Potent antimyeloma activity of the novel bromodomain inhibitors I-BET151 and I-BET762 A Chaidos, V Caputo, K Gouvedenou, B Liu, I Marigo, MS Chaudhry, ... Blood, The Journal of the American Society of Hematology 123 (5), 697-705, 2014 | 232 | 2014 |
Inhibition of bromodomain and extra-terminal proteins (BET) as a potential therapeutic approach in haematological malignancies: emerging preclinical and clinical evidence A Chaidos, V Caputo, A Karadimitris Therapeutic advances in hematology 6 (3), 128-141, 2015 | 188 | 2015 |
Single-cell profiling of human megakaryocyte-erythroid progenitors identifies distinct megakaryocyte and erythroid differentiation pathways B Psaila, N Barkas, D Iskander, A Roy, S Anderson, N Ashley, VS Caputo, ... Genome biology 17, 1-19, 2016 | 172 | 2016 |
Enhanced anti-lymphoma activity of CAR19-iNKT cells underpinned by dual CD19 and CD1d targeting A Rotolo, VS Caputo, M Holubova, N Baxan, O Dubois, MS Chaudhry, ... Cancer Cell 34 (4), 596-610. e11, 2018 | 145 | 2018 |
Single-cell profiling of human bone marrow progenitors reveals mechanisms of failing erythropoiesis in Diamond-Blackfan anemia D Iskander, G Wang, EF Heuston, C Christodoulidou, B Psaila, ... Science translational medicine 13 (610), eabf0113, 2021 | 48 | 2021 |
The coordinated action of VCP/p97 and GCN2 regulates cancer cell metabolism and proteostasis during nutrient limitation K Parzych, P Saavedra-García, GN Valbuena, HA Al-Sadah, ... Oncogene 38 (17), 3216-3231, 2019 | 43 | 2019 |
Systems medicine dissection of chr1q-amp reveals a novel PBX1-FOXM1 axis for targeted therapy in multiple myeloma N Trasanidis, A Katsarou, K Ponnusamy, YA Shen, IV Kostopoulos, ... Blood, The Journal of the American Society of Hematology 139 (13), 1939-1953, 2022 | 30 | 2022 |
Systems level profiling of chemotherapy-induced stress resolution in cancer cells reveals druggable trade-offs P Saavedra-García, M Roman-Trufero, HA Al-Sadah, K Blighe, ... Proceedings of the National Academy of Sciences 118 (17), e2018229118, 2021 | 30 | 2021 |
The prospects and promise of chimeric antigen receptor immunotherapy in multiple myeloma A Rotolo, V Caputo, A Karadimitris British Journal of Haematology 173 (3), 350-364, 2016 | 30 | 2016 |
Transcriptional and epigenetic basis for restoration of G6PD enzymatic activity in human G6PD-deficient cells K Makarona, VS Caputo, JR Costa, B Liu, D O’Connor, D Iskander, ... Blood, The Journal of the American Society of Hematology 124 (1), 134-141, 2014 | 30 | 2014 |
Chromatin-based, in cis and in trans regulatory rewiring underpins distinct oncogenic transcriptomes in multiple myeloma J Alvarez-Benayas, N Trasanidis, A Katsarou, K Ponnusamy, A Chaidos, ... Nature communications 12 (1), 5450, 2021 | 29 | 2021 |
The innate sensor ZBP1-IRF3 axis regulates cell proliferation in multiple myeloma K Ponnusamy, MM Tzioni, M Begum, ME Robinson, VS Caputo, ... Haematologica 107 (3), 721, 2021 | 27 | 2021 |
Role of polymorphisms of NKG2D receptor and its ligands in acute myeloid leukemia and human stem cell transplantation A Machuldova, M Holubova, VS Caputo, M Cedikova, P Jindra, ... Frontiers in Immunology 12, 651751, 2021 | 19 | 2021 |
Specific Targeted Integration of Kanamycin Resistance-Associated Nonselectable DNA in the Genome of the Yeast Saccharomyces cerevisiae SK Waghmare, V Caputo, S Radovic, CV Bruschi Biotechniques 34 (5), 1024-1033, 2003 | 18 | 2003 |
Brd2/4 and Myc regulate alternative cell lineage programmes during early osteoclast differentiation in vitro VS Caputo, N Trasanidis, X Xiao, ME Robinson, A Katsarou, ... IScience 24 (1), 2021 | 17 | 2021 |
Myeloma propagating cells, drug resistance and relapse A Karadimitris, A Chaidos, V Caputo, K Goudevenou, K Ponnusamy, ... Stem Cells 33 (11), 3205-3211, 2015 | 13 | 2015 |
Mechanism of Polycomb recruitment to CpG islands revealed by inherited disease-associated mutation VS Caputo, JR Costa, K Makarona, E Georgiou, DM Layton, I Roberts, ... Human molecular genetics 22 (16), 3187-3194, 2013 | 10 | 2013 |
Taspase1 processing alters TFIIA cofactor properties in the regulation of TFIID B Malecová, VS Caputo, DF Lee, JJ Hsieh, T Oelgeschläger Transcription 6 (2), 21-32, 2015 | 7 | 2015 |
Cell-type–specific transcriptional regulation of PIGM underpins the divergent hematologic phenotype in inherited GPl deficiency JR Costa, VS Caputo, K Makarona, DM Layton, IAG Roberts, AM Almeida, ... Blood, The Journal of the American Society of Hematology 124 (20), 3151-3154, 2014 | 7 | 2014 |
Dynamic changes of inhibitory killer-immunoglobulin-like receptors on NK cells after allogeneic hematopoietic stem cell transplantation: an initial study T Dekojová, L Houdová, J Fatka, P Pitule, P Ostašov, VS Caputo, ... Journal of Clinical Medicine 9 (11), 3502, 2020 | 5 | 2020 |