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Karen G. Fleming
Karen G. Fleming
Professor of Biophysics, Johns Hopkins University
Correu electrònic verificat a jhu.edu
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Side-chain hydrophobicity scale derived from transmembrane protein folding into lipid bilayers
CP Moon, KG Fleming
Proceedings of the National Academy of Sciences 108 (25), 10174-10177, 2011
3562011
What makes a protein a protein? Hydrophobic core designs that specify stability and structural properties
M Munson, S Balasubramanian, KG Fleming, AD Nagi, R O'Brien, ...
Protein Science 5 (8), 1584-1593, 1996
3051996
The effect of point mutations on the free energy of transmembrane α-helix dimerization
KG Fleming, AL Ackerman, DM Engelman
Journal of molecular biology 272 (2), 266-275, 1997
2971997
β-Barrel proteins that reside in the Escherichia coli outer membrane in vivo demonstrate varied folding behavior in vitro
NK Burgess, TP Dao, AM Stanley, KG Fleming
Journal of Biological Chemistry 283 (39), 26748-26758, 2008
2782008
Specificity in transmembrane helix–helix interactions can define a hierarchy of stability for sequence variants
KG Fleming, DM Engelman
Proceedings of the National Academy of Sciences 98 (25), 14340-14344, 2001
2272001
Outer membrane β-barrel protein folding is physically controlled by periplasmic lipid head groups and BamA
D Gessmann, YH Chung, EJ Danoff, AM Plummer, CW Sandlin, ...
Proceedings of the National Academy of Sciences 111 (16), 5878-5883, 2014
2082014
Binding of polyubiquitin chains to ubiquitin-associated (UBA) domains of HHR23A
S Raasi, I Orlov, KG Fleming, CM Pickart
Journal of molecular biology 341 (5), 1367-1379, 2004
1982004
HullRad: fast calculations of folded and disordered protein and nucleic acid hydrodynamic properties
PJ Fleming, KG Fleming
Biophysical journal 114 (4), 856-869, 2018
1852018
E. coli outer membrane and interactions with OmpLA
EL Wu, PJ Fleming, MS Yeom, G Widmalm, JB Klauda, KG Fleming, W Im
Biophysical journal 106 (11), 2493-2502, 2014
1752014
Genetically encoded biosensors for visualizing live-cell biochemical activity at super-resolution
GCH Mo, B Ross, F Hertel, P Manna, X Yang, E Greenwald, C Booth, ...
Nature methods 14 (4), 427-434, 2017
1652017
Standardizing the free energy change of transmembrane helix–helix interactions
KG Fleming
Journal of molecular biology 323 (3), 563-571, 2002
1402002
The effects of salt on the TATA binding protein-DNA interaction from a hyperthermophilic archaeon
R O’Brien, B DeDecker, KG Fleming, PB Sigler, JE Ladbury
Journal of molecular biology 279 (1), 117-125, 1998
1391998
Sequence context modulates the stability of a GxxxG-mediated transmembrane helix–helix dimer
AK Doura, FJ Kobus, L Dubrovsky, E Hibbard, KG Fleming
Journal of molecular biology 341 (4), 991-998, 2004
1312004
Membrane protein thermodynamic stability may serve as the energy sink for sorting in the periplasm
CP Moon, NR Zaccai, PJ Fleming, D Gessmann, KG Fleming
Proceedings of the National Academy of Sciences 110 (11), 4285-4290, 2013
1292013
A zinc-binding domain involved in the dimerization of RAG1
KK Rodgers, Z Bu, KG Fleming, DG Schatz, DM Engelman, JE Coleman
Journal of molecular biology 260 (1), 70-84, 1996
1291996
Complex interactions at the helix–helix interface stabilize the glycophorin A transmembrane dimer
AK Doura, KG Fleming
Journal of molecular biology 343 (5), 1487-1497, 2004
1242004
De novo design of transmembrane β barrels
AA Vorobieva, P White, B Liang, JE Horne, AK Bera, CM Chow, S Gerben, ...
Science 371 (6531), eabc8182, 2021
1212021
The process of folding proteins into membranes: challenges and progress
AM Stanley, KG Fleming
Archives of biochemistry and biophysics 469 (1), 46-66, 2008
1202008
Structure of the lethal phage pinhole
T Pang, CG Savva, KG Fleming, DK Struck, R Young
Proceedings of the National Academy of Sciences 106 (45), 18966-18971, 2009
1162009
A revised model for the oligomeric state of the N-ethylmaleimide-sensitive fusion protein, NSF
KG Fleming, TM Hohl, CY Richard, SA Muller, B Wolpensinger, A Engel, ...
Journal of Biological Chemistry 273 (25), 15675-15681, 1998
1131998
En aquests moments el sistema no pot dur a terme l'operació. Torneu-ho a provar més tard.
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