| Interleukin-3-induced phosphorylation of BAD through the protein kinase Akt L Peso, M González-Garcıa, C Page, R Herrera, G Nunez Science 278 (5338), 687-689, 1997 | 2929 | 1997 |
| Nod1, an Apaf-1-like activator of caspase-9 and nuclear factor-κB N Inohara, T Koseki, L Del Peso, Y Hu, C Yee, S Chen, R Carrio, J Merino, ... Journal of Biological Chemistry 274 (21), 14560-14567, 1999 | 988 | 1999 |
| An induced proximity model for NF-κB activation in the Nod1/RICK and RIP signaling pathways N Inohara, T Koseki, J Lin, L Del Peso, PC Lucas, FF Chen, Y Ogura, ... Journal of Biological Chemistry 275 (36), 27823-27831, 2000 | 733 | 2000 |
| Hypoxia promotes glycogen accumulation through hypoxia inducible factor (HIF)-mediated induction of glycogen synthase 1 N Pescador, D Villar, D Cifuentes, M Garcia-Rocha, A Ortiz-Barahona, ... PloS one 5 (3), e9644, 2010 | 317 | 2010 |
| RICK, a novel protein kinase containing a caspase recruitment domain, interacts with CLARP and regulates CD95-mediated apoptosis N Inohara, L Del Peso, T Koseki, S Chen, G Núñez Journal of Biological Chemistry 273 (20), 12296-12300, 1998 | 300 | 1998 |
| Hypoxia induces the activation of the phosphatidylinositol 3-kinase/Akt cell survival pathway in PC12 cells: protective role in apoptosis M Alvarez-Tejado, S Naranjo-Suárez, C Jiménez, AC Carrera, ... Journal of Biological Chemistry 276 (25), 22368-22374, 2001 | 298 | 2001 |
| Identification of a functional hypoxia-responsive element that regulates the expression of the egl nine homologue 3 (egln3/phd3) gene N Pescador, Y Cuevas, S Naranjo, M Alcaide, D Villar, MO Landázuri, ... Biochemical Journal 390 (1), 189-197, 2005 | 290 | 2005 |
| Genome-wide identification of hypoxia-inducible factor binding sites and target genes by a probabilistic model integrating transcription-profiling data and in silico binding … A Ortiz-Barahona, D Villar, N Pescador, J Amigo, L del Peso Nucleic acids research 38 (7), 2332-2345, 2010 | 247 | 2010 |
| The von Hippel Lindau/hypoxia-inducible factor (HIF) pathway regulates the transcription of the HIF-proline hydroxylase genes in response to low oxygen L del Peso, MC Castellanos, E Temes, S Martín-Puig, Y Cuevas, G Olmos, ... Journal of Biological Chemistry 278 (49), 48690-48695, 2003 | 237 | 2003 |
| Rho proteins induce metastatic properties in vivo L Peso, R Hernández-Alcoceba, N Embade, A Carnero, P Esteve, C Paje, ... Oncogene 15 (25), 3047-3057, 1997 | 218 | 1997 |
| Hypoxia inducible factor 1-alpha (HIF-1 alpha) is induced during reperfusion after renal ischemia and is critical for proximal tubule cell survival E Conde, L Alegre, I Blanco-Sanchez, D Saenz-Morales, E Aguado-Fraile, ... PloS one 7 (3), e33258, 2012 | 195 | 2012 |
| Caenorhabditis elegans EGL-1 disrupts the interaction of CED-9 with CED-4 and promotes CED-3 activation L del Peso, VM González, G Nunez Journal of Biological Chemistry 273 (50), 33495-33500, 1998 | 162 | 1998 |
| Lack of evidence for the involvement of the phosphoinositide 3-kinase/Akt pathway in the activation of hypoxia-inducible factors by low oxygen tension M Alvarez-Tejado, A Alfranca, J Aragonés, A Vara, MO Landázuri, ... Journal of Biological Chemistry 277 (16), 13508-13517, 2002 | 159 | 2002 |
| Regulation of the forkhead transcription factor FKHR, but not the PAX3-FKHR fusion protein, by the serine/threonine kinase Akt L del Peso, VM González, R Hernández, FG Barr, G Núñez Oncogene 18 (51), 7328-7333, 1999 | 152 | 1999 |
| The Transcription Factor Encyclopedia D Yusuf, SL Butland, MI Swanson, E Bolotin, A Ticoll, WA Cheung, ... Genome Biology 13 (3), R24, 2012 | 141 | 2012 |
| Targeting tumour hypoxia to prevent cancer metastasis. From biology, biosensing and technology to drug development: the METOXIA consortium EO Pettersen, P Ebbesen, RG Gieling, KJ Williams, L Dubois, P Lambin, ... Journal of enzyme inhibition and medicinal chemistry 30 (5), 689-721, 2015 | 135 | 2015 |
| Generation of phosphorylcholine as an essential event in the activation of Raf‐1 and MAP‐kinases in growth factors‐induced mitogenic stimulation B Jiménez, L del Peso, S Montaner, P Esteve, JC Lacal Journal of cellular biochemistry 57 (1), 141-149, 1995 | 127 | 1995 |
| EFNA3 long noncoding RNAs induced by hypoxia promote metastatic dissemination L Gómez-Maldonado, M Tiana, O Roche, A Prado-Cabrero, L Jensen, ... Oncogene 34 (20), 2609-2620, 2015 | 121 | 2015 |
| Rho-regulated signals induce apoptosis in vitro and in vivo by a p53-independent, but Bcl2 dependent pathway P Esteve, N Embade, R Perona, B Jiménez, L Peso, J León, M Arends, ... Oncogene 17 (14), 1855-1869, 1998 | 118 | 1998 |
| Disruption of the CED-9· CED-4 Complex by EGL-1 Is a critical step for programmed cell death incaenorhabditis elegans L Del Peso, VM González, N Inohara, RE Ellis, G Núñez Journal of Biological Chemistry 275 (35), 27205-27211, 2000 | 115 | 2000 |
Gabriel NuñezPaul de Kruif Professor of Pathology, University of Michigan Medical SchoolCorreu electrònic verificat a umich.edu
