| Nutrients suppress phosphatidylinositol 3-kinase/Akt signaling via raptor-dependent mTOR-mediated insulin receptor substrate 1 phosphorylation A Tzatsos, KV Kandror Molecular and cellular biology 26 (1), 63-76, 2006 | 518 | 2006 |
| STAT3 Plays a Critical Role in KRAS-Induced Pancreatic Tumorigenesis RB Corcoran, G Contino, V Deshpande, A Tzatsos, C Conrad, CH Benes, ... Cancer research 71 (14), 5020-5029, 2011 | 493 | 2011 |
| The Lkb1 metabolic sensor maintains haematopoietic stem cell survival S Gurumurthy, SZ Xie, B Alagesan, J Kim, RZ Yusuf, B Saez, A Tzatsos, ... Nature 468 (7324), 659-663, 2010 | 448 | 2010 |
| Loss of KDM6A activates super-enhancers to induce gender-specific squamous-like pancreatic cancer and confers sensitivity to BET inhibitors J Andricovich, S Perkail, Y Kai, N Casasanta, W Peng, A Tzatsos Cancer cell 33 (3), 512-526. e8, 2018 | 284 | 2018 |
| KDM2B promotes pancreatic cancer via Polycomb-dependent and-independent transcriptional programs A Tzatsos, P Paskaleva, F Ferrari, V Deshpande, S Stoykova, G Contino, ... The Journal of clinical investigation 123 (2), 727-739, 2013 | 191 | 2013 |
| Hippo signaling regulates differentiation and maintenance in the exocrine pancreas T Gao, D Zhou, C Yang, T Singh, A Penzo–Méndez, R Maddipati, ... Gastroenterology 144 (7), 1543-1553. e1, 2013 | 180 | 2013 |
| Energy depletion inhibits phosphatidylinositol 3-kinase/Akt signaling and induces apoptosis via AMP-activated protein kinase-dependent phosphorylation of IRS-1 at Ser-794 A Tzatsos, PN Tsichlis Journal of Biological Chemistry 282 (25), 18069-18082, 2007 | 174 | 2007 |
| Ndy1/KDM2B immortalizes mouse embryonic fibroblasts by repressing the Ink4a/Arf locus A Tzatsos, R Pfau, SC Kampranis, PN Tsichlis Proceedings of the National Academy of Sciences 106 (8), 2641-2646, 2009 | 154 | 2009 |
| Members of a family of JmjC domain-containing oncoproteins immortalize embryonic fibroblasts via a JmjC domain-dependent process R Pfau, A Tzatsos, SC Kampranis, OB Serebrennikova, SE Bear, ... Proceedings of the National Academy of Sciences 105 (6), 1907-1912, 2008 | 148 | 2008 |
| miR-137 mediates the functional link between c-Myc and EZH2 that regulates cisplatin resistance in ovarian cancer J Sun, X Cai, MMH Yung, W Zhou, J Li, Y Zhang, Z Li, SS Liu, ... Oncogene 38 (4), 564-580, 2019 | 131 | 2019 |
| Lysine-specific demethylase 2B (KDM2B)-let-7-enhancer of zester homolog 2 (EZH2) pathway regulates cell cycle progression and senescence in primary cells A Tzatsos, P Paskaleva, S Lymperi, G Contino, S Stoykova, Z Chen, ... Journal of Biological Chemistry 286 (38), 33061-33069, 2011 | 127 | 2011 |
| Nutrient-sensing mTOR-mediated pathway regulates leptin production in isolated rat adipocytes C Roh, J Han, A Tzatsos, KV Kandror American Journal of Physiology-Endocrinology and Metabolism 284 (2), E322-E330, 2003 | 127 | 2003 |
| Histone demethylase KDM2B regulates lineage commitment in normal and malignant hematopoiesis J Andricovich, Y Kai, W Peng, A Foudi, A Tzatsos The Journal of clinical investigation 126 (3), 905-920, 2016 | 95 | 2016 |
| Targeting IL13Ralpha2 activates STAT6-TP63 pathway to suppress breast cancer lung metastasis P Papageorgis, S Ozturk, AW Lambert, CM Neophytou, A Tzatsos, ... Breast Cancer Research 17, 1-15, 2015 | 89 | 2015 |
| Raptor binds the SAIN (Shc and IRS-1 NPXY binding) domain of insulin receptor substrate-1 (IRS-1) and regulates the phosphorylation of IRS-1 at Ser-636/639 by mTOR A Tzatsos Journal of Biological Chemistry 284 (34), 22525-22534, 2009 | 84 | 2009 |
| DUOXA1-mediated ROS production promotes cisplatin resistance by activating ATR-Chk1 pathway in ovarian cancer Y Meng, CW Chen, MMH Yung, W Sun, J Sun, Z Li, J Li, Z Li, W Zhou, ... Cancer letters 428, 104-116, 2018 | 68 | 2018 |
| Predicting CTCF-mediated chromatin interactions by integrating genomic and epigenomic features Y Kai, J Andricovich, Z Zeng, J Zhu, A Tzatsos, W Peng Nature communications 9 (1), 4221, 2018 | 56 | 2018 |
| Vitamin D deficiency promotes liver tumor growth in transforming growth factor-β/Smad3-deficient mice through Wnt and toll-like receptor 7 pathway modulation J Chen, LH Katz, NM Muñoz, S Gu, J Shin, WS Jogunoori, MH Lee, ... Scientific reports 6 (1), 30217, 2016 | 52 | 2016 |
| Ink4a/Arf regulation by let-7b and Hmga2: a genetic pathway governing stem cell aging A Tzatsos, N Bardeesy Cell stem cell 3 (5), 469-470, 2008 | 43 | 2008 |
| Loss of the transforming growth factor‐β effector β2‐Spectrin promotes genomic instability J Chen, V Shukla, P Farci, J Andricovich, W Jogunoori, LN Kwong, ... Hepatology 65 (2), 678-693, 2017 | 39 | 2017 |