Chemoprotection by organosulfur inducers of phase 2 enzymes: dithiolethiones and dithiins. RBD Kensler TW, Curphey TJ, Maxiutenko Y Drug Metabol Drug Interact. 17 (1-4), 3-22, 2000 | 158 | 2000 |
Transient intervention with oltipraz protects against aflatoxin-induced hepatic tumorigenesis MG Bolton, A Muñoz, LP Jacobson, JD Groopman, YY Maxuitenko, ... Cancer research 53 (15), 3499-3504, 1993 | 122 | 1993 |
A novel sulindac derivative that does not inhibit cyclooxygenases but potently inhibits colon tumor cell growth and induces apoptosis with antitumor activity GA Piazza, AB Keeton, HN Tinsley, BD Gary, JD Whitt, B Mathew, ... Cancer Prevention Research 2 (6), 572-580, 2009 | 112 | 2009 |
Sorafenib is efficacious and tolerated in combination with cytotoxic or cytostatic agents in preclinical models of human non-small cell lung carcinoma CA Carter, C Chen, C Brink, P Vincent, YY Maxuitenko, KS Gilbert, ... Cancer chemotherapy and pharmacology 59, 183-195, 2007 | 110 | 2007 |
Colon tumor cell growth–inhibitory activity of sulindac sulfide and other nonsteroidal anti-inflammatory drugs is associated with phosphodiesterase 5 inhibition HN Tinsley, BD Gary, J Thaiparambil, N Li, W Lu, Y Li, YY Maxuitenko, ... Cancer Prevention Research 3 (10), 1303-1313, 2010 | 95 | 2010 |
Identification of dithiolethiones with better chemopreventive properties than oltipraz. YY Maxuitenko, AH Libby, HH Joyner, TJ Curphey, DL MacMillan, ... Carcinogenesis 19 (9), 1609-1615, 1998 | 88 | 1998 |
Biochemical mechanisms and biological implications of the toxicity of aflatoxins as related to aflatoxin carcinogenesis. BD Roebuck, YY Maxuitenko | 87 | 1993 |
Novel DNA methyltransferase-1 (DNMT1) depleting anticancer nucleosides, 4′-thio-2′-deoxycytidine and 5-aza-4′-thio-2′-deoxycytidine JV Thottassery, V Sambandam, PW Allan, JA Maddry, YY Maxuitenko, ... Cancer chemotherapy and pharmacology 74, 291-302, 2014 | 69 | 2014 |
Vascular endothelial growth factor reduces tamoxifen efficacy and promotes metastatic colonization and desmoplasia in breast tumors Z Qu, S Van Ginkel, AM Roy, L Westbrook, M Nasrin, Y Maxuitenko, ... Cancer research 68 (15), 6232-6240, 2008 | 61 | 2008 |
PDE5 and PDE10 inhibition activates cGMP/PKG signaling to block Wnt/β-catenin transcription, cancer cell growth, and tumor immunity GA Piazza, A Ward, X Chen, Y Maxuitenko, A Coley, NS Aboelella, ... Drug discovery today 25 (8), 1521-1527, 2020 | 58 | 2020 |
A novel polyamine analog (SL-11093) inhibits growth of human prostate tumor xenografts in nude mice B Frydman, CW Porter, Y Maxuitenko, A Sarkar, S Bhattacharya, ... Cancer chemotherapy and pharmacology 51, 488-492, 2003 | 50 | 2003 |
Cyclopropane-containing polyamine analogues are efficient growth inhibitors of a human prostate tumor xenograft in nude mice B Frydman, AV Blokhin, S Brummel, G Wilding, Y Maxuitenko, A Sarkar, ... Journal of medicinal chemistry 46 (21), 4586-4600, 2003 | 47 | 2003 |
Evaluation of the post-initiation effects of oltipraz on aflatoxin B1-induced preneoplastic foci in a rat model of hepatic tumorigenesis YY Maxuitenko, DL MacMillan, TW Kensler, BD Roebuck Carcinogenesis 14 (11), 2423-2425, 1993 | 42 | 1993 |
Protection against Aflatoxin B1-Induced Hepatic Toxicity as a Short-Term Screen of Cancer Chemopreventive Dithiolethiones YY Maxuitenko, TJ Curphey, TW Kensler, BD Roebuck Toxicological Sciences 32 (2), 250-259, 1996 | 34 | 1996 |
Exploiting RAS nucleotide cycling as a strategy for drugging RAS-driven cancers TE Mattox, X Chen, YY Maxuitenko, AB Keeton, GA Piazza International Journal of Molecular Sciences 21 (1), 141, 2019 | 25 | 2019 |
Pharmacological inhibition of ABCC3 slows tumour progression in animal models of pancreatic cancer A Adamska, A Domenichini, E Capone, V Damiani, BG Akkaya, KJ Linton, ... Journal of Experimental & Clinical Cancer Research 38, 1-14, 2019 | 25 | 2019 |
Enhancing anticancer activity of checkpoint immunotherapy by targeting RAS AB Ward, AB Keeton, X Chen, TE Mattox, AB Coley, YY Maxuitenko, ... MedComm 1 (2), 121-128, 2020 | 22 | 2020 |
From celecoxib to a novel class of phosphodiesterase 5 inhibitors: Trisubstituted pyrazolines as novel phosphodiesterase 5 inhibitors with extremely high potency and … M Abdel-Halim, S Sigler, NAS Racheed, A Hefnawy, RK Fathalla, ... Journal of Medicinal Chemistry 64 (8), 4462-4477, 2021 | 21 | 2021 |
Inhibition of the lysophosphatidylinositol transporter ABCC1 reduces prostate cancer cell growth and sensitizes to chemotherapy A Emmanouilidi, I Casari, B Gokcen Akkaya, T Maffucci, L Furic, F Guffanti, ... Cancers 12 (8), 2022, 2020 | 20 | 2020 |
Establishment of a mammary carcinoma cell line from Syrian hamsters treated with N-methyl-N-nitrosourea MA Coburn, S Brueggemann, S Bhatia, B Cheng, BDL Li, XL Li, ... Cancer letters 312 (1), 82-90, 2011 | 14 | 2011 |