The SARS-CoV-2 variants associated with infections in India, B. 1.617, show enhanced spike cleavage by furin TP Peacock, CM Sheppard, JC Brown, N Goonawardane, J Zhou, ... BioRxiv, 2021.05. 28.446163, 2021 | 97 | 2021 |
ANP32 proteins are essential for influenza virus replication in human cells E Staller, CM Sheppard, PJ Neasham, B Mistry, TP Peacock, DH Goldhill, ... Journal of virology 93 (17), 10.1128/jvi. 00217-19, 2019 | 85 | 2019 |
RASSF7 is a member of a new family of RAS association domain–containing proteins and is required for completing mitosis V Sherwood, R Manbodh, C Sheppard, AD Chalmers Molecular biology of the cell 19 (4), 1772-1782, 2008 | 79 | 2008 |
Archaeal TFEα/β is a hybrid of TFIIE and the RNA polymerase III subcomplex hRPC62/39 F Blombach, E Salvadori, T Fouqueau, J Yan, J Reimann, C Sheppard, ... Elife 4, e08378, 2015 | 59 | 2015 |
Structural and mechanistic basis for the inhibition of Escherichia coli RNA polymerase by T7 Gp2 E James, M Liu, C Sheppard, V Mekler, B Cámara, B Liu, P Simpson, ... Molecular cell 47 (5), 755-766, 2012 | 47 | 2012 |
Host determinants of influenza RNA synthesis TP Peacock, CM Sheppard, E Staller, WS Barclay Annual review of virology 6 (1), 215-233, 2019 | 44 | 2019 |
Creating resistance to avian influenza infection through genome editing of the ANP32 gene family A Idoko-Akoh, DH Goldhill, CM Sheppard, D Bialy, JL Quantrill, ... Nature communications 14 (1), 6136, 2023 | 43 | 2023 |
Molecular mechanism of transcription inhibition by phage T7 gp2 protein V Mekler, L Minakhin, C Sheppard, S Wigneshweraraj, K Severinov Journal of molecular biology 413 (5), 1016-1027, 2011 | 40 | 2011 |
The SARS-CoV-2 variants associated with infections in India TP Peacock, CM Sheppard, JC Brown, N Goonawardane, J Zhou, ... B 1, 1-10, 2021 | 36 | 2021 |
A bacteriophage transcription regulator inhibits bacterial transcription initiation by σ-factor displacement B Liu, A Shadrin, C Sheppard, V Mekler, Y Xu, K Severinov, S Matthews, ... Nucleic acids research 42 (7), 4294-4305, 2014 | 33 | 2014 |
Key Roles of the Downstream Mobile Jaw of Escherichia coli RNA Polymerase in Transcription Initiation A Drennan, M Kraemer, M Capp, T Gries, E Ruff, C Sheppard, ... Biochemistry 51 (47), 9447-9459, 2012 | 33 | 2012 |
Repression of RNA polymerase by the archaeo-viral regulator ORF145/RIP C Sheppard, F Blombach, A Belsom, S Schulz, T Daviter, K Smollett, ... Nature Communications 7 (1), 13595, 2016 | 27 | 2016 |
The C-terminal LCAR of host ANP32 proteins interacts with the influenza A virus nucleoprotein to promote the replication of the viral RNA genome F Wang, CM Sheppard, B Mistry, E Staller, WS Barclay, JM Grimes, ... Nucleic acids research 50 (10), 5713-5725, 2022 | 26 | 2022 |
Mammalian ANP32A and ANP32B proteins drive differential polymerase adaptations in avian influenza virus TP Peacock, CM Sheppard, MG Lister, E Staller, R Frise, OC Swann, ... Journal of virology 97 (5), e00213-23, 2023 | 24 | 2023 |
Conformational heterogeneity and bubble dynamics in single bacterial transcription initiation complexes D Duchi, K Gryte, NC Robb, Z Morichaud, C Sheppard, K Brodolin, ... Nucleic acids research 46 (2), 677-688, 2018 | 21 | 2018 |
Inhibition of Escherichia coli RNAp by T7 Gp2 protein: role of negatively charged strip of amino acid residues in Gp2 C Sheppard, B Cámara, A Shadrin, N Akulenko, M Liu, G Baldwin, ... Journal of molecular biology 407 (5), 623-632, 2011 | 21 | 2011 |
Structure and mechanisms of viral transcription factors in archaea C Sheppard, F Werner Extremophiles 21 (5), 829-838, 2017 | 19 | 2017 |
An influenza A virus can evolve to use human ANP32E through altering polymerase dimerization CM Sheppard, DH Goldhill, OC Swann, E Staller, R Penn, OK Platt, ... Nature communications 14 (1), 6135, 2023 | 18 | 2023 |
Structures of H5N1 influenza polymerase with ANP32B reveal mechanisms of genome replication and host adaptation E Staller, L Carrique, OC Swann, H Fan, JR Keown, CM Sheppard, ... Nature Communications 15 (1), 4123, 2024 | 15 | 2024 |
Substitutions in the Escherichia coli RNA polymerase inhibitor T7 Gp2 that allow inhibition of transcription when the primary interaction interface between Gp2 and … A Shadrin, C Sheppard, K Severinov, S Matthews, S Wigneshweraraj Microbiology 158 (11), 2753-2764, 2012 | 13 | 2012 |