Increased level of active GSK‐3β in Alzheimer’s disease and accumulation in argyrophilic grains and in neurones at different stages of neurofibrillary degeneration K Leroy, Z Yilmaz, JP Brion Neuropathology and applied neurobiology 33 (1), 43-55, 2007 | 472 | 2007 |
Alzheimer's disease-like tau neuropathology leads to memory deficits and loss of functional synapses in a novel mutated tau transgenic mouse without any motor deficits K Schindowski, A Bretteville, K Leroy, S Bégard, JP Brion, M Hamdane, ... The American journal of pathology 169 (2), 599-616, 2006 | 464 | 2006 |
Developmental expression and localization of glycogen synthase kinase-3β in rat brain K Leroy, JP Brion Journal of chemical neuroanatomy 16 (4), 279-293, 1999 | 295 | 1999 |
Clusterin regulates β-amyloid toxicity via Dickkopf-1-driven induction of the wnt–PCP–JNK pathway R Killick, EM Ribe, R Al-Shawi, B Malik, C Hooper, C Fernandes, ... Molecular psychiatry 19 (1), 88-98, 2014 | 274 | 2014 |
Mutations in tau reduce its microtubule binding properties in intact cells and affect its phosphorylation R Dayanandan, M Van Slegtenhorst, TGA Mack, L Ko, SH Yen, K Leroy, ... FEBS letters 446 (2-3), 228-232, 1999 | 269 | 1999 |
Hallmarks of Alzheimer’s disease in stem-cell-derived human neurons transplanted into mouse brain I Espuny-Camacho, AM Arranz, M Fiers, A Snellinx, K Ando, S Munck, ... Neuron 93 (5), 1066-1081. e8, 2017 | 241 | 2017 |
Tyrosine 394 is phosphorylated in Alzheimer's paired helical filament tau and in fetal tau with c-Abl as the candidate tyrosine kinase P Derkinderen, TME Scales, DP Hanger, KY Leung, HL Byers, MA Ward, ... Journal of Neuroscience 25 (28), 6584-6593, 2005 | 236 | 2005 |
The active form of glycogen synthase kinase-3β is associated with granulovacuolar degeneration in neurons in Alzheimer's disease K Leroy, A Boutajangout, M Authelet, JR Woodgett, BH Anderton, JP Brion Acta neuropathologica 103, 91-99, 2002 | 232 | 2002 |
Lack of tau proteins rescues neuronal cell death and decreases amyloidogenic processing of APP in APP/PS1 mice K Leroy, K Ando, V Laporte, R Dedecker, V Suain, M Authelet, C Héraud, ... The American journal of pathology 181 (6), 1928-1940, 2012 | 195 | 2012 |
Neurofibrillary tangles and tau phosphorylation JP Brion, BH Anderton, M Authelet, R Dayanandan, K Leroy, S Lovestone, ... Biochemical Society Symposia 67, 81-88, 2001 | 174 | 2001 |
Early axonopathy preceding neurofibrillary tangles in mutant tau transgenic mice K Leroy, A Bretteville, K Schindowski, E Gilissen, M Authelet, R De Decker, ... The American journal of pathology 171 (3), 976-992, 2007 | 160 | 2007 |
Deletion of Irs2 reduces amyloid deposition and rescues behavioural deficits in APP transgenic mice R Killick, G Scales, K Leroy, M Causevic, C Hooper, EE Irvine, ... Biochemical and biophysical research communications 386 (1), 257-262, 2009 | 155 | 2009 |
Sites of phosphorylation in tau and factors affecting their regulation BH Anderton, J Betts, WP Blackstock, JP Brion, S Chapman, J Connell, ... Biochemical Society Symposia 67, 73-80, 2001 | 142 | 2001 |
Amyloid-β pathology enhances pathological fibrillary tau seeding induced by Alzheimer PHF in vivo C Vergara, S Houben, V Suain, Z Yilmaz, R De Decker, V Vanden Dries, ... Acta neuropathologica 137, 397-412, 2019 | 113 | 2019 |
Phrenic motor neuron degeneration compromises phrenic axonal circuitry and diaphragm activity in a unilateral cervical contusion model of spinal cord injury C Nicaise, TJ Hala, DM Frank, JL Parker, M Authelet, K Leroy, JP Brion, ... Experimental neurology 235 (2), 539-552, 2012 | 108 | 2012 |
Lithium treatment arrests the development of neurofibrillary tangles in mutant tau transgenic mice with advanced neurofibrillary pathology K Leroy, K Ando, C Héraud, Z Yilmaz, M Authelet, JM Boeynaems, L Buée, ... Journal of Alzheimer's Disease 19 (2), 705-719, 2010 | 108 | 2010 |
Mint2/X11‐like colocalizes with the Alzheimer's disease amyloid precursor protein and is associated with neuritic plaques in Alzheimer's disease DM McLoughlin, NG Irving, J Brownlees, JP Brion, K Leroy, CCJ Miller European journal of neuroscience 11 (6), 1988-1994, 1999 | 101 | 1999 |
Expression of tau mRNA and soluble tau isoforms in affected and non-affected brain areas in Alzheimer's disease A Boutajangout, A Boom, K Leroy, JP Brion FEBS letters 576 (1-2), 183-189, 2004 | 97 | 2004 |
Accelerated human mutant tau aggregation by knocking out murine tau in a transgenic mouse model K Ando, K Leroy, C Héraud, Z Yilmaz, M Authelet, V Suain, R De Decker, ... The American journal of pathology 178 (2), 803-816, 2011 | 82 | 2011 |
Degeneration of phrenic motor neurons induces long-term diaphragm deficits following mid-cervical spinal contusion in mice C Nicaise, R Putatunda, TJ Hala, KA Regan, DM Frank, JP Brion, K Leroy, ... Journal of neurotrauma 29 (18), 2748-2760, 2012 | 81 | 2012 |