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Leandro Cerchietti
Leandro Cerchietti
Weill Cornell Medicine
Correu electrònic verificat a med.cornell.edu - Pàgina d'inici
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EZH2 is required for germinal center formation and somatic EZH2 mutations promote lymphoid transformation
W Béguelin, R Popovic, M Teater, Y Jiang, KL Bunting, M Rosen, H Shen, ...
Cancer cell 23 (5), 677-692, 2013
9722013
Hsp90 inhibitor PU-H71, a multimodal inhibitor of malignancy, induces complete responses in triple-negative breast cancer models
E Caldas-Lopes, L Cerchietti, JH Ahn, CC Clement, AI Robles, A Rodina, ...
Proceedings of the National Academy of Sciences 106 (20), 8368-8373, 2009
3782009
Specific peptide interference reveals BCL6 transcriptional and oncogenic mechanisms in B-cell lymphoma cells
JM Polo, T Dell'Oso, SM Ranuncolo, L Cerchietti, D Beck, GF Da Silva, ...
Nature medicine 10 (12), 1329-1335, 2004
3582004
A small-molecule inhibitor of BCL6 kills DLBCL cells in vitro and in vivo
LC Cerchietti, AF Ghetu, X Zhu, GF Da Silva, S Zhong, M Matthews, ...
Cancer cell 17 (4), 400-411, 2010
3572010
Affinity-based proteomics reveal cancer-specific networks coordinated by Hsp90
K Moulick, JH Ahn, H Zong, A Rodina, L Cerchietti, EM Gomes DaGama, ...
Nature chemical biology 7 (11), 818-826, 2011
3092011
The BCL6 transcriptional program features repression of multiple oncogenes in primary B cells and is deregulated in DLBCL
W Ci, JM Polo, L Cerchietti, R Shaknovich, L Wang, SN Yang, K Ye, ...
Blood, The Journal of the American Society of Hematology 113 (22), 5536-5548, 2009
2832009
MALT1 small molecule inhibitors specifically suppress ABC-DLBCL in vitro and in vivo
L Fontan, C Yang, V Kabaleeswaran, L Volpon, MJ Osborne, E Beltran, ...
Cancer cell 22 (6), 812-824, 2012
2822012
The epichaperome is an integrated chaperome network that facilitates tumour survival
A Rodina, T Wang, P Yan, EDG Gomes, MPS Dunphy, N Pillarsetty, ...
Nature 538 (7625), 397-401, 2016
2772016
Midazolam as adjunct therapy to morphine in the alleviation of severe dyspnea perception in patients with advanced cancer
AH Navigante, LCA Cerchietti, MA Castro, MA Lutteral, ME Cabalar
Journal of pain and symptom management 31 (1), 38-47, 2006
2742006
Kaiso-deficient mice show resistance to intestinal cancer
A Prokhortchouk, O Sansom, J Selfridge, IM Caballero, S Salozhin, ...
Molecular and cellular biology 26 (1), 199-208, 2006
2332006
Mechanism-based epigenetic chemosensitization therapy of diffuse large B-cell lymphoma
T Clozel, SN Yang, RL Elstrom, W Tam, P Martin, M Kormaksson, ...
Cancer discovery 3 (9), 1002-1019, 2013
2242013
BCL6 enables Ph+ acute lymphoblastic leukaemia cells to survive BCR–ABL1 kinase inhibition
C Duy, C Hurtz, S Shojaee, L Cerchietti, H Geng, S Swaminathan, ...
Nature 473 (7347), 384-388, 2011
2202011
A purine scaffold Hsp90 inhibitor destabilizes BCL-6 and has specific antitumor activity in BCL-6–dependent B cell lymphomas
LC Cerchietti, EC Lopes, SN Yang, K Hatzi, KL Bunting, LA Tsikitas, ...
Nature medicine 15 (12), 1369-1376, 2009
2092009
The sonic hedgehog factor GLI1 imparts drug resistance through inducible glucuronidation
HA Zahreddine, B Culjkovic-Kraljacic, S Assouline, P Gendron, ...
Nature 511 (7507), 90-93, 2014
2072014
Effect of topical morphine for mucositis‐associated pain following concomitant chemoradiotherapy for head and neck carcinoma
LCA Cerchietti, AH Navigante, MR Bonomi, MA Zaderajko, PR Menéndez, ...
Cancer: Interdisciplinary International Journal of the American Cancer …, 2002
2062002
A peptomimetic inhibitor of BCL6 with potent antilymphoma effects in vitro and in vivo
LC Cerchietti, SN Yang, R Shaknovich, K Hatzi, JM Polo, A Chadburn, ...
Blood, The Journal of the American Society of Hematology 113 (15), 3397-3405, 2009
2022009
BCL6-mediated repression of p53 is critical for leukemia stem cell survival in chronic myeloid leukemia
C Hurtz, K Hatzi, L Cerchietti, M Braig, E Park, Y Kim, S Herzog, ...
Journal of Experimental Medicine 208 (11), 2163-2174, 2011
2002011
Limits in the detection of m6A changes using MeRIP/m6A-seq
ABR McIntyre, NS Gokhale, L Cerchietti, SR Jaffrey, SM Horner, ...
Scientific reports 10 (1), 6590, 2020
1982020
A hybrid mechanism of action for BCL6 in B cells defined by formation of functionally distinct complexes at enhancers and promoters
K Hatzi, Y Jiang, C Huang, F Garrett-Bakelman, MD Gearhart, ...
Cell reports 4 (3), 578-588, 2013
1982013
Clinical and biological subtypes of B-cell lymphoma revealed by microenvironmental signatures
N Kotlov, A Bagaev, MV Revuelta, JM Phillip, MT Cacciapuoti, ...
Cancer discovery 11 (6), 1468-1489, 2021
1822021
En aquests moments el sistema no pot dur a terme l'operació. Torneu-ho a provar més tard.
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