| Primary structure and functional expression of the human cardiac tetrodotoxin-insensitive voltage-dependent sodium channel. ME Gellens, AL George Jr, LQ Chen, M Chahine, R Horn, RL Barchi, ... Proceedings of the National Academy of Sciences 89 (2), 554-558, 1992 | 786 | 1992 |
| Sodium channel mutations in paramyotonia congenita uncouple inactivation from activation M Chahine, AL George Jr, M Zhou, S Ji, W Sun, RL Barchi, R Horn Neuron 12 (2), 281-294, 1994 | 380 | 1994 |
| SCN5A Polymorphism Restores Trafficking of a Brugada Syndrome Mutation on a Separate Gene S Poelzing, C Forleo, M Samodell, L Dudash, S Sorrentino, M Anaclerio, ... Circulation 114 (5), 368-376, 2006 | 245 | 2006 |
| Electrophysiological characterization of SCN5A mutations causing long QT (E1784K) and Brugada (R1512W and R1432G) syndromes I Deschênes, G Baroudi, M Berthet, I Barde, T Chalvidan, I Denjoy, ... Cardiovascular Research 46 (1), 55-65, 2000 | 224 | 2000 |
| Novel Mechanism for Brugada Syndrome: Defective Surface Localization of an SCN5A Mutant (R1432G) G Baroudi, V Pouliot, I Denjoy, P Guicheney, A Shrier, M Chahine Circulation Research 88 (12), e78-e83, 2001 | 185 | 2001 |
| Functional expression and properties of the human skeletal muscle sodium channel M Chahine, PB Bennett, AL George, R Horn Pflügers Archiv 427, 136-142, 1994 | 151 | 1994 |
| Modulation of Nav1.7 and Nav1.8 Peripheral Nerve Sodium Channels by Protein Kinase A and Protein Kinase C K Vijayaragavan, M Boutjdir, M Chahine Journal of neurophysiology 91 (4), 1556-1569, 2004 | 149 | 2004 |
| Differential modulation of Nav1.7 and Nav1.8 peripheral nerve sodium channels by the local anesthetic lidocaine P Chevrier, K Vijayaragavan, M Chahine British journal of pharmacology 142 (3), 576-584, 2004 | 146 | 2004 |
| Thioridazine lengthens repolarization of cardiac ventricular myocytes by blocking the delayed rectifier potassium current B Drolet, F Vincent, J Rail, M Chahine, D Deschênes, S Nadeau, ... The Journal of pharmacology and experimental therapeutics 288 (3), 1261-1268, 1999 | 144 | 1999 |
| Gain-of-function mutation of Nav1. 5 in atrial fibrillation enhances cellular excitability and lowers the threshold for action potential firing Q Li, H Huang, G Liu, K Lam, J Rutberg, MS Green, DH Birnie, R Lemery, ... Biochemical and biophysical research communications 380 (1), 132-137, 2009 | 143 | 2009 |
| Homozygous SCN5A Mutation in Long-QT Syndrome With Functional Two-to-One Atrioventricular Block JM Lupoglazoff, T Cheav, G Baroudi, M Berthet, I Denjoy, B Cauchemez, ... Circulation Research 89 (2), e16-e21, 2001 | 142 | 2001 |
| Enzyme domain affects the movement of the voltage sensor in ascidian and zebrafish voltage-sensing phosphatases MI Hossain, H Iwasaki, Y Okochi, M Chahine, S Higashijima, K Nagayama, ... Journal of Biological Chemistry 283 (26), 18248-18259, 2008 | 140 | 2008 |
| A Newly Characterized SCN5A Mutation Underlying Brugada Syndrome Unmasked by Hyperthermia NS MOK, SG Priori, C Napolitano, NYIN CHAN, M Chahine, G Baroudi Journal of cardiovascular electrophysiology 14 (4), 407-411, 2003 | 140 | 2003 |
| Expression and Intracellular Localization of an SCN5A Double Mutant R1232W/T1620M Implicated in Brugada Syndrome G Baroudi, S Acharfi, C Larouche, M Chahine Circulation research 90 (1), e11-e16, 2002 | 140 | 2002 |
| Interleukin-6 inhibition of hERG underlies risk for acquired long QT in cardiac and systemic inflammation AS Aromolaran, U Srivastava, A Alí, M Chahine, D Lazaro, N El-Sherif, ... PLoS One 13 (12), e0208321, 2018 | 136 | 2018 |
| Genetic associations of protein-coding variants in human disease BB Sun, MI Kurki, CN Foley, A Mechakra, CY Chen, E Marshall, JB Wilk, ... Nature 603 (7899), 95-102, 2022 | 119 | 2022 |
| A proton leak current through the cardiac sodium channel is linked to mixed arrhythmia and the dilated cardiomyopathy phenotype P Gosselin-Badaroudine, DI Keller, H Huang, V Pouliot, A Chatelier, ... PloS one 7 (5), e38331, 2012 | 118 | 2012 |
| Gating properties of Nav1. 7 and Nav1. 8 peripheral nerve sodium channels K Vijayaragavan, ME O'Leary, M Chahine Journal of Neuroscience 21 (20), 7909-7918, 2001 | 114 | 2001 |
| Voltage-gated sodium channels in neurological disorders M Chahine, A Chatelier, O Babich, JJ Krupp CNS & Neurological Disorders-Drug Targets-CNS & Neurological Disorders) 7 (2 …, 2008 | 108 | 2008 |
| Biophysical phenotypes of SCN5A mutations causing long QT and Brugada syndromes G Baroudi, M Chahine FEBS letters 487 (2), 224-228, 2000 | 107 | 2000 |
Mohamed BoutjdirVA New York Harbor Healthcare System, SUNY Downstate Medical Center and NYU School of MedicineCorreu electrònic verificat a nyumc.org