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Wee Loong Chin
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Sensitization to immune checkpoint blockade through activation of a STAT1/NK axis in the tumor microenvironment
RM Zemek, E De Jong, WL Chin, IS Schuster, VS Fear, TH Casey, ...
Science translational medicine 11 (501), eaav7816, 2019
2122019
Sensitizing the tumor microenvironment to immune checkpoint therapy
RM Zemek, WL Chin, AK Nowak, MJ Millward, RA Lake, WJ Lesterhuis
Frontiers in immunology 11, 223, 2020
692020
Temporally restricted activation of IFNβ signaling underlies response to immune checkpoint therapy in mice
RM Zemek, WL Chin, VS Fear, B Wylie, TH Casey, C Forbes, CM Tilsed, ...
Nature Communications 13 (1), 4895, 2022
332022
A phase II trial of single oral FGF inhibitor, AZD4547, as second or third line therapy in malignant pleural mesothelioma
WS Lam, J Creaney, FK Chen, WL Chin, S Muruganandan, ...
Lung Cancer 140, 87-92, 2020
252020
Changes in expression of PD-L1 on peripheral T cells in patients with melanoma and lung cancer treated with PD-1 inhibitors
SJ Dart, AM Cook, MJ Millward, AM McDonnell, WL Chin, MU Hakeem, ...
Scientific reports 11 (1), 15312, 2021
192021
Characterising the binding specificities of the subunits associated with the KMT2/Set1 histone lysine methyltransferase
BL Murton, WL Chin, CP Ponting, LS Itzhaki
Journal of molecular biology 398 (4), 481-488, 2010
182010
CD4+ T cells drive an inflammatory, TNF-α/IFN-rich tumor microenvironment responsive to chemotherapy
CM Tilsed, N Principe, J Kidman, WL Chin, MLO Morales, RM Zemek, ...
Cell Reports 41 (13), 2022
152022
Comprehensive testing of chemotherapy and immune checkpoint blockade in preclinical cancer models identifies additive combinations
N Principe, WJ Aston, DE Hope, CM Tilsed, SA Fisher, L Boon, IM Dick, ...
Frontiers in immunology 13, 872295, 2022
112022
Immune checkpoint inhibitor therapy for malignant pleural mesothelioma
AK Nowak, WL Chin, S Keam, A Cook
Lung Cancer 162, 162-168, 2021
102021
UV1 telomerase vaccine with ipilimumab and nivolumab as second line treatment for pleural mesothelioma–A phase II randomised trial
VD Haakensen, ÅK Öjlert, S Thunold, S Farooqi, AK Nowak, WL Chin, ...
European Journal of Cancer 202, 113973, 2024
92024
Sensitization to immune checkpoint blockade through activation of a STAT1/NK axis in the tumor microenvironment. Sci. Transl. Med. 11, eaav7816
RM Zemek, E De Jong, WL Chin, IS Schuster, VS Fear, TH Casey, ...
82019
Sensitization to immune checkpoint blockade through activation of a STAT1/NK axis in the tumor microenvironment. Sci Transl Med
RM Zemek, E De Jong, WL Chin, IS Schuster, VS Fear, TH Casey, ...
72019
Functional genomics in cancer immunotherapy: computational approaches for biomarker and drug discovery
WL Chin, RM Zemek, WJ Lesterhuis, T Lassmann
Molecular Systems Design & Engineering 4 (4), 689-700, 2019
72019
SampleExplorer: using language models to discover relevant transcriptome data
WL Chin, T Lassmann
Bioinformatics 41 (1), btae759, 2025
12025
LBA99 First survival data from the NIPU trial: A randomised, open-label, phase II study evaluating nivolumab and ipilimumab combined with UV1 vaccination as second-line …
A Helland, VD Haakensen, AK Ojlert, SMH Thunold, AK Nowak, WL Chin, ...
Annals of Oncology 34, S1337, 2023
12023
Coupling of response biomarkers between tumor and peripheral blood in patients undergoing chemoimmunotherapy
WL Chin, AM Cook, J Chee, N Principe, TS Hoang, J Kidman, KPW Hmon, ...
Cell Reports Medicine 6 (1), 2025
2025
Mesothelioma survival prediction based on a six-gene transcriptomic signature
K Behrouzfar, SE Mutsaers, WL Chin, K Patrick, IT Ng, FJ Pixley, ...
Iscience 27 (10), 2024
2024
448 (PB436): Deletion of SUZ12 improves cancer cell immunogenicity
MLO Morales, K Farley, C Forbes, WL Chin, J Lu, SM Lansley, C Leslie, ...
European Journal of Cancer 211, 114956, 2024
2024
1917P Updated survival and vaccine response from the NIPU trial: A randomised, phase II study evaluating nivolumab and ipilimumab with or without UV1 vaccination in patients …
VD Haakensen, ÅK Öjlert, W Kefi, SMH Thunold, SJ Farooqi, AK Nowak, ...
Annals of Oncology 35, S1116, 2024
2024
Time-course RNAseq data of murine AB1 mesothelioma and Renca renal cancer following immune checkpoint therapy
WL Chin, RM Zemek, CM Tilsed, ARR Forrest, VS Fear, C Forbes, L Boon, ...
Scientific Data 11 (1), 448, 2024
2024
En aquests moments el sistema no pot dur a terme l'operació. Torneu-ho a provar més tard.
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