Simon-Pierre Gravel

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Michael PollakMcGill UniversityCorreu electrònic verificat a mcgill.ca
ivan topisirovicProfessor, McGill UniversityCorreu electrònic verificat a mcgill.ca
Daina AvizonisAcademic AssociateCorreu electrònic verificat a mcgill.ca
Masahiro MoritaAssociate Professor with Tenure (principal investigator), Dept of Mol Med and Barshop InstituteCorreu electrònic verificat a uthscsa.edu
Ola LarssonAssociate professor, Karolinska InstitutetCorreu electrònic verificat a ki.se
Sylvia AndrzejewskiMcGill University, Novo NordiskCorreu electrònic verificat a mail.mcgill.ca
Arnim Pause, M.Sc., Ph.D.Professor, Department of Biochemistry, Goodman Cencer Research Centre, McGill UniversityCorreu electrònic verificat a mcgill.ca
Valentina GandinJanelia Research CampusCorreu electrònic verificat a hhmi.org
Laura HuleaAssistant Professor, University of MontrealCorreu electrònic verificat a umontreal.ca
Tommy AlainChildren's Hospital of Eastern Ontario Research Institute and University of OttawaCorreu electrònic verificat a arc.cheo.ca
Chadi ZakariaMcGill UniversityCorreu electrònic verificat a mail.mcgill.ca
Russell G JonesVan Andel Research InstituteCorreu electrònic verificat a vai.org
Nahum SonenbergGilman Cheney Professor in BiochemistryCorreu electrònic verificat a mcgill.ca
Vincent GiguereProfessor, McGill UniversityCorreu electrònic verificat a mcgill.ca
Brandon FaubertAssistant Professor- University of ChicagoCorreu electrònic verificat a UChicago.edu
Marie CargnelloPostdoctoral fellow, McGill UniversityCorreu electrònic verificat a mail.mcgill.ca
Eric H MaMcGIll UniversityCorreu electrònic verificat a mail.mcgill.ca
Sylvain MelocheInstitute of Research in Immunology and Cancer, Université de MontréalCorreu electrònic verificat a umontreal.ca
Shawn McGuirkMcGill UniversityCorreu electrònic verificat a mail.mcgill.ca
Genevieve DebloisUniversity of Montreal, IRICCorreu electrònic verificat a mail.mcgill.ca

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Simon-Pierre Gravel

Professeur agrégé / Associate professor - Faculté de pharmacie, Université de Montréal

Correu electrònic verificat a umontreal.ca - Pàgina d'inici

Metabolism Cancer Inflammation Molecular mechanisms Drug targets


Títol Ordena per cites Ordena per any Ordena per títol	Citada per Citada per	Any
mTORC1 controls mitochondrial activity and biogenesis through 4E-BP-dependent translational regulation M Morita, SP Gravel, V Chenard, K Sikström, L Zheng, T Alain, V Gandin, ... Cell metabolism 18 (5), 698-711, 2013	870	2013
mTOR coordinates protein synthesis, mitochondrial activity and proliferation M Morita, SP Gravel, L Hulea, O Larsson, M Pollak, J St-Pierre, ... Cell cycle 14 (4), 473-480, 2015	555	2015
AMPK maintains cellular metabolic homeostasis through regulation of mitochondrial reactive oxygen species RC Rabinovitch, B Samborska, B Faubert, EH Ma, SP Gravel, ... Cell reports 21 (1), 1-9, 2017	522	2017
Metformin directly acts on mitochondria to alter cellular bioenergetics S Andrzejewski, SP Gravel, M Pollak, J St-Pierre Cancer & metabolism 2, 1-14, 2014	492	2014
nanoCAGE reveals 5′ UTR features that define specific modes of translation of functionally related MTOR-sensitive mRNAs V Gandin, L Masvidal, L Hulea, SP Gravel, M Cargnello, S McLaughlan, ... Genome research 26 (5), 636-648, 2016	239	2016
PGC-1α supports glutamine metabolism in breast cancer S McGuirk, SP Gravel, G Deblois, DJ Papadopoli, B Faubert, A Wegner, ... Cancer & metabolism 1, 1-11, 2013	183	2013
Serine Deprivation Enhances Antineoplastic Activity of Biguanides SP Gravel, L Hulea, N Toban, E Birman, MJ Blouin, M Zakikhani, Y Zhao, ... Cancer research 74 (24), 7521-7533, 2014	144	2014
ERRα mediates metabolic adaptations driving lapatinib resistance in breast cancer G Deblois, HW Smith, IS Tam, SP Gravel, M Caron, P Savage, DP Labbé, ... Nature communications 7 (1), 12156, 2016	127	2016
Involvement of the IκB kinase (IKK)-related kinases tank-binding kinase 1/IKKi and cullin-based ubiquitin ligases in IFN regulatory factor-3 degradation A Bibeau-Poirier, SP Gravel, JF Clément, S Rolland, G Rodier, ... The Journal of Immunology 177 (8), 5059-5067, 2006	119	2006
Phosphorylation of IRF-3 on Ser 339 generates a hyperactive form of IRF-3 through regulation of dimerization and CBP association JF Clément, A Bibeau-Poirier, SP Gravel, N Grandvaux, É Bonneil, ... Journal of virology 82 (8), 3984-3996, 2008	117	2008
The proinflammatory actions of angiotensin II are dependent on p65 phosphorylation by the IκB kinase complex A Douillette, A Bibeau-Poirier, SP Gravel, JF Clément, V Chénard, ... Journal of Biological Chemistry 281 (19), 13275-13284, 2006	104	2006
The PGC-1α/ERRα axis represses one-carbon metabolism and promotes sensitivity to anti-folate therapy in breast cancer E Audet-Walsh, DJ Papadopoli, SP Gravel, T Yee, G Bridon, M Caron, ... Cell reports 14 (4), 920-931, 2016	98	2016
Translational and HIF-1α-dependent metabolic reprogramming underpin metabolic plasticity and responses to kinase inhibitors and biguanides L Hulea, SP Gravel, M Morita, M Cargnello, O Uchenunu, YK Im, ... Cell metabolism 28 (6), 817-832. e8, 2018	84	2018
LKB1 deficiency in T cells promotes the development of gastrointestinal polyposis MC Poffenberger, A Metcalfe-Roach, E Aguilar, J Chen, BE Hsu, ... Science 361 (6400), 406-411, 2018	64	2018
RSK Regulates PFK-2 Activity to Promote Metabolic Rewiring in Melanoma PPR Thibault Houles, Simon-Pierre Gravel, Geneviève Lavoie, Sejeong Shin ... Cancer Research, 2018	63	2018
The complete targeted profile of the organic acid intermediates of the citric acid cycle using a single stable isotope dilution analysis, sodium borodeuteride reduction and … O Mamer, SP Gravel, L Choiniere, V Chénard, J St-Pierre, D Avizonis Metabolomics 9, 1019-1030, 2013	59	2013
Roles of an IκB kinase-related pathway in human cytomegalovirus-infected vascular smooth muscle cells: a molecular link in pathogen-induced proatherosclerotic conditions SP Gravel, MJ Servant Journal of Biological Chemistry 280 (9), 7477-7486, 2005	53	2005
Stable isotope tracer analysis in isolated mitochondria from mammalian systems SP Gravel, S Andrzejewski, D Avizonis, J St-Pierre Metabolites 4 (2), 166-183, 2014	41	2014
Alternative polyadenylation confers Pten mRNAs stability and resistance to microRNAs C Thivierge, HW Tseng, VK Mayya, C Lussier, SP Gravel, TF Duchaine Nucleic acids research 46 (19), 10340-10352, 2018	34	2018
Deciphering the dichotomous effects of PGC-1α on tumorigenesis and metastasis SP Gravel Frontiers in Oncology 8, 75, 2018	31	2018

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