| C-terminal calcium binding of α-synuclein modulates synaptic vesicle interaction J Lautenschläger, AD Stephens, G Fusco, F Ströhl, N Curry, ... Nature communications 9 (1), 712, 2018 | 317 | 2018 |
| Extent of N-terminus exposure of monomeric alpha-synuclein determines its aggregation propensity AD Stephens, M Zacharopoulou, R Moons, G Fusco, N Seetaloo, A Chiki, ... Nature communications 11 (1), 2820, 2020 | 138 | 2020 |
| Engineering the surface properties of a human monoclonal antibody prevents self-association and rapid clearance in vivo CL Dobson, PWA Devine, JJ Phillips, DR Higazi, C Lloyd, B Popovic, ... Scientific reports 6 (1), 38644, 2016 | 131 | 2016 |
| Structural and dynamic insights into the energetics of activation loop rearrangement in FGFR1 kinase T Klein, N Vajpai, JJ Phillips, G Davies, GA Holdgate, C Phillips, ... Nature communications 6 (1), 7877, 2015 | 78 | 2015 |
| Conformational dynamics of the molecular chaperone Hsp90 in complexes with a co-chaperone and anticancer drugs JJ Phillips, Z Yao, W Zhang, S McLaughlin, ED Laue, CV Robinson, ... Journal of molecular biology 372 (5), 1189-1203, 2007 | 62 | 2007 |
| The rate of asparagine deamidation in a monoclonal antibody correlates with hydrogen exchange rate at adjacent downstream residues JJ Phillips, A Buchanan, J Andrews, M Chodorge, S Sridharan, L Mitchell, ... Analytical Chemistry 89 (4), 2361-2368, 2017 | 50 | 2017 |
| Different structural conformers of monomeric α-synuclein identified after lyophilizing and freezing AD Stephens, N Nespovitaya, M Zacharopoulou, CF Kaminski, JJ Phillips, ... Analytical Chemistry 90 (11), 6975-6983, 2018 | 43 | 2018 |
| Fibrous nanostructures from the self-assembly of designed repeat protein modules. JJ Phillips, C Millership, ER Main Angewandte Chemie (International ed. in English) 51 (52), 13132-13135, 2012 | 40 | 2012 |
| Global and local conformation of human IgG antibody variants rationalizes loss of thermodynamic stability MJ Edgeworth, JJ Phillips, DC Lowe, AD Kippen, DR Higazi, JH Scrivens Angewandte Chemie International Edition 54 (50), 15156-15159, 2015 | 38 | 2015 |
| Engineering and exploiting synthetic allostery of NanoLuc luciferase Z Guo, RD Parakra, Y Xiong, WA Johnston, P Walden, S Edwardraja, ... Nature Communications 13 (1), 789, 2022 | 31 | 2022 |
| Modulation of the multistate folding of designed TPR proteins through intrinsic and extrinsic factors JJ Phillips, Y Javadi, C Millership, ERG Main Protein Science 21 (3), 327-338, 2012 | 30 | 2012 |
| Repeat protein engineering: creating functional nanostructures/biomaterials from modular building blocks ERG Main, JJ Phillips, C Millership Biochemical Society Transactions 41 (5), 1152-1158, 2013 | 29 | 2013 |
| Understanding the relationship between biotherapeutic protein stability and solid–liquid interfacial shear in constant region mutants of IgG1 and IgG4 R Tavakoli-Keshe, JJ Phillips, R Turner, DG Bracewell Journal of pharmaceutical sciences 103 (2), 437-444, 2014 | 28 | 2014 |
| Ising model reprogramming of a repeat protein's equilibrium unfolding pathway C Millership, JJ Phillips, ERG Main Journal of Molecular Biology 428 (9), 1804-1817, 2016 | 22 | 2016 |
| HDfleX: Software for Flexible High Structural Resolution of Hydrogen/Deuterium-Exchange Mass Spectrometry Data N Seetaloo, M Kish, JJ Phillips Analytical Chemistry 94 (11), 4557-4564, 2022 | 21 | 2022 |
| Online fully automated system for Hydrogen/Deuterium-exchange mass spectrometry with millisecond time resolution M Kish, V Smith, N Lethbridge, L Cole, NJ Bond, JJ Phillips Analytical Chemistry 95 (11), 5000-5008, 2023 | 16 | 2023 |
| Allosteric regulation of glycogen phosphorylase solution phase structural dynamics at high spatial resolution M Kish, V Smith, S Subramanian, F Vollmer, N Lethbridge, L Cole, ... BioRxiv, 654665, 2019 | 16 | 2019 |
| Millisecond hydrogen/deuterium-exchange mass spectrometry approach to correlate local structure and aggregation in α-synuclein N Seetaloo, M Zacharopoulou, AD Stephens, GS Kaminski Schierle, ... Analytical Chemistry 94 (48), 16711-16719, 2022 | 13 | 2022 |
| Characterization of monoclonal antibody aggregates and emerging technologies RL Remmele Jr, JS Bee, JJ Phillips, WD Mo, DR Higazi, J Zhang, V Lindo, ... State-of-the-Art and Emerging Technologies for Therapeutic Monoclonal …, 2015 | 13 | 2015 |
| Mechanistic insights into the rational design of masked antibodies CT Orozco, M Bersellini, LM Irving, WW Howard, D Hargreaves, ... MAbs 14 (1), 2095701, 2022 | 9 | 2022 |
Carol V RobinsonProfessor of Chemistry University of OxfordCorreu electrònic verificat a chem.ox.ac.uk