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Mélanie Gomez
Mélanie Gomez
CarMeN-IRIS team
Correu electrònic verificat a univ-lyon1.fr
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Sphingosine-1-phosphate produced by sphingosine kinase 2 in mitochondria interacts with prohibitin 2 to regulate complex IV assembly and respiration
GM Strub, M Paillard, J Liang, L Gomez, JC Allegood, NC Hait, ...
The FASEB Journal 25 (2), 600, 2011
4192011
Inhibition of GSK3β by postconditioning is required to prevent opening of the mitochondrial permeability transition pore during reperfusion
L Gomez, M Paillard, H Thibault, G Derumeaux, M Ovize
Circulation 117 (21), 2761-2768, 2008
4162008
Depressing mitochondria-reticulum interactions protects cardiomyocytes from lethal hypoxia-reoxygenation injury
M Paillard, E Tubbs, PA Thiebaut, L Gomez, J Fauconnier, ...
Circulation 128 (14), 1555-1565, 2013
2762013
MICU1 regulation of mitochondrial Ca2+ uptake dictates survival and tissue regeneration
AN Antony, M Paillard, C Moffat, E Juskeviciute, J Correnti, B Bolon, ...
Nature communications 7 (1), 10955, 2016
2102016
Tissue-specific mitochondrial decoding of cytoplasmic Ca2+ signals is controlled by the stoichiometry of MICU1/2 and MCU
M Paillard, G Csordás, G Szanda, T Golenár, V Debattisti, A Bartok, ...
Cell reports 18 (10), 2291-2300, 2017
2042017
Mitochondrial fusion dynamics is robust in the heart and depends on calcium oscillations and contractile activity
V Eisner, RR Cupo, E Gao, G Csordás, WS Slovinsky, M Paillard, ...
Proceedings of the National Academy of Sciences 114 (5), E859-E868, 2017
1642017
Disruption of calcium transfer from ER to mitochondria links alterations of mitochondria-associated ER membrane integrity to hepatic insulin resistance
J Rieusset, J Fauconnier, M Paillard, E Belaidi, E Tubbs, MA Chauvin, ...
Diabetologia 59, 614-623, 2016
1542016
Inhibition of mitochondrial permeability transition to prevent the post-cardiac arrest syndrome: a pre-clinical study
M Cour, J Loufouat, M Paillard, L Augeul, J Goudable, M Ovize, L Argaud
European heart journal 32 (2), 226-235, 2011
1292011
MICU1 interacts with the D-ring of the MCU pore to control its Ca2+ flux and sensitivity to Ru360
M Paillard, G Csordás, KT Huang, P Várnai, SK Joseph, G Hajnóczky
Molecular cell 72 (4), 778-785. e3, 2018
1222018
Activation of mitochondrial μ-calpain increases AIF cleavage in cardiac mitochondria during ischemia–reperfusion
Q Chen, M Paillard, L Gomez, T Ross, Y Hu, A Xu, EJ Lesnefsky
Biochemical and biophysical research communications 415 (4), 533-538, 2011
1132011
The SR/ER-mitochondria calcium crosstalk is regulated by GSK3β during reperfusion injury
L Gomez, PA Thiebaut, M Paillard, S Ducreux, M Abrial, C Crola Da Silva, ...
Cell Death & Differentiation 23 (2), 313-322, 2016
1102016
Reduced reticulum–mitochondria Ca2+ transfer is an early and reversible trigger of mitochondrial dysfunctions in diabetic cardiomyopathy
M Dia, L Gomez, H Thibault, N Tessier, C Leon, C Chouabe, S Ducreux, ...
Basic research in cardiology 115, 1-21, 2020
1082020
Postconditioning inhibits mPTP opening independent of oxidative phosphorylation and membrane potential
M Paillard, L Gomez, L Augeul, J Loufouat, EJ Lesnefsky, M Ovize
Journal of molecular and cellular cardiology 46 (6), 902-909, 2009
952009
A novel role for mitochondrial sphingosine-1-phosphate produced by sphingosine kinase-2 in PTP-mediated cell survival during cardioprotection
L Gomez, M Paillard, M Price, Q Chen, G Teixeira, S Spiegel, ...
Basic research in cardiology 106, 1341-1353, 2011
912011
Postconditioning modulates ischemia-damaged mitochondria during reperfusion
Q Chen, M Paillard, L Gomez, H Li, Y Hu, EJ Lesnefsky
Journal of cardiovascular pharmacology 59 (1), 101-108, 2012
562012
Reliance of ER–mitochondrial calcium signaling on mitochondrial EF-hand Ca2+ binding proteins: Miros, MICUs, LETM1 and solute carriers
G Hajnóczky, D Booth, G Csordás, V Debattisti, T Golenár, S Naghdi, ...
Current opinion in cell biology 29, 133-141, 2014
542014
Pharmacological inhibition of the mitochondrial Ca2+ uniporter: relevance for pathophysiology and human therapy
K Márta, P Hasan, M Rodríguez-Prados, M Paillard, G Hajnóczky
Journal of molecular and cellular cardiology 151, 135-144, 2021
502021
4TM-TRPM8 channels are new gatekeepers of the ER-mitochondria Ca2+ transfer
G Bidaux, D Gordienko, G Shapovalov, V Farfariello, A Borowiec, ...
Biochimica et Biophysica Acta (BBA)-Molecular Cell Research 1865 (7), 981-994, 2018
432018
Uncontrolled mitochondrial calcium uptake underlies the pathogenesis of neurodegeneration in MICU1-deficient mice and patients
R Singh, A Bartok, M Paillard, A Tyburski, M Elliott, G Hajnóczky
Science advances 8 (11), eabj4716, 2022
332022
A novel class of cardioprotective small-molecule PTP inhibitors
S Antonucci, M Di Sante, J Sileikyte, J Deveraux, T Bauer, MJ Bround, ...
Pharmacological research 151, 104548, 2020
312020
En aquests moments el sistema no pot dur a terme l'operació. Torneu-ho a provar més tard.
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