| Core transcriptional regulatory circuitry in human embryonic stem cells LA Boyer, TI Lee, MF Cole, SE Johnstone, SS Levine, JP Zucker, ... cell 122 (6), 947-956, 2005 | 5678 | 2005 |
| Control of developmental regulators by Polycomb in human embryonic stem cells TI Lee, RG Jenner, LA Boyer, MG Guenther, SS Levine, RM Kumar, ... Cell 125 (2), 301-313, 2006 | 2738 | 2006 |
| A chromatin landmark and transcription initiation at most promoters in human cells MG Guenther, SS Levine, LA Boyer, R Jaenisch, RA Young Cell 130 (1), 77-88, 2007 | 2332 | 2007 |
| Histone deacetylase is a direct target of valproic acid, a potent anticonvulsant, mood stabilizer, and teratogen CJ Phiel, F Zhang, EY Huang, MG Guenther, MA Lazar, PS Klein Journal of Biological Chemistry 276 (39), 36734-36741, 2001 | 2166 | 2001 |
| Connecting microRNA genes to the core transcriptional regulatory circuitry of embryonic stem cells A Marson, SS Levine, MF Cole, GM Frampton, T Brambrink, S Johnstone, ... cell 134 (3), 521-533, 2008 | 1788 | 2008 |
| Enzymatic activity associated with class II HDACs is dependent on a multiprotein complex containing HDAC3 and SMRT/N-CoR W Fischle, F Dequiedt, MJ Hendzel, MG Guenther, MA Lazar, W Voelter, ... Molecular cell 9 (1), 45-57, 2002 | 961 | 2002 |
| The SMRT and N-CoR corepressors are activating cofactors for histone deacetylase 3 MG Guenther, ORR Barak, MA Lazar Molecular and cellular biology 21 (18), 6091-6101, 2001 | 806 | 2001 |
| Master transcription factors determine cell-type-specific responses to TGF-β signaling AC Mullen, DA Orlando, JJ Newman, J Lovén, RM Kumar, S Bilodeau, ... Cell 147 (3), 565-576, 2011 | 704 | 2011 |
| A core SMRT corepressor complex containing HDAC3 and TBL1, a WD40-repeat protein linked to deafness MG Guenther, WS Lane, W Fischle, E Verdin, MA Lazar, R Shiekhattar Genes & development 14 (9), 1048-1057, 2000 | 592 | 2000 |
| Chromatin structure and gene expression programs of human embryonic and induced pluripotent stem cells MG Guenther, GM Frampton, F Soldner, D Hockemeyer, M Mitalipova, ... Cell stem cell 7 (2), 249-257, 2010 | 572 | 2010 |
| Quantitative ChIP-Seq normalization reveals global modulation of the epigenome DA Orlando, MW Chen, VE Brown, S Solanki, YJ Choi, ER Olson, CC Fritz, ... Cell reports 9 (3), 1163-1170, 2014 | 538 | 2014 |
| Divergent transcription of long noncoding RNA/mRNA gene pairs in embryonic stem cells AA Sigova, AC Mullen, B Molinie, S Gupta, DA Orlando, MG Guenther, ... Proceedings of the National Academy of Sciences 110 (8), 2876-2881, 2013 | 520 | 2013 |
| Derivation of pre-X inactivation human embryonic stem cells under physiological oxygen concentrations CJ Lengner, AA Gimelbrant, JA Erwin, AW Cheng, MG Guenther, ... Cell 141 (5), 872-883, 2010 | 471 | 2010 |
| Global and Hox-specific roles for the MLL1 methyltransferase MG Guenther, RG Jenner, B Chevalier, T Nakamura, CM Croce, ... Proceedings of the National Academy of Sciences 102 (24), 8603-8608, 2005 | 459 | 2005 |
| Nuclear receptor corepressors partner with class II histone deacetylases in a Sin3-independent repression pathway EY Huang, J Zhang, EA Miska, MG Guenther, T Kouzarides, MA Lazar Genes & development 14 (1), 45-54, 2000 | 408 | 2000 |
| Aberrant chromatin at genes encoding stem cell regulators in human mixed-lineage leukemia MG Guenther, LN Lawton, T Rozovskaia, GM Frampton, SS Levine, ... Genes & development 22 (24), 3403-3408, 2008 | 305 | 2008 |
| Proteasomal regulation of nuclear receptor corepressor-mediated repression J Zhang, MG Guenther, RW Carthew, MA Lazar Genes & development 12 (12), 1775-1780, 1998 | 279 | 1998 |
| Histone deacetylase 4 interacts with 53BP1 to mediate the DNA damage response GD Kao, WG McKenna, MG Guenther, RJ Muschel, MA Lazar, TJ Yen The Journal of cell biology 160 (7), 1017-1027, 2003 | 248 | 2003 |
| A SANT motif in the SMRT corepressor interprets the histone code and promotes histone deacetylation J Yu, Y Li, T Ishizuka, MG Guenther, MA Lazar The EMBO journal, 2003 | 246 | 2003 |
| Intrinsic cell-penetrating activity propels Omomyc from proof of concept to viable anti-MYC therapy ME Beaulieu, T Jauset, D Massó-Vallés, S Martínez-Martín, P Rahl, ... Science translational medicine 11 (484), eaar5012, 2019 | 219 | 2019 |