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Joanna Lee Bradford
Joanna Lee Bradford
Principal Scientist, Genentech
Correu electrònic verificat a gene.com
Títol
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Matrix mechanical plasticity regulates cancer cell migration through confining microenvironments
KM Wisdom, K Adebowale, J Chang, JY Lee, S Nam, R Desai, ...
Nature communications 9 (1), 4144, 2018
3872018
Massively parallel X-ray holography
S Marchesini, S Boutet, AE Sakdinawat, MJ Bogan, S Bajt, A Barty, ...
Nature photonics 2 (9), 560-563, 2008
2172008
Viscoplasticity enables mechanical remodeling of matrix by cells
S Nam, J Lee, DG Brownfield, O Chaudhuri
Biophysical journal 111 (10), 2296-2308, 2016
1982016
YAP-independent mechanotransduction drives breast cancer progression
JY Lee, JK Chang, AA Dominguez, H Lee, S Nam, J Chang, S Varma, ...
Nature communications 10 (1), 1848, 2019
1912019
Cell cycle progression in confining microenvironments is regulated by a growth-responsive TRPV4-PI3K/Akt-p27Kip1 signaling axis
S Nam, VK Gupta, H Lee, JY Lee, KM Wisdom, S Varma, EM Flaum, ...
Science advances 5 (8), eaaw6171, 2019
1682019
Spiroplasma swim by a processive change in body helicity
JW Shaevitz, JY Lee, DA Fletcher
Cell 122 (6), 941-945, 2005
1642005
FOP is a centriolar satellite protein involved in ciliogenesis
JY Lee, T Stearns
PloS one 8 (3), e58589, 2013
642013
Femtosecond diffractive imaging of biological cells
MM Seibert, S Boutet, M Svenda, T Ekeberg, FRNC Maia, MJ Bogan, ...
Journal of Physics B: Atomic, Molecular and Optical Physics 43 (19), 194015, 2010
622010
Regulation of breast cancer progression by extracellular matrix mechanics: insights from 3D culture models
JY Lee, O Chaudhuri
ACS Biomaterials Science & Engineering 4 (2), 302-313, 2018
392018
Identification of cell context-dependent YAP-associated proteins reveals β1 and β4 integrin mediate YAP translocation independently of cell spreading
JY Lee, AA Dominguez, S Nam, RS Stowers, LS Qi, O Chaudhuri
Scientific reports 9 (1), 17188, 2019
242019
Modeling the tumor immune microenvironment for drug discovery using 3D culture
JY Lee, O Chaudhuri
APL bioengineering 5 (1), 2021
192021
Structure-based design of potent, selective, and orally bioavailable VPS34 kinase inhibitors
DX Hu, S Patel, H Chen, S Wang, ST Staben, YN Dimitrova, ...
Journal of Medicinal Chemistry 65 (17), 11500-11512, 2021
172021
Development of a robust flow cytometry-based pharmacodynamic assay to detect phospho-protein signals for phosphatidylinositol 3-kinase inhibitors in multiple myeloma
C Li, C Takahashi, L Zhang, M Huseni, B Stankovich, H Mashhedi, J Lee, ...
Journal of Translational Medicine 11, 1-10, 2013
132013
Centrosome-kinase fusions promote oncogenic signaling and disrupt centrosome function in myeloproliferative neoplasms
JY Lee, WJ Hong, R Majeti, T Stearns
PLoS One 9 (3), e92641, 2014
102014
En aquests moments el sistema no pot dur a terme l'operació. Torneu-ho a provar més tard.
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