Machine and deep learning approaches for cancer drug repurposing NT Issa, V Stathias, S Schürer, S Dakshanamurthy Seminars in cancer biology 68, 132-142, 2021 | 218 | 2021 |
Predicting new indications for approved drugs using a proteochemometric method S Dakshanamurthy, NT Issa, S Assefnia, A Seshasayee, OJ Peters, ... Journal of medicinal chemistry 55 (15), 6832-6848, 2012 | 193 | 2012 |
The role of the skin and gut microbiome in psoriatic disease D Yan, N Issa, L Afifi, C Jeon, HW Chang, W Liao Current dermatology reports 6, 94-103, 2017 | 144 | 2017 |
Drug metabolism in preclinical drug development: a survey of the discovery process, toxicology, and computational tools N T Issa, H Wathieu, A Ojo, S W Byers, S Dakshanamurthy Current drug metabolism 18 (6), 556-565, 2017 | 129 | 2017 |
Big data: the next frontier for innovation in therapeutics and healthcare NT Issa, SW Byers, S Dakshanamurthy Expert review of clinical pharmacology 7 (3), 293-298, 2014 | 120 | 2014 |
Treatment of androgenetic alopecia: current guidance and unmet needs M Kaiser, R Abdin, SI Gaumond, NT Issa, JJ Jimenez Clinical, cosmetic and investigational dermatology, 1387-1406, 2023 | 41 | 2023 |
Drug repurposing a reality: from computers to the clinic NT Issa, J Kruger, SW Byers, S Dakshanamurthy Expert review of clinical pharmacology 6 (2), 95-97, 2013 | 31 | 2013 |
DrugGenEx-Net: a novel computational platform for systems pharmacology and gene expression-based drug repurposing NT Issa, J Kruger, H Wathieu, R Raja, SW Byers, S Dakshanamurthy BMC bioinformatics 17, 1-18, 2016 | 29 | 2016 |
Tumor suppressor RARRES1-A novel regulator of fatty acid metabolism in epithelial cells S Maimouni, N Issa, S Cheng, C Ouaari, A Cheema, D Kumar, S Byers PloS one 13 (12), e0208756, 2018 | 26 | 2018 |
Drug repurposing: translational pharmacology, chemistry, computers and the clinic N T Issa, S W Byers, S Dakshanamurthy Current Topics in Medicinal Chemistry 13 (18), 2328-2336, 2013 | 25 | 2013 |
Amend SR Seminars in Cancer Biology KJ Pienta, EU Hammarlund, RH Austin, R Axelrod, JS Brown Academic Press, 2020 | 21 | 2020 |
RepurposeVS: a drug repurposing-focused computational method for accurate drug-target signature predictions N T Issa, O J Peters, S W Byers, S Dakshanamurthy Combinatorial chemistry & high throughput screening 18 (8), 784-794, 2015 | 20 | 2015 |
Research techniques made simple: Molecular docking in dermatology-A foray into in silico drug discovery NT Issa, EV Badiavas, S Schürer Journal of Investigative Dermatology 139 (12), 2400-2408. e1, 2019 | 18 | 2019 |
Differential prioritization of therapies to subtypes of triple negative breast cancer using a systems medicine method H Wathieu, NT Issa, AI Fernandez, M Mohandoss, DM Tiek, JL Franke, ... Oncotarget 8 (54), 92926, 2017 | 13 | 2017 |
Alopecia after cosmetic injection procedures: a review NT Issa, M Kaiser, A Martinez-Velasco, A Tosti Dermatologic Surgery 48 (8), 855-861, 2022 | 11 | 2022 |
Harnessing polypharmacology with computer-aided drug design and systems biology H Wathieu, N T Issa, S W Byers, S Dakshanamurthy Current pharmaceutical design 22 (21), 3097-3108, 2016 | 11 | 2016 |
A novel chemo-phenotypic method identifies mixtures of salpn, vitamin D3, and pesticides involved in the development of colorectal and pancreatic cancer NT Issa, H Wathieu, E Glasgow, I Peran, E Parasido, T Li, ... Ecotoxicology and environmental safety 233, 113330, 2022 | 8 | 2022 |
Coffee and skin—Considerations beyond the caffeine perspective ER Bray, RS Kirsner, NT Issa Journal of the American Academy of Dermatology 82 (2), e63, 2020 | 6 | 2020 |
Beard alopecia: an updated and comprehensive review of etiologies, presentation and treatment M Kaiser, R Abdin, M Yaghi, SI Gaumond, JJ Jimenez, NT Issa Journal of Clinical Medicine 12 (14), 4793, 2023 | 5 | 2023 |
First use of tapinarof monotherapy for seborrhoeic dermatitis: A case report TI Naiem, M Kaiser Acta Dermato-Venereologica 103, 12343, 2023 | 5 | 2023 |