PTK787/ZK 222584, a novel and potent inhibitor of vascular endothelial growth factor receptor tyrosine kinases, impairs vascular endothelial growth factor-induced responses and … JM Wood, G Bold, E Buchdunger, R Cozens, S Ferrari, J Frei, F Hofmann, ... Cancer research 60 (8), 2178-2189, 2000 | 1065 | 2000 |
Combination of Ru (II) complexes and light: new frontiers in cancer therapy C Mari, V Pierroz, S Ferrari, G Gasser Chemical science 6 (5), 2660-2686, 2015 | 616 | 2015 |
Rapamycin inhibition of the G1 to S transition is mediated by effects on cyclin D1 mRNA and protein stability S Hashemolhosseini, Y Nagamine, SJ Morley, S Desrivieres, L Mercep, ... Journal of Biological Chemistry 273 (23), 14424-14429, 1998 | 437 | 1998 |
New anilinophthalazines as potent and orally well absorbed inhibitors of the VEGF receptor tyrosine kinases useful as antagonists of tumor-driven angiogenesis G Bold, KH Altmann, J Frei, M Lang, PW Manley, P Traxler, B Wietfeld, ... Journal of medicinal chemistry 43 (12), 2310-2323, 2000 | 332 | 2000 |
Molecular and Cellular Characterization of the Biological Effects of Ruthenium (II) Complexes Incorporating 2-Pyridyl-2-pyrimidine-4-carboxylic Acid V Pierroz, T Joshi, A Leonidova, C Mari, J Schur, I Ott, L Spiccia, S Ferrari, ... Journal of the American Chemical Society, 2012 | 317 | 2012 |
Mismatch repair-dependent G2 checkpoint induced by low doses of SN1 type methylating agents requires the ATR kinase L Stojic, N Mojas, P Cejka, M Di Pietro, S Ferrari, G Marra, J Jiricny Genes & development 18 (11), 1331-1344, 2004 | 303 | 2004 |
Cloning of the mitogen-activated S6 kinase from rat liver reveals an enzyme of the second messenger subfamily. SC Kozma, S Ferrari, P Bassand, M Siegmann, N Totty, G Thomas Proceedings of the National Academy of Sciences 87 (19), 7365-7369, 1990 | 223 | 1990 |
Mitogen-activated 70K S6 kinase. Identification of in vitro 40 S ribosomal S6 phosphorylation sites. S Ferrari, HR Bandi, J Hofsteenge, BM Bussian, G Thomas Journal of Biological Chemistry 266 (33), 22770-22775, 1991 | 205 | 1991 |
DNA Intercalating RuII Polypyridyl Complexes as Effective Photosensitizers in Photodynamic Therapy C Mari, V Pierroz, R Rubbiani, M Patra, J Hess, B Spingler, L Oehninger, ... Chemistry–A European Journal 20 (44), 14421-14436, 2014 | 204 | 2014 |
Activation of p70s6k is associated with phosphorylation of four clustered sites displaying Ser/Thr-Pro motifs. S Ferrari, W Bannwarth, SJ Morley, NF Totty, G Thomas Proceedings of the National Academy of Sciences 89 (15), 7282-7286, 1992 | 197 | 1992 |
Insulin-stimulated protein kinase B phosphorylation on Ser-473 is independent of its activity and occurs through a staurosporine-insensitive kinase MM Hill, M Andjelkovic, DP Brazil, S Ferrari, D Fabbro, BA Hemmings Journal of Biological Chemistry 276 (28), 25643-25646, 2001 | 191 | 2001 |
The calcium-binding protein S100A2 interacts with p53 and modulates its transcriptional activity A Mueller, BW Schäfer, S Ferrari, M Weibel, M Makek, M Höchli, ... Journal of Biological Chemistry 280 (32), 29186-29193, 2005 | 190 | 2005 |
Inhibitors of protein kinases: CGP 41251, a protein kinase inhibitor with potential as an anticancer agent D Fabbro, E Buchdunger, J Wood, J Mestan, F Hofmann, S Ferrari, H Mett, ... Pharmacology & therapeutics 82 (2-3), 293-301, 1999 | 188 | 1999 |
Towards cancer cell-specific phototoxic organometallic rhenium (I) complexes A Leonidova, V Pierroz, R Rubbiani, J Heier, S Ferrari, G Gasser Dalton Transactions 43 (11), 4287-4294, 2014 | 183 | 2014 |
DMSO-Mediated Ligand Dissociation: Renaissance for Biological Activity of N-Heterocyclic-[Ru(η6-arene)Cl2] Drug Candidates. M Patra, T Joshi, V Pierroz, K Ingram, M Kaiser, S Ferrari, B Spingler, ... Chemistry-A European Journal 19 (44), 2013 | 172 | 2013 |
Vascular endothelial growth factor (VEGF) receptor-2 antagonists inhibit VEGF-and basic fibroblast growth factor-induced angiogenesis in vivo and in vitro JC Tille, J Wood, SJ Mandriota, C Schnell, S Ferrari, J Mestan, Z Zhu, ... The Journal of pharmacology and experimental therapeutics 299 (3), 1073-1085, 2001 | 172 | 2001 |
DNA end resection by CtIP and exonuclease 1 prevents genomic instability W Eid, M Steger, M El‐Shemerly, LP Ferretti, J Peña‐Diaz, C König, ... EMBO reports 11 (12), 962-968, 2010 | 170 | 2010 |
S6 Phosphorylation and the p70s6k/p85s6k S Ferrari, G Thomas Critical reviews in biochemistry and molecular biology 29 (6), 385-413, 1994 | 169 | 1994 |
PET/MRI in head and neck cancer: initial experience I Platzek, B Beuthien-Baumann, M Schneider, V Gudziol, J Langner, ... European journal of nuclear medicine and molecular imaging 40, 6-11, 2013 | 166* | 2013 |
The immunosuppressant rapamycin induces inactivation of p70s6k through dephosphorylation of a novel set of sites S Ferrari, RB Pearson, M Siegmann, SC Kozma, G Thomas Journal of Biological Chemistry 268 (22), 16091-16094, 1993 | 147 | 1993 |