| Long-term clinical efficacy of grass-pollen immunotherapy SR Durham, SM Walker, EM Varga, MR Jacobson, F O'Brien, W Noble, ... New England Journal of Medicine 341 (7), 468-475, 1999 | 1869 | 1999 |
| Tau phosphorylation: the therapeutic challenge for neurodegenerative disease DP Hanger, BH Anderton, W Noble Trends in molecular medicine 15 (3), 112-119, 2009 | 1202 | 2009 |
| Roles of tau protein in health and disease T Guo, W Noble, DP Hanger Acta neuropathologica 133, 665-704, 2017 | 1093 | 2017 |
| Inhibition of glycogen synthase kinase-3 by lithium correlates with reduced tauopathy and degeneration in vivo W Noble, E Planel, C Zehr, V Olm, J Meyerson, F Suleman, K Gaynor, ... Proceedings of the national academy of sciences 102 (19), 6990-6995, 2005 | 961 | 2005 |
| Physiological release of endogenous tau is stimulated by neuronal activity AM Pooler, EC Phillips, DHW Lau, W Noble, DP Hanger EMBO reports 14 (4), 389-394, 2013 | 703 | 2013 |
| Cdk5 is a key factor in tau aggregation and tangle formation in vivo W Noble, V Olm, K Takata, E Casey, O Mary, J Meyerson, K Gaynor, ... Neuron 38 (4), 555-565, 2003 | 596 | 2003 |
| The importance of tau phosphorylation for neurodegenerative diseases W Noble, DP Hanger, CCJ Miller, S Lovestone Frontiers in neurology 4, 83, 2013 | 527 | 2013 |
| A comparison of recombinant hirudin with heparin for the treatment of acute coronary syndromes Global Use of Strategies to Open Occluded Coronary Arteries (GUSTO) IIb ... New England Journal of Medicine 335 (11), 775-782, 1996 | 447 | 1996 |
| Astrocytes are important mediators of Aβ-induced neurotoxicity and tau phosphorylation in primary culture CJ Garwood, AM Pooler, J Atherton, DP Hanger, W Noble Cell death & disease 2 (6), e167-e167, 2011 | 432 | 2011 |
| International, randomized, controlled trial of lamifiban (a platelet glycoprotein IIb/IIIa inhibitor), heparin, or both in unstable angina E Topol, R Califf, F Van de Werf, R Diaz, E Paolasso, P Aylward, J Simes, ... Circulation 97 (24), 2386-2395, 1998 | 430 | 1998 |
| The ER-mitochondria tethering complex VAPB-PTPIP51 regulates autophagy P Gomez-Suaga, S Paillusson, R Stoica, W Noble, DP Hanger, CCJ Miller Current Biology 27 (3), 371-385, 2017 | 386 | 2017 |
| α-Synuclein binds to the ER–mitochondria tethering protein VAPB to disrupt Ca2+ homeostasis and mitochondrial ATP production S Paillusson, P Gomez-Suaga, R Stoica, D Little, P Gissen, MJ Devine, ... Acta neuropathologica 134, 129-149, 2017 | 366 | 2017 |
| ALS/FTD‐associated FUS activates GSK‐3β to disrupt the VAPB–PTPIP 51 interaction and ER–mitochondria associations R Stoica, S Paillusson, P Gomez‐Suaga, JC Mitchell, DHW Lau, EH Gray, ... EMBO reports 17 (9), 1326-1342, 2016 | 276 | 2016 |
| Clusterin regulates β-amyloid toxicity via Dickkopf-1-driven induction of the wnt–PCP–JNK pathway R Killick, EM Ribe, R Al-Shawi, B Malik, C Hooper, C Fernandes, ... Molecular psychiatry 19 (1), 88-98, 2014 | 274 | 2014 |
| A role for tau at the synapse in Alzheimer's disease pathogenesis AM Pooler, W Noble, DP Hanger Neuropharmacology 76, 1-8, 2014 | 246 | 2014 |
| Tyrosine 394 is phosphorylated in Alzheimer's paired helical filament tau and in fetal tau with c-Abl as the candidate tyrosine kinase P Derkinderen, TME Scales, DP Hanger, KY Leung, HL Byers, MA Ward, ... Journal of Neuroscience 25 (28), 6584-6593, 2005 | 236 | 2005 |
| Presenilin redistribution associated with aberrant cholesterol transport enhances β-amyloid production in vivo M Burns, K Gaynor, V Olm, M Mercken, J LaFrancois, L Wang, ... Journal of Neuroscience 23 (13), 5645-5649, 2003 | 228 | 2003 |
| Tau phosphorylation affects its axonal transport and degradation T Rodríguez-Martín, I Cuchillo-Ibáñez, W Noble, F Nyenya, BH Anderton, ... Neurobiology of aging 34 (9), 2146-2157, 2013 | 226 | 2013 |
| Collapsin response mediator protein‐2 hyperphosphorylation is an early event in Alzheimer’s disease progression AR Cole, W Noble, L Aalten, F Plattner, R Meimaridou, D Hogan, M Taylor, ... Journal of neurochemistry 103 (3), 1132-1144, 2007 | 205 | 2007 |
| Molecular motors implicated in the axonal transport of tau and α-synuclein MA Utton, WJ Noble, JE Hill, BH Anderton, DP Hanger Journal of cell science 118 (20), 4645-4654, 2005 | 194 | 2005 |
