| Stalled spliceosomes are a signal for RNAi-mediated genome defense PA Dumesic, P Natarajan, C Chen, IA Drinnenberg, BJ Schiller, ... Cell 152 (5), 957-968, 2013 | 194 | 2013 |
| Mek1/2 MAPK kinases are essential for Mammalian development, homeostasis, and Raf-induced hyperplasia FA Scholl, PA Dumesic, DI Barragan, K Harada, V Bissonauth, J Charron, ... Developmental cell 12 (4), 615-629, 2007 | 186 | 2007 |
| Product binding enforces the genomic specificity of a yeast polycomb repressive complex PA Dumesic, CM Homer, JJ Moresco, LR Pack, EK Shanle, SM Coyle, ... Cell 160 (1), 204-218, 2015 | 143 | 2015 |
| Erk1/2 MAP kinases are required for epidermal G2/M progression PA Dumesic, FA Scholl, DI Barragan, PA Khavari Journal of Cell Biology 185 (3), 409-422, 2009 | 127 | 2009 |
| Evolutionary persistence of DNA methylation for millions of years after ancient loss of a de novo methyltransferase S Catania, PA Dumesic, H Pimentel, A Nasif, CI Stoddard, JE Burke, ... Cell 180 (2), 263-277. e20, 2020 | 108 | 2020 |
| Mitochondrial TNAP controls thermogenesis by hydrolysis of phosphocreatine Y Sun, JF Rahbani, MP Jedrychowski, CL Riley, S Vidoni, D Bogoslavski, ... Nature 593 (7860), 580-585, 2021 | 95 | 2021 |
| Mek1 alters epidermal growth and differentiation FA Scholl, PA Dumesic, PA Khavari Cancer research 64 (17), 6035-6040, 2004 | 94 | 2004 |
| Combinatorial, site-specific requirement for heterochromatic silencing factors in the elimination of nucleosome-free regions JF Garcia, PA Dumesic, PD Hartley, H El-Samad, HD Madhani Genes & development 24 (16), 1758-1771, 2010 | 81 | 2010 |
| Selective role for Mek1 but not Mek2 in the induction of epidermal neoplasia FA Scholl, PA Dumesic, DI Barragan, K Harada, J Charron, PA Khavari Cancer research 69 (9), 3772-3778, 2009 | 60 | 2009 |
| Effects of active MEK1 expression in vivo FA Scholl, PA Dumesic, PA Khavari Cancer letters 230 (1), 1-5, 2005 | 60 | 2005 |
| An evolutionarily conserved uORF regulates PGC1α and oxidative metabolism in mice, flies, and bluefin tuna PA Dumesic, DF Egan, P Gut, MT Tran, A Parisi, N Chatterjee, ... Cell metabolism 30 (1), 190-200. e6, 2019 | 55 | 2019 |
| SnapShot: Regulation and biology of PGC-1α PR Jannig, PA Dumesic, BM Spiegelman, JL Ruas Cell 185 (8), 1444-1444. e1, 2022 | 54 | 2022 |
| Integrated Activity and Genetic Profiling of Secreted Peptidases in Cryptococcus neoformans Reveals an Aspartyl Peptidase Required for Low pH Survival and … SC Clarke, PA Dumesic, CM Homer, AJ O’Donoghue, F La Greca, ... PLoS pathogens 12 (12), e1006051, 2016 | 42 | 2016 |
| Ers1 links HP1 to RNAi M Rougemaille, S Braun, S Coyle, PA Dumesic, JF Garcia, RS Isaac, ... Proceedings of the National Academy of Sciences 109 (28), 11258-11263, 2012 | 38 | 2012 |
| Isolation of extracellular fluids reveals novel secreted bioactive proteins from muscle and fat tissues MJ Mittenbühler, MP Jedrychowski, JG Van Vranken, HG Sprenger, ... Cell Metabolism 35 (3), 535-549. e7, 2023 | 33 | 2023 |
| Mek1/2 gene dosage determines tissue response to oncogenic Ras signaling in the skin FA Scholl, PA Dumesic, DI Barragan, J Charron, PA Khavari Oncogene 28 (12), 1485-1495, 2009 | 32 | 2009 |
| Recognizing the enemy within: licensing RNA-guided genome defense PA Dumesic, HD Madhani Trends in biochemical sciences 39 (1), 25-34, 2014 | 28 | 2014 |
| Dynamic changes in chromatin accessibility, altered adipogenic gene expression, and total versus de novo fatty acid synthesis in subcutaneous adipose stem cells of normal … KL Leung, S Sanchita, CT Pham, BA Davis, M Okhovat, X Ding, ... Clinical epigenetics 12, 1-16, 2020 | 24 | 2020 |
| The spliceosome as a transposon sensor PA Dumesic, HD Madhani RNA biology 10 (11), 1653-1660, 2013 | 20 | 2013 |
| ATP hydrolysis by the SNF2 domain of Dnmt5 is coupled to both specific recognition and modification of hemimethylated DNA PA Dumesic, CI Stoddard, S Catania, GJ Narlikar, HD Madhani Molecular Cell 79 (1), 127-139. e4, 2020 | 17 | 2020 |
Hiten MadhaniProfessor and Vice Chair, Dept. of Biochemistry and Biophysics, UCSFCorreu electrònic verificat a ucsf.edu
