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Activation of c-Jun N-terminal kinase in bacterial lipopolysaccharide-stimulated macrophages. J Hambleton, SL Weinstein, L Lem, AL DeFranco Proceedings of the National Academy of Sciences 93 (7), 2774-2778, 1996 | 602 | 1996 |
Characterization of the B lymphocyte populations in Lyn-deficient mice and the role of Lyn in signal initiation and down-regulation VWF Chan, F Meng, P Soriano, AL DeFranco, CA Lowell Immunity 7 (1), 69-81, 1997 | 567 | 1997 |
Bacterial lipopolysaccharide induces tyrosine phosphorylation and activation of mitogen-activated protein kinases in macrophages. SL Weinstein, JS Sanghera, K Lemke, AL DeFranco, SL Pelech Journal of Biological Chemistry 267 (21), 14955-14962, 1992 | 476 | 1992 |
Stimulation of protein tyrosine phosphorylation by the B-lymphocyte antigen receptor MR Gold, DA Law, AL DeFranco Nature 345 (6278), 810-813, 1990 | 446 | 1990 |
Bacterial lipopolysaccharide stimulates protein tyrosine phosphorylation in macrophages. SL Weinstein, MR Gold, AL DeFranco Proceedings of the National Academy of Sciences 88 (10), 4148-4152, 1991 | 428 | 1991 |
The complexity of signaling pathways activated by the BCR AL DeFranco Current opinion in immunology 9 (3), 296-308, 1997 | 427 | 1997 |
Toll-like receptors activate innate and adaptive immunity by using dendritic cell-intrinsic and-extrinsic mechanisms B Hou, B Reizis, AL DeFranco Immunity 29 (2), 272-282, 2008 | 425 | 2008 |
Frequency of B lymphocytes responsive to anti-immunoglobulin. AL Defranco, ES Raveche, R Asofsky, WE Paul The Journal of experimental medicine 155 (5), 1523-1536, 1982 | 384 | 1982 |
γδ intraepithelial lymphocytes are essential mediators of host–microbial homeostasis at the intestinal mucosal surface AS Ismail, KM Severson, S Vaishnava, CL Behrendt, X Yu, JL Benjamin, ... Proceedings of the National Academy of Sciences 108 (21), 8743-8748, 2011 | 350 | 2011 |
Fcγ receptor–mediated phagocytosis in macrophages lacking the Src family tyrosine kinases Hck, Fgr, and Lyn CJ Fitzer-Attas, M Lowry, MT Crowley, AJ Finn, F Meng, AL DeFranco, ... The Journal of experimental medicine 191 (4), 669-682, 2000 | 332 | 2000 |
Ligand-regulated chimeric receptor approach reveals distinctive subcellular localization and signaling properties of the Toll-like receptors T Nishiya, AL DeFranco Journal of Biological Chemistry 279 (18), 19008-19017, 2004 | 328 | 2004 |
Tyrosine phosphorylation of components of the B-cell antigen receptors following receptor crosslinking. MR Gold, L Matsuuchi, RB Kelly, AL DeFranco Proceedings of the National Academy of Sciences 88 (8), 3436-3440, 1991 | 312 | 1991 |
TLR3 and TLR7 are targeted to the same intracellular compartments by distinct regulatory elements T Nishiya, E Kajita, S Miwa, AL DeFranco Journal of Biological Chemistry 280 (44), 37107-37117, 2005 | 283 | 2005 |
Expression of A20 by dendritic cells preserves immune homeostasis and prevents colitis and spondyloarthritis GE Hammer, EE Turer, KE Taylor, CJ Fang, R Advincula, S Oshima, ... Nature immunology 12 (12), 1184-1193, 2011 | 279 | 2011 |
CD19 regulates Src family protein tyrosine kinase activation in B lymphocytes through processive amplification M Fujimoto, Y Fujimoto, JC Poe, PJ Jansen, CA Lowell, AL DeFranco, ... Immunity 13 (1), 47-57, 2000 | 273 | 2000 |
Selective utilization of Toll-like receptor and MyD88 signaling in B cells for enhancement of the antiviral germinal center response B Hou, P Saudan, G Ott, ML Wheeler, M Ji, L Kuzmich, LM Lee, ... Immunity 34 (3), 375-384, 2011 | 272 | 2011 |
Quantitative proteomic analysis of B cell lipid rafts reveals that ezrin regulates antigen receptor–mediated lipid raft dynamics N Gupta, B Wollscheid, JD Watts, B Scheer, R Aebersold, AL DeFranco Nature immunology 7 (6), 625-633, 2006 | 244 | 2006 |
Antigen presentation by resting B cells. Radiosensitivity of the antigen-presentation function and two distinct pathways of T cell activation. JD Ashwell, AL DeFranco, WE Paul, RH Schwartz The Journal of experimental medicine 159 (3), 881-905, 1984 | 241 | 1984 |
Visualizing lipid raft dynamics and early signaling events during antigen receptor-mediated B-lymphocyte activation N Gupta, AL DeFranco Molecular biology of the cell 14 (2), 432-444, 2003 | 224 | 2003 |