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Suresh Kumar Agarwal, MS, PhD, RPH
Suresh Kumar Agarwal, MS, PhD, RPH
Director, Clincal Pharmacology
Correu electrònic verificat a bmrn.com
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Safety and preliminary efficacy of venetoclax with decitabine or azacitidine in elderly patients with previously untreated acute myeloid leukaemia: a non-randomised, open-label …
CD DiNardo, KW Pratz, A Letai, BA Jonas, AH Wei, M Thirman, ...
The lancet oncology 19 (2), 216-228, 2018
7612018
Venetoclax combined with low-dose cytarabine for previously untreated patients with acute myeloid leukemia: results from a phase Ib/II study
AH Wei, SA Strickland Jr, JZ Hou, W Fiedler, TL Lin, RB Walter, A Enjeti, ...
Journal of Clinical Oncology 37 (15), 1277-1284, 2019
6982019
Efficacy of venetoclax as targeted therapy for relapsed/refractory t (11; 14) multiple myeloma
S Kumar, JL Kaufman, C Gasparetto, J Mikhael, R Vij, B Pegourie, ...
Blood, The Journal of the American Society of Hematology 130 (22), 2401-2409, 2017
5642017
Venetoclax plus rituximab in relapsed or refractory chronic lymphocytic leukaemia: a phase 1b study
JF Seymour, S Ma, DM Brander, MY Choi, J Barrientos, MS Davids, ...
The Lancet Oncology 18 (2), 230-240, 2017
3982017
Management of venetoclax-posaconazole interaction in acute myeloid leukemia patients: evaluation of dose adjustments
SK Agarwal, CD DiNardo, J Potluri, M Dunbar, HM Kantarjian, ...
Clinical Therapeutics 39 (2), 359-367, 2017
2122017
Venetoclax for patients with chronic lymphocytic leukemia who progressed during or after idelalisib therapy
S Coutre, M Choi, RR Furman, H Eradat, L Heffner, JA Jones, B Chyla, ...
Blood, The Journal of the American Society of Hematology 131 (15), 1704-1711, 2018
1752018
Pharmacokinetics of venetoclax, a novel BCL‐2 inhibitor, in patients with relapsed or refractory chronic lymphocytic leukemia or non‐Hodgkin lymphoma
AH Salem, SK Agarwal, M Dunbar, SLH Enschede, RA Humerickhouse, ...
The Journal of Clinical Pharmacology 57 (4), 484-492, 2017
1212017
Updated results from phase I dose-escalation study of AMG 330, a bispecific T-cell engager molecule, in patients with relapsed/refractory acute myeloid leukemia (R/R AML).
F Ravandi, RB Walter, M Subklewe, V Buecklein, M Jongen-Lavrencic, ...
Journal of Clinical Oncology 38 (15_suppl), 7508-7508, 2020
1042020
Effect of ketoconazole, a strong CYP3A inhibitor, on the pharmacokinetics of venetoclax, a BCL‐2 inhibitor, in patients with non‐Hodgkin lymphoma
SK Agarwal, AH Salem, AV Danilov, B Hu, S Puvvada, M Gutierrez, ...
British journal of clinical pharmacology 83 (4), 846-854, 2017
992017
Statins enhance efficacy of venetoclax in blood cancers
JS Lee, A Roberts, D Juarez, TTT Vo, S Bhatt, L Herzog, S Mallya, ...
Science translational medicine 10 (445), eaaq1240, 2018
952018
Evaluation of rifampin's transporter inhibitory and CYP3A inductive effects on the pharmacokinetics of venetoclax, a BCL‐2 inhibitor: results of a single‐and multiple‐dose study
SK Agarwal, B Hu, D Chien, SL Wong, AH Salem
The Journal of Clinical Pharmacology 56 (11), 1335-1343, 2016
952016
Clinical predictors of venetoclax pharmacokinetics in chronic lymphocytic leukemia and non-Hodgkin’s lymphoma patients: a pooled population pharmacokinetic analysis
AK Jones, KJ Freise, SK Agarwal, RA Humerickhouse, SL Wong, ...
The AAPS journal 18, 1192-1202, 2016
932016
Effect of low‐and high‐fat meals on the pharmacokinetics of venetoclax, a selective first‐in‐class BCL‐2 inhibitor
AH Salem, SK Agarwal, M Dunbar, S Nuthalapati, D Chien, KJ Freise, ...
The Journal of Clinical Pharmacology 56 (11), 1355-1361, 2016
892016
A phase 1 first-in-human study of AMG 330, an anti-CD33 bispecific T-cell engager (BiTE®) antibody construct, in relapsed/refractory acute myeloid leukemia (R/R AML)
F Ravandi, AS Stein, HM Kantarjian, RB Walter, P Paschka, ...
Blood 132, 25, 2018
872018
A pilot study assessing the bioavailability and pharmacokinetics of diazepam after intranasal and intravenous administration in healthy volunteers
SK Agarwal, RL Kriel, RC Brundage, VD Ivaturi, JC Cloyd
Epilepsy research 105 (3), 362-367, 2013
822013
Preliminary results from a phase 1 first-in-human study of AMG 673, a novel half-life extended (HLE) anti-CD33/CD3 BiTE®(bispecific T-cell engager) in patients with relapsed …
M Subklewe, A Stein, RB Walter, R Bhatia, AH Wei, D Ritchie, V Bücklein, ...
Blood 134, 833, 2019
812019
Metabolism and disposition of a novel B-cell lymphoma-2 inhibitor venetoclax in humans and characterization of its unusual metabolites
H Liu, MJ Michmerhuizen, Y Lao, K Wan, AH Salem, J Sawicki, M Serby, ...
Drug Metabolism and Disposition 45 (3), 294-305, 2017
772017
Venetoclax, bendamustine, and rituximab in patients with relapsed or refractory NHL: a phase Ib dose-finding study
S de Vos, LJ Swinnen, D Wang, E Reid, N Fowler, J Cordero, M Dunbar, ...
Annals of Oncology 29 (9), 1932-1938, 2018
752018
A phase 1b study of venetoclax (ABT-199/GDC-0199) in combination with decitabine or azacitidine in treatment-naive patients with acute myelogenous leukemia who are≥ to 65 …
C DiNardo, D Pollyea, K Pratz, MJ Thirman, A Letai, M Frattini, B Jonas, ...
Blood 126 (23), 327, 2015
702015
Safety and efficacy of venetoclax plus low-dose cytarabine in treatment-naive patients aged≥ 65 years with acute myeloid leukemia
A Wei, SA Strickland, GJ Roboz, JZ Hou, W Fiedler, TL Lin, G Martinelli, ...
Blood 128 (22), 102, 2016
652016
En aquests moments el sistema no pot dur a terme l'operació. Torneu-ho a provar més tard.
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