| Transcriptional silencing of transposons by Piwi and maelstrom and its impact on chromatin state and gene expression G Sienski, D Dönertas, J Brennecke Cell 151 (5), 964-980, 2012 | 695 | 2012 |
| The Rhino-Deadlock-Cutoff Complex Licenses Noncanonical Transcription of Dual-Strand piRNA Clusters in Drosophila F Mohn, G Sienski, D Handler, J Brennecke Cell 157 (6), 1364-1379, 2014 | 418 | 2014 |
| APOE4 disrupts intracellular lipid homeostasis in human iPSC-derived glia G Sienski, P Narayan, JM Bonner, N Kory, S Boland, AA Arczewska, ... Science translational medicine 13 (583), eaaz4564, 2021 | 269 | 2021 |
| Silencio/CG9754 connects the Piwi–piRNA complex to the cellular heterochromatin machinery G Sienski, J Batki, KA Senti, D Dönertas, L Tirian, K Meixner, J Brennecke Genes & development 29 (21), 2258-2271, 2015 | 183 | 2015 |
| Drosophila Gtsf1 is an essential component of the Piwi-mediated transcriptional silencing complex D Dönertas, G Sienski, J Brennecke Genes & development 27 (15), 1693-1705, 2013 | 168 | 2013 |
| Efficient CRISPR/Cas9 plasmids for rapid and versatile genome editing in Drosophila J Gokcezade, G Sienski, P Duchek G3: Genes, Genomes, Genetics 4 (11), 2279-2282, 2014 | 135 | 2014 |
| Noncanonical role of the 9-1-1 clamp in the error-free DNA damage tolerance pathway GI Karras, M Fumasoni, G Sienski, F Vanoli, D Branzei, S Jentsch Molecular cell 49 (3), 536-546, 2013 | 113 | 2013 |
| PICALM rescues endocytic defects caused by the Alzheimer’s disease risk factor APOE4 P Narayan, G Sienski, JM Bonner, YT Lin, J Seo, V Baru, A Haque, B Milo, ... Cell reports 33 (1), 2020 | 72 | 2020 |
| Harnessing DSB repair to promote efficient homology-dependent and-independent prime editing M Peterka, N Akrap, S Li, S Wimberger, PP Hsieh, D Degtev, B Bestas, ... Nature Communications 13 (1), 1240, 2022 | 38 | 2022 |
| Universal toxin-based selection for precise genome engineering in human cells S Li, N Akrap, S Cerboni, MJ Porritt, S Wimberger, A Lundin, C Möller, ... Nature communications 12 (1), 497, 2021 | 37 | 2021 |
| Panoramix SUMOylation on chromatin connects the piRNA pathway to the cellular heterochromatin machinery VI Andreev, C Yu, J Wang, J Schnabl, L Tirian, M Gehre, D Handler, ... Nature Structural & Molecular Biology 29 (2), 130-142, 2022 | 27 | 2022 |
| The role of miR-17-92 in the miRegulatory landscape of Ewing sarcoma R Schwentner, D Herrero-Martin, MO Kauer, CN Mutz, AM Katschnig, ... Oncotarget 8 (7), 10980, 2017 | 17 | 2017 |
| A Type II-B Cas9 nuclease with minimized off-targets and reduced chromosomal translocations in vivo B Bestas, S Wimberger, D Degtev, A Madsen, AK Rottner, F Karlsson, ... Nature Communications 14 (1), 5474, 2023 | 9 | 2023 |
| TLCD1 and TLCD2 regulate cellular phosphatidylethanolamine composition and promote the progression of non-alcoholic steatohepatitis K Petkevicius, H Palmgren, MS Glover, A Ahnmark, AC Andréasson, ... Nature Communications 13 (1), 6020, 2022 | 9 | 2022 |
| SLC25A38 is required for mitochondrial pyridoxal 5’-phosphate (PLP) accumulation IA Pena, JS Shi, SM Chang, J Yang, S Block, CH Adelmann, HR Keys, ... Nature Communications 16 (1), 978, 2025 | 1 | 2025 |
| Optimized prime editing of the Alzheimer’s disease-associated APOE4 mutation AK Rottner, A Lundin, S Li, M Firth, M Maresca, G Sienski Stem Cell Reports, 2024 | | 2024 |
| CA S9 EFFECTOR PROTEINS WITH ENHANCED STABILITY G Sienski, M Maresca US Patent App. 18/559,598, 2024 | | 2024 |
| Engineered PsCas9 enables therapeutic genome editing in mouse liver with lipid nanoparticles D Degtev, J Bravo, A Emmanouilidi, A Zdravković, OK Choong, ... Nature Communications 15 (1), 9173, 2024 | | 2024 |
| The use of choline supplementation as therapy for apoe4-related disorders LH Tsai, YT Lin, J Bonner, P Narayan, G Sienski US Patent App. 17/318,921, 2021 | | 2021 |