| Recent advances in urea-and thiourea-containing compounds: focus on innovative approaches in medicinal chemistry and organic synthesis R Ronchetti, G Moroni, A Carotti, A Gioiello, E Camaioni RSC Medicinal Chemistry 12 (7), 1046-1064, 2021 | 133 | 2021 |
| Structural insights into monoamine oxidase inhibitory potency and selectivity of 7-substituted coumarins from ligand-and target-based approaches M Catto, O Nicolotti, F Leonetti, A Carotti, AD Favia, R Soto-Otero, ... Journal of medicinal chemistry 49 (16), 4912-4925, 2006 | 133 | 2006 |
| Natural and synthetic geiparvarins are strong and selective MAO-B inhibitors. Synthesis and SAR studies A Carotti, A Carrieri, S Chimichi, M Boccalini, B Cosimelli, C Gnerre, ... Bioorganic & Medicinal Chemistry Letters 12 (24), 3551-3555, 2002 | 109 | 2002 |
| Extending SAR of bile acids as FXR ligands: Discovery of 23-N-(carbocinnamyloxy)-3α,7α-dihydroxy-6α-ethyl-24-nor-5β-cholan-23-amine A Gioiello, A Macchiarulo, A Carotti, P Filipponi, G Costantino, G Rizzo, ... Bioorganic & medicinal chemistry 19 (8), 2650-2658, 2011 | 69 | 2011 |
| Discovery of 3α, 7α, 11β-trihydroxy-6α-ethyl-5β-cholan-24-oic acid (TC-100), a novel bile acid as potent and highly selective FXR agonist for enterohepatic disorders R Pellicciari, D Passeri, F De Franco, S Mostarda, P Filipponi, C Colliva, ... Journal of Medicinal Chemistry 59 (19), 9201-9214, 2016 | 62 | 2016 |
| 4, 5-Diarylisoxazol-3-carboxylic acids: A new class of leukotriene biosynthesis inhibitors potentially targeting 5-lipoxygenase-activating protein (FLAP) E Banoglu, E Çelikoğlu, S Völker, A Olgaç, J Gerstmeier, U Garscha, ... European Journal of Medicinal Chemistry 113, 1-10, 2016 | 62 | 2016 |
| Targeting Wnt-driven cancers: Discovery of novel tankyrase inhibitors M Ferri, P Liscio, A Carotti, S Asciutti, R Sardella, A Macchiarulo, ... European Journal of Medicinal Chemistry 142, 506-522, 2017 | 60 | 2017 |
| Fluorinated benzyloxyphenyl piperidine-4-carboxamides with dual function against thrombosis: inhibitors of factor Xa and platelet aggregation M de Candia, F Liantonio, A Carotti, R De Cristofaro, C Altomare Journal of medicinal chemistry 52 (4), 1018-1028, 2009 | 60 | 2009 |
| Pyrazole [3, 4-e][1, 4] thiazepin-7-one derivatives as a novel class of Farnesoid X Receptor (FXR) agonists M Marinozzi, A Carotti, E Sansone, A Macchiarulo, E Rosatelli, R Sardella, ... Bioorganic & medicinal chemistry 20 (11), 3429-3445, 2012 | 56 | 2012 |
| An integrated approach to ligand-and structure-based drug design: development and application to a series of serine protease inhibitors O Nicolotti, TF Miscioscia, A Carotti, F Leonetti, A Carotti Journal of chemical information and modeling 48 (6), 1211-1226, 2008 | 55 | 2008 |
| Beyond bile acids: targeting Farnesoid X Receptor (FXR) with natural and synthetic ligands A Carotti, M Marinozzi, C Custodi, B Cerra, R Pellicciari, A Gioiello, ... Current topics in medicinal chemistry 14 (19), 2129-2142, 2014 | 54 | 2014 |
| Synthesis and monoamine oxidase inhibitory activity of new pyridazine-, pyrimidine-and 1, 2, 4-triazine-containing tricyclic derivatives A Carotti, M Catto, F Leonetti, F Campagna, R Soto-Otero, ... Journal of medicinal chemistry 50 (22), 5364-5371, 2007 | 52 | 2007 |
| High affinity central benzodiazepine receptor ligands: Synthesis and structure–activity relationship studies of a new series of pyrazolo [4, 3-c] quinolin-3-ones L Savini, P Massarelli, C Nencini, C Pellerano, G Biggio, A Maciocco, ... Bioorganic & medicinal chemistry 6 (4), 389-399, 1998 | 50 | 1998 |
| Mechanistic considerations of enantiorecognition on novel Cinchona alkaloid-based zwitterionic chiral stationary phases from the aspect of the separation of trans-paroxetine … N Grecsó, M Kohout, A Carotti, R Sardella, B Natalini, F Fülöp, W Lindner, ... Journal of Pharmaceutical and Biomedical Analysis 124, 164-173, 2016 | 47 | 2016 |
| Ester derivatives of annulated tetrahydroazocines: A new class of selective acetylcholinesterase inhibitors A Carotti, M de Candia, M Catto, TN Borisova, AV Varlamov, ... Bioorganic & medicinal chemistry 14 (21), 7205-7212, 2006 | 46 | 2006 |
| α-Amino-β-carboxymuconate-ε-semialdehyde decarboxylase (ACMSD) inhibitors as novel modulators of de novo nicotinamide adenine dinucleotide (NAD+) biosynthesis R Pellicciari, P Liscio, N Giacchè, F De Franco, A Carotti, J Robertson, ... Journal of medicinal chemistry 61 (3), 745-759, 2018 | 45 | 2018 |
| Design, Synthesis, Crystallographic Studies, and Preliminary Biological Appraisal of New Substituted Triazolo[4,3-b]pyridazin-8-amine Derivatives as Tankyrase … P Liscio, A Carotti, S Asciutti, T Karlberg, D Bellocchi, L Llacuna, ... Journal of medicinal chemistry 57 (6), 2807-2812, 2014 | 45 | 2014 |
| Computational studies in enantioselective liquid chromatography: forty years of evolution in docking-and molecular dynamics-based simulations R Sardella, E Camaioni, A Macchiarulo, A Gioiello, M Marinozzi, A Carotti TrAC Trends in Analytical Chemistry 122, 115703, 2020 | 43 | 2020 |
| From polypharmacology to target specificity: the case of PARP inhibitors P Liscio, E Camaioni, A Carotti, R Pellicciari, A Macchiarulo Current Topics in Medicinal Chemistry 13 (23), 2939-2954, 2013 | 42 | 2013 |
| The natural mutation by deletion of Lys9 in the thrombin A‐chain affects the pKa value of catalytic residues, the overall enzyme's stability and conformational transitions … R De Cristofaro, A Carotti, S Akhavan, R Palla, F Peyvandi, C Altomare, ... The FEBS journal 273 (1), 159-169, 2006 | 40 | 2006 |
Antonio MacchiaruloFull Professor, University of PerugiaCorreu electrònic verificat a chimfarm.unipg.it