Sphingosine-1-phosphate produced by sphingosine kinase 2 in mitochondria interacts with prohibitin 2 to regulate complex IV assembly and respiration GM Strub, M Paillard, J Liang, L Gomez, JC Allegood, NC Hait, ... The FASEB Journal 25 (2), 600, 2011 | 419 | 2011 |
Inhibition of GSK3β by postconditioning is required to prevent opening of the mitochondrial permeability transition pore during reperfusion L Gomez, M Paillard, H Thibault, G Derumeaux, M Ovize Circulation 117 (21), 2761-2768, 2008 | 416 | 2008 |
Depressing mitochondria-reticulum interactions protects cardiomyocytes from lethal hypoxia-reoxygenation injury M Paillard, E Tubbs, PA Thiebaut, L Gomez, J Fauconnier, ... Circulation 128 (14), 1555-1565, 2013 | 276 | 2013 |
MICU1 regulation of mitochondrial Ca2+ uptake dictates survival and tissue regeneration AN Antony, M Paillard, C Moffat, E Juskeviciute, J Correnti, B Bolon, ... Nature communications 7 (1), 10955, 2016 | 210 | 2016 |
Tissue-specific mitochondrial decoding of cytoplasmic Ca2+ signals is controlled by the stoichiometry of MICU1/2 and MCU M Paillard, G Csordás, G Szanda, T Golenár, V Debattisti, A Bartok, ... Cell reports 18 (10), 2291-2300, 2017 | 204 | 2017 |
Mitochondrial fusion dynamics is robust in the heart and depends on calcium oscillations and contractile activity V Eisner, RR Cupo, E Gao, G Csordás, WS Slovinsky, M Paillard, ... Proceedings of the National Academy of Sciences 114 (5), E859-E868, 2017 | 164 | 2017 |
Disruption of calcium transfer from ER to mitochondria links alterations of mitochondria-associated ER membrane integrity to hepatic insulin resistance J Rieusset, J Fauconnier, M Paillard, E Belaidi, E Tubbs, MA Chauvin, ... Diabetologia 59, 614-623, 2016 | 154 | 2016 |
Inhibition of mitochondrial permeability transition to prevent the post-cardiac arrest syndrome: a pre-clinical study M Cour, J Loufouat, M Paillard, L Augeul, J Goudable, M Ovize, L Argaud European heart journal 32 (2), 226-235, 2011 | 129 | 2011 |
MICU1 interacts with the D-ring of the MCU pore to control its Ca2+ flux and sensitivity to Ru360 M Paillard, G Csordás, KT Huang, P Várnai, SK Joseph, G Hajnóczky Molecular cell 72 (4), 778-785. e3, 2018 | 122 | 2018 |
Activation of mitochondrial μ-calpain increases AIF cleavage in cardiac mitochondria during ischemia–reperfusion Q Chen, M Paillard, L Gomez, T Ross, Y Hu, A Xu, EJ Lesnefsky Biochemical and biophysical research communications 415 (4), 533-538, 2011 | 113 | 2011 |
The SR/ER-mitochondria calcium crosstalk is regulated by GSK3β during reperfusion injury L Gomez, PA Thiebaut, M Paillard, S Ducreux, M Abrial, C Crola Da Silva, ... Cell Death & Differentiation 23 (2), 313-322, 2016 | 110 | 2016 |
Reduced reticulum–mitochondria Ca2+ transfer is an early and reversible trigger of mitochondrial dysfunctions in diabetic cardiomyopathy M Dia, L Gomez, H Thibault, N Tessier, C Leon, C Chouabe, S Ducreux, ... Basic research in cardiology 115, 1-21, 2020 | 108 | 2020 |
Postconditioning inhibits mPTP opening independent of oxidative phosphorylation and membrane potential M Paillard, L Gomez, L Augeul, J Loufouat, EJ Lesnefsky, M Ovize Journal of molecular and cellular cardiology 46 (6), 902-909, 2009 | 95 | 2009 |
A novel role for mitochondrial sphingosine-1-phosphate produced by sphingosine kinase-2 in PTP-mediated cell survival during cardioprotection L Gomez, M Paillard, M Price, Q Chen, G Teixeira, S Spiegel, ... Basic research in cardiology 106, 1341-1353, 2011 | 91 | 2011 |
Postconditioning modulates ischemia-damaged mitochondria during reperfusion Q Chen, M Paillard, L Gomez, H Li, Y Hu, EJ Lesnefsky Journal of cardiovascular pharmacology 59 (1), 101-108, 2012 | 56 | 2012 |
Reliance of ER–mitochondrial calcium signaling on mitochondrial EF-hand Ca2+ binding proteins: Miros, MICUs, LETM1 and solute carriers G Hajnóczky, D Booth, G Csordás, V Debattisti, T Golenár, S Naghdi, ... Current opinion in cell biology 29, 133-141, 2014 | 54 | 2014 |
Pharmacological inhibition of the mitochondrial Ca2+ uniporter: relevance for pathophysiology and human therapy K Márta, P Hasan, M Rodríguez-Prados, M Paillard, G Hajnóczky Journal of molecular and cellular cardiology 151, 135-144, 2021 | 50 | 2021 |
4TM-TRPM8 channels are new gatekeepers of the ER-mitochondria Ca2+ transfer G Bidaux, D Gordienko, G Shapovalov, V Farfariello, A Borowiec, ... Biochimica et Biophysica Acta (BBA)-Molecular Cell Research 1865 (7), 981-994, 2018 | 43 | 2018 |
Uncontrolled mitochondrial calcium uptake underlies the pathogenesis of neurodegeneration in MICU1-deficient mice and patients R Singh, A Bartok, M Paillard, A Tyburski, M Elliott, G Hajnóczky Science advances 8 (11), eabj4716, 2022 | 33 | 2022 |
A novel class of cardioprotective small-molecule PTP inhibitors S Antonucci, M Di Sante, J Sileikyte, J Deveraux, T Bauer, MJ Bround, ... Pharmacological research 151, 104548, 2020 | 31 | 2020 |