A robust pipeline for rapid production of versatile nanobody repertoires PC Fridy, Y Li, S Keegan, MK Thompson, I Nudelman, JF Scheid, ... Nature methods 11 (12), 1253-1260, 2014 | 514 | 2014 |
A conserved family of enzymes that phosphorylate inositol hexakisphosphate S Mulugu, W Bai, PC Fridy, RJ Bastidas, JC Otto, DE Dollins, TA Haystead, ... Science 316 (5821), 106-109, 2007 | 291 | 2007 |
A strategy for dissecting the architectures of native macromolecular assemblies Y Shi, R Pellarin, PC Fridy, J Fernandez-Martinez, MK Thompson, Y Li, ... Nature methods 12 (12), 1135-1138, 2015 | 148 | 2015 |
Structural analysis and detection of biological inositol pyrophosphates reveal that the family of VIP/diphosphoinositol pentakisphosphate kinases are 1/3-kinases H Lin, PC Fridy, AA Ribeiro, JH Choi, DK Barma, G Vogel, JR Falck, ... Journal of Biological Chemistry 284 (3), 1863-1872, 2009 | 145 | 2009 |
Cloning and characterization of two human VIP1-like inositol hexakisphosphate and diphosphoinositol pentakisphosphate kinases PC Fridy, JC Otto, DE Dollins, JD York Journal of Biological Chemistry 282 (42), 30754-30762, 2007 | 137 | 2007 |
Characterization of a selective inhibitor of inositol hexakisphosphate kinases U Padmanabhan, DE Dollins, PC Fridy, JD York, CP Downes Journal of Biological Chemistry 284 (16), 10571-10582, 2009 | 121 | 2009 |
Highly synergistic combinations of nanobodies that target SARS-CoV-2 and are resistant to escape FD Mast, PC Fridy, NE Ketaren, J Wang, EY Jacobs, JP Olivier, T Sanyal, ... Elife 10, e73027, 2021 | 59 | 2021 |
Vip1 is a kinase and pyrophosphatase switch that regulates inositol diphosphate signaling DE Dollins, W Bai, PC Fridy, JC Otto, JL Neubauer, SG Gattis, KPM Mehta, ... Proceedings of the National Academy of Sciences 117 (17), 9356-9364, 2020 | 56 | 2020 |
Ultrasensitive detection of circulating LINE-1 ORF1p as a specific multicancer biomarker MS Taylor, C Wu, PC Fridy, SJ Zhang, Y Senussi, JC Wolters, T Cajuso, ... Cancer discovery 13 (12), 2532-2547, 2023 | 42 | 2023 |
Supervillin binding to myosin II and synergism with anillin are required for cytokinesis TC Smith, PC Fridy, Y Li, S Basil, S Arjun, RM Friesen, J Leszyk, BT Chait, ... Molecular Biology of the Cell 24 (23), 3603-3619, 2013 | 41 | 2013 |
Engineered high-affinity nanobodies recognizing staphylococcal Protein A and suitable for native isolation of protein complexes PC Fridy, MK Thompson, NE Ketaren, MP Rout Analytical biochemistry 477, 92-94, 2015 | 23 | 2015 |
Optimizing selection of large animals for antibody production by screening immune response to standard vaccines MK Thompson, PC Fridy, S Keegan, BT Chait, D Fenyö, MP Rout Journal of immunological methods 430, 56-60, 2016 | 21 | 2016 |
Biochemical analysis of inositol phosphate kinases JC Otto, S Mulugu, PC Fridy, ST Chiou, BN Armbruster, AA Ribeiro, ... Methods in enzymology 434, 171-185, 2007 | 12 | 2007 |
Expanding and improving nanobody repertoires using a yeast display method: Targeting SARS-CoV-2 FR Cross, PC Fridy, NE Ketaren, FD Mast, S Li, JP Olivier, K Pecani, ... Journal of Biological Chemistry 299 (3), 2023 | 10 | 2023 |
Nanobody repertoires for exposing vulnerabilities of SARS-CoV-2 FD Mast, PC Fridy, NE Ketaren, J Wang, EY Jacobs, JP Olivier, T Sanyal, ... BioRxiv, 2021 | 10 | 2021 |
Proteomic elucidation of the targets and primary functions of the picornavirus 2A protease AA Serganov, Y Udi, ME Stein, V Patel, PC Fridy, CM Rice, M Saeed, ... Journal of Biological Chemistry 298 (6), 2022 | 9 | 2022 |
Nanobody repertoire generated against the spike protein of ancestral SARS-CoV-2 remains efficacious against the rapidly evolving virus NE Ketaren, FD Mast, PC Fridy, JP Olivier, T Sanyal, A Sali, BT Chait, ... Elife 12, RP89423, 2024 | 5 | 2024 |
Nanobodies: from high-throughput identification to therapeutic development PC Fridy, MP Rout, NE Ketaren Molecular & Cellular Proteomics, 100865, 2024 | 1 | 2024 |
A new generation of nanobody research tools using improved mass spectrometry-based discovery methods PC Fridy, RJ Farrell, KR Molloy, S Keegan, J Wang, EY Jacobs, Y Li, ... Journal of Biological Chemistry 300 (9), 107623, 2024 | 1 | 2024 |
Unique binding and stabilization mechanisms employed by and engineered into nanobodies NE Ketaren, PC Fridy, V Malashkevich, T Sanyal, M Brillantes, ... bioRxiv, 2023.10. 22.563475, 2023 | 1 | 2023 |