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Dr. Kellie Machlus
Dr. Kellie Machlus
Harvard Medical School
Correu electrònic verificat a childrens.harvard.edu - Pàgina d'inici
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The incredible journey: From megakaryocyte development to platelet formation
KR Machlus, JE Italiano Jr
Journal of Cell Biology 201 (6), 785-796, 2013
10232013
Procoagulant activity in hemostasis and thrombosis: Virchow's triad revisited
AS Wolberg, MM Aleman, K Leiderman, KR Machlus
Anesthesia & Analgesia 114 (2), 275-285, 2012
4422012
Interpreting the developmental dance of the megakaryocyte: a review of the cellular and molecular processes mediating platelet formation
KR Machlus, JN Thon, JE Italiano Jr
British journal of haematology 165 (2), 227-236, 2014
3192014
New insights into the differentiation of megakaryocytes from hematopoietic progenitors
LJ Noetzli, SL French, KR Machlus
Arteriosclerosis, thrombosis, and vascular biology 39 (7), 1288-1300, 2019
2712019
Scalable generation of universal platelets from human induced pluripotent stem cells
Q Feng, N Shabrani, JN Thon, H Huo, A Thiel, KR Machlus, K Kim, ...
Stem cell reports 3 (5), 817-831, 2014
2632014
Causal relationship between hyperfibrinogenemia, thrombosis, and resistance to thrombolysis in mice
KR Machlus, JC Cardenas, FC Church, AS Wolberg
Blood, The Journal of the American Society of Hematology 117 (18), 4953-4963, 2011
2512011
T granules in human platelets function in TLR9 organization and signaling
JN Thon, CG Peters, KR Machlus, R Aslam, J Rowley, H Macleod, ...
Journal of Cell Biology 198 (4), 561-574, 2012
2452012
Platelet bioreactor-on-a-chip
JN Thon, L Mazutis, S Wu, JL Sylman, A Ehrlicher, KR Machlus, Q Feng, ...
Blood, The Journal of the American Society of Hematology 124 (12), 1857-1867, 2014
2402014
Platelets release pathogenic serotonin and return to circulation after immune complex-mediated sequestration
N Cloutier, I Allaeys, G Marcoux, KR Machlus, B Mailhot, A Zufferey, ...
Proceedings of the National Academy of Sciences 115 (7), E1550-E1559, 2018
2292018
Platelet extracellular vesicles: beyond the blood
F Puhm, E Boilard, KR Machlus
Arteriosclerosis, thrombosis, and vascular biology 41 (1), 87-96, 2021
2132021
Anticoagulation inhibits tumor cell–mediated release of platelet angiogenic proteins and diminishes platelet angiogenic response
EM Battinelli, BA Markens, RA Kulenthirarajan, KR Machlus, ...
Blood, The Journal of the American Society of Hematology 123 (1), 101-112, 2014
1422014
Mature murine megakaryocytes present antigen-MHC class I molecules to T cells and transfer them to platelets
A Zufferey, ER Speck, KR Machlus, R Aslam, L Guo, MJ McVey, M Kim, ...
Blood advances 1 (20), 1773-1785, 2017
1342017
Effects of tissue factor, thrombomodulin and elevated clotting factor levels on thrombin generation in the calibrated automated thrombogram
KR Machlus, EA Colby, JR Wu, GG Koch, NS Key, AS Wolberg
Thrombosis and haemostasis 102 (11), 936-944, 2009
1212009
CCL5 derived from platelets increases megakaryocyte proplatelet formation
KR Machlus, KE Johnson, R Kulenthirarajan, JA Forward, MD Tippy, ...
Blood, The Journal of the American Society of Hematology 127 (7), 921-926, 2016
1202016
Megakaryocyte emperipolesis mediates membrane transfer from intracytoplasmic neutrophils to platelets
P Cunin, R Bouslama, KR Machlus, M Martínez-Bonet, PY Lee, A Wactor, ...
Elife 8, e44031, 2019
1052019
Platelet-derived extracellular vesicles infiltrate and modify the bone marrow during inflammation
SL French, KR Butov, I Allaeys, J Canas, G Morad, P Davenport, ...
Blood Advances 4 (13), 3011-3023, 2020
1002020
Human bone marrow organoids for disease modeling, discovery, and validation of therapeutic targets in hematologic malignancies
AO Khan, A Rodriguez-Romera, JS Reyat, AA Olijnik, M Colombo, ...
Cancer discovery 13 (2), 364-385, 2023
902023
Proteasome function is required for platelet production
DS Shi, MCP Smith, RA Campbell, PW Zimmerman, ZB Franks, ...
The Journal of clinical investigation 124 (9), 3757-3766, 2014
812014
Detection of endogenous tissue factor levels in plasma using the calibrated automated thrombogram assay
V Ollivier, J Wang, D Manly, KR Machlus, AS Wolberg, M Jandrot-Perrus, ...
Thrombosis research 125 (1), 90-96, 2010
782010
Reduced contraction of blood clots in venous thromboembolism is a potential thrombogenic and embologenic mechanism
AD Peshkova, DV Malyasyov, RA Bredikhin, G Le Minh, IA Andrianova, ...
TH Open 2 (01), e104-e115, 2018
772018
En aquests moments el sistema no pot dur a terme l'operació. Torneu-ho a provar més tard.
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