M Gouzoulis, ... Science advances 5 (9), eaav2045, 2019 | 83 | 2019 |
Autologous IgG antibodies block outgrowth of a substantial but variable fraction of viruses in the latent reservoir for HIV-1 LN Bertagnolli, J Varriale, S Sweet, J Brockhurst, FR Simonetti, J White, ... Proceedings of the National Academy of Sciences 117 (50), 32066-32077, 2020 | 64 | 2020 |
HIV Infected T Cells Can Proliferate in vivo Without Inducing Expression of the Integrated Provirus A Musick, J Spindler, E Boritz, L Pérez, D Crespo-Vélez, SC Patro, ... Frontiers in microbiology 10, 2204, 2019 | 64 | 2019 |
Complex decay dynamics of HIV virions, intact and defective proviruses, and 2LTR circles following initiation of antiretroviral therapy JA White, FR Simonetti, S Beg, NF McMyn, W Dai, N Bachmann, J Lai, ... Proceedings of the National Academy of Sciences 119 (6), e2120326119, 2022 | 63 | 2022 |
The role of CD32 during HIV-1 infection LN Bertagnolli, JA White, FR Simonetti, SA Beg, J Lai, C Tomescu, ... Nature 561 (7723), E17-E19, 2018 | 63 | 2018 |
Clonally expanded HIV-1 proviruses with 5′-leader defects can give rise to nonsuppressible residual viremia JA White, F Wu, S Yasin, M Moskovljevic, J Varriale, F Dragoni, ... The Journal of clinical investigation 133 (6), 2023 | 59 | 2023 |
The latent reservoir of inducible, infectious HIV-1 does not decrease despite decades of antiretroviral therapy NF McMyn, J Varriale, EJ Fray, C Zitzmann, H MacLeod, J Lai, A Singhal, ... The Journal of Clinical Investigation 133 (17), 2023 | 57 | 2023 |
Origin, evolution, and phylogeography of recent epidemic CHIKV strains AL Presti, M Ciccozzi, E Cella, A Lai, FR Simonetti, M Galli, G Zehender, ... Infection, Genetics and Evolution 12 (2), 392-398, 2012 | 54 | 2012 |
Dynamic shifts in the HIV proviral landscape during long term combination antiretroviral therapy: implications for persistence and control of HIV infections EM Anderson, FR Simonetti, RJ Gorelick, S Hill, MA Gouzoulis, J Bell, ... Viruses 12 (2), 136, 2020 | 41 | 2020 |
Measuring the latent reservoir for HIV-1: Quantification bias in near full-length genome sequencing methods JA White, JT Kufera, N Bachmann, W Dai, FR Simonetti, C Armstrong, ... PLoS pathogens 18 (9), e1010845, 2022 | 40 | 2022 |