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Michael J McCarthy
Michael J McCarthy
Arvinas
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Discovery of high-affinity noncovalent allosteric KRAS inhibitors that disrupt effector binding
MJ McCarthy, CV Pagba, P Prakash, AK Naji, D van der Hoeven, H Liang, ...
ACS omega 4 (2), 2921-2930, 2019
842019
Computational allosteric ligand binding site identification on Ras proteins
M McCarthy, P Prakash, AA Gorfe
Acta biochimica et biophysica Sinica 48 (1), 3-10, 2016
312016
Exon Organization and Novel Alternative Splicing of Ank3 in Mouse Heart
G Yamankurt, HC Wu, M McCarthy, SR Cunha
PLoS One 10 (5), e0128177, 2015
142015
Reverse molecular docking and deep-learning to make predictions of receptor activity for neurotoxicology
JMG M.J.McCarthy, Y.Chushak
Computational Toxicology 24 (100238), 2022
42022
Identification and characterization of self-association domains on small ankyrin 1 isoforms
J Subramaniam, P Yang, MJ McCarthy, SR Cunha
Journal of molecular and cellular cardiology 139, 225-237, 2020
42020
Methods and compositions for kras inhibitors
AG Abebe, MJ McCarthy, CV Pagbal, PP Srivastava
US Patent App. 17/469,457, 2021
12021
Methods and compositions for KRAS inhibitors
AG Abebe, MJ McCarthy, CV Pagba, PP Srivastava
US Patent 11,141,418, 2021
12021
Novel psychedelic compositions, delivery systems and therapeutic uses thereof
JC Gustin, MJ Mccarthy
US Patent App. 18/029,543, 2023
2023
Methods and compositions for KRAS inhibitors
PPS AG Abebe, MJ McCarthy, CV Pagba
2021
Structurally-Diverse Non-Covalent Allosteric KRAS Inhibitors Structurally Diverse Non-Covalent Allosteric KRAS Inhibitors
C Pagba, AK Gupta, M McCarthy, Y Zhou, AA Gorfe
Biophysical Journal 118 (3), 324a, 2020
2020
Discovery of allosteric non-covalent KRAS inhibitors that bind with sub-micromolar affinity and disrupt effector binding
MJ McCarthy, CV Pagba, P Prakash, A Naji, D van der Hoeven, H Liang, ...
bioRxiv, 440487, 2018
2018
Structure Based Drug Design Of High Affinity Kras Inhibitors
M McCarthy
2018
Studying Aggregate Formation By Amyotrophic Lateral Sclerosis-Associated Mutant Sod1 Protein In Drosophila Model
M McCarthy
2013
En aquests moments el sistema no pot dur a terme l'operació. Torneu-ho a provar més tard.
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