| Induction of LIFR confers a dormancy phenotype in breast cancer cells disseminated to the bone marrow RW Johnson, EC Finger, MM Olcina, M Vilalta, T Aguilera, Y Miao, ... Nature cell biology 18 (10), 1078-1089, 2016 | 255 | 2016 |
| TGF-β promotion of Gli2-induced expression of parathyroid hormone-related protein, an important osteolytic factor in bone metastasis, is independent of canonical Hedgehog signaling RW Johnson, MP Nguyen, SS Padalecki, BG Grubbs, AR Merkel, ... Cancer research 71 (3), 822-831, 2011 | 229 | 2011 |
| Myeloid-derived suppressor cells expand during breast cancer progression and promote tumor-induced bone destruction S Danilin, AR Merkel, JR Johnson, RW Johnson, JR Edwards, JA Sterling Oncoimmunology 1 (9), 1484-1494, 2012 | 151 | 2012 |
| Models of bone metastasis JP Campbell, AR Merkel, SK Masood-Campbell, F Elefteriou, JA Sterling Journal of visualized experiments: JoVE, 4260, 2012 | 149 | 2012 |
| Matrix rigidity induces osteolytic gene expression of metastatic breast cancer cells NS Ruppender, AR Merkel, TJ Martin, GR Mundy, JA Sterling, ... PloS one 5 (11), e15451, 2010 | 101 | 2010 |
| ALCAM/CD166 Is a TGF-β–responsive marker and functional regulator of prostate cancer metastasis to bone AG Hansen, SA Arnold, M Jiang, TD Palmer, T Ketova, A Merkel, ... Cancer research 74 (5), 1404-1415, 2014 | 94 | 2014 |
| Matrix rigidity regulates the transition of tumor cells to a bone-destructive phenotype through integrin β3 and TGF-β receptor type II JM Page, AR Merkel, NS Ruppender, R Guo, UC Dadwal, SA Cannonier, ... Biomaterials 64, 33-44, 2015 | 90 | 2015 |
| Substrate modulus of 3D-printed scaffolds regulates the regenerative response in subcutaneous implants through the macrophage phenotype and Wnt signaling R Guo, AR Merkel, JA Sterling, JM Davidson, SA Guelcher Biomaterials 73, 85-95, 2015 | 82 | 2015 |
| Changes in the fracture resistance of bone with the progression of type 2 diabetes in the ZDSD rat A Creecy, S Uppuganti, AR Merkel, D O’Neal, AJ Makowski, M Granke, ... Calcified tissue international 99, 289-301, 2016 | 74 | 2016 |
| Skeletal colonization by breast cancer cells is stimulated by an osteoblast and β2AR‐dependent neo‐angiogenic switch PL Mulcrone, JP Campbell, L Clément‐Demange, AL Anbinder, ... Journal of Bone and Mineral Research 32 (7), 1442-1454, 2017 | 73 | 2017 |
| Tuning ligand density to optimize pharmacokinetics of targeted nanoparticles for dual protection against tumor-induced bone destruction J Vanderburgh, JL Hill, MK Gupta, KA Kwakwa, SK Wang, K Moyer, ... ACS nano 14 (1), 311-327, 2020 | 60 | 2020 |
| Wnt signaling induces gene expression of factors associated with bone destruction in lung and breast cancer RW Johnson, AR Merkel, JM Page, NS Ruppender, SA Guelcher, ... Clinical & experimental metastasis 31, 945-959, 2014 | 60 | 2014 |
| Prostate cancer metastases alter bone mineral and matrix composition independent of effects on bone architecture in mice—a quantitative study using microCT and Raman spectroscopy X Bi, JA Sterling, AR Merkel, DS Perrien, JS Nyman, ... Bone 56 (2), 454-460, 2013 | 56 | 2013 |
| Platelet-derived β2M regulates monocyte inflammatory responses ZT Hilt, DN Pariser, SK Ture, A Mohan, P Quijada, AA Asante, ... JCI insight 4 (5), 2019 | 49 | 2019 |
| Fabrication of 3D scaffolds with precisely controlled substrate modulus and pore size by templated-fused deposition modeling to direct osteogenic differentiation R Guo, S Lu, JM Page, AR Merkel, S Basu, JA Sterling, SA Guelcher Advanced healthcare materials 4 (12), 1826, 2015 | 47 | 2015 |
| Combined treatment with a transforming growth factor beta inhibitor (1D11) and bortezomib improves bone architecture in a mouse model of myeloma-induced bone disease JS Nyman, AR Merkel, S Uppuganti, B Nayak, B Rowland, AJ Makowski, ... Bone 91, 81-91, 2016 | 45 | 2016 |
| Systemic delivery of a Gli inhibitor via polymeric nanocarriers inhibits tumor-induced bone disease JP Vanderburgh, KA Kwakwa, TA Werfel, AR Merkel, MK Gupta, ... Journal of Controlled Release 311, 257-272, 2019 | 37 | 2019 |
| TRIzol and Alu qPCR-based quantification of metastatic seeding within the skeleton J Preston Campbell, P Mulcrone, SK Masood, M Karolak, A Merkel, ... Scientific Reports 5 (1), 12635, 2015 | 34 | 2015 |
| Predicting mouse vertebra strength with micro-computed tomography-derived finite element analysis JS Nyman, S Uppuganti, AJ Makowski, BJ Rowland, AR Merkel, ... BoneKEy reports 4, 2015 | 29 | 2015 |
| Settable polymer/ceramic composite bone grafts stabilize weight-bearing tibial plateau slot defects and integrate with host bone in an ovine model S Lu, MAP McGough, SM Shiels, KJ Zienkiewicz, AR Merkel, ... Biomaterials 179, 29-45, 2018 | 26 | 2018 |