| Somatic mutations at EZH2 Y641 act dominantly through a mechanism of selectively altered PRC2 catalytic activity, to increase H3K27 trimethylation DB Yap, J Chu, T Berg, M Schapira, SWG Cheng, A Moradian, RD Morin, ... Blood, The Journal of the American Society of Hematology 117 (8), 2451-2459, 2011 | 737 | 2011 |
| Sorafenib Maintenance After Allogeneic Hematopoietic Stem Cell Transplantation for Acute Myeloid Leukemia With FLT3–Internal Tandem Duplication Mutation … A Burchert, G Bug, LV Fritz, J Finke, M Stelljes, C Röllig, E Wollmer, ... Journal of Clinical Oncology 38 (26), 2993-3002, 2020 | 491 | 2020 |
| Comprehensive microRNA expression profiling of the hematopoietic hierarchy OI Petriv, F Kuchenbauer, AD Delaney, V Lecault, A White, D Kent, ... Proceedings of the National Academy of Sciences 107 (35), 15443-15448, 2010 | 206 | 2010 |
| Comprehensive analysis of mammalian miRNA* species and their role in myeloid cells F Kuchenbauer, SM Mah, M Heuser, A McPherson, J Rüschmann, ... Blood, The Journal of the American Society of Hematology 118 (12), 3350-3358, 2011 | 133 | 2011 |
| Hoxa9 and Meis1 cooperatively induce addiction to Syk signaling by suppressing miR-146a in acute myeloid leukemia S Mohr, C Doebele, F Comoglio, T Berg, J Beck, H Bohnenberger, ... Cancer cell 31 (4), 549-562. e11, 2017 | 129 | 2017 |
| Sorafenib as maintenance therapy post allogeneic stem cell transplantation for FLT3-ITD positive AML: results from the randomized, double-blind, placebo-controlled multicentre … A Burchert, G Bug, J Finke, M Stelljes, C Rollig, R Wäsch, M Bornhäuser, ... Blood 132, 661, 2018 | 124 | 2018 |
| Cell of origin in AML: susceptibility to MN1-induced transformation is regulated by the MEIS1/AbdB-like HOX protein complex M Heuser, H Yun, T Berg, E Yung, B Argiropoulos, F Kuchenbauer, ... Cancer cell 20 (1), 39-52, 2011 | 118 | 2011 |
| A transgenic mouse model demonstrating the oncogenic role of mutations in the polycomb-group gene EZH2 in lymphomagenesis T Berg, S Thoene, D Yap, T Wee, N Schoeler, P Rosten, E Lim, M Bilenky, ... Blood, The Journal of the American Society of Hematology 123 (25), 3914-3924, 2014 | 107 | 2014 |
| Phase I/II study of the deacetylase inhibitor panobinostat after allogeneic stem cell transplantation in patients with high-risk MDS or AML (PANOBEST trial) G Bug, A Burchert, EM Wagner, N Kröger, T Berg, S Güller, SK Metzelder, ... Leukemia 31 (11), 2523-2525, 2017 | 101 | 2017 |
| NOX4-driven ROS formation mediates PTP inactivation and cell transformation in FLT3ITD-positive AML cells AK Jayavelu, JP Müller, R Bauer, SA Böhmer, J Lässig, S Cerny-Reiterer, ... Leukemia 30 (2), 473-483, 2016 | 82 | 2016 |
| Ibrutinib for bridging to allogeneic hematopoietic cell transplantation in patients with chronic lymphocytic leukemia or mantle cell lymphoma: a study by the EBMT Chronic … P Dreger, M Michallet, P Bosman, S Dietrich, M Sobh, A Boumendil, ... Bone marrow transplantation 54 (1), 44-52, 2019 | 73 | 2019 |
| β2 integrin–derived signals induce cell survival and proliferation of AML blasts by activating a Syk/STAT signaling axis T Oellerich, MF Oellerich, M Engelke, S Münch, S Mohr, M Nimz, ... Blood, The Journal of the American Society of Hematology 121 (19), 3889-3899, 2013 | 70 | 2013 |
| LSD1 inhibition by tranylcypromine derivatives interferes with GFI1-mediated repression of PU. 1 target genes and induces differentiation in AML J Barth, K Abou-El-Ardat, D Dalic, N Kurrle, AM Maier, S Mohr, J Schütte, ... Leukemia 33 (6), 1411-1426, 2019 | 67 | 2019 |
| Reversal of p15/INK4b hypermethylation in AML1/ETO-positive and-negative myeloid leukemia cell lines T Berg, Y Guo, M Abdelkarim, M Fliegauf, M Lübbert Leukemia research 31 (4), 497-506, 2007 | 56 | 2007 |
| The HDAC class I-specific inhibitor entinostat (MS-275) effectively relieves epigenetic silencing of the LAT2 gene mediated by AML1/ETO J Duque-Afonso, A Yalcin, T Berg, M Abdelkarim, O Heidenreich, ... Oncogene 30 (27), 3062-3072, 2011 | 55 | 2011 |
| Leukemia targeting ligands isolated from phage display peptide libraries S Jäger, A Jahnke, T Wilmes, S Adebahr, FN Vögtle, E Delima-Hahn, ... Leukemia 21 (3), 411-420, 2007 | 51 | 2007 |
| Functional role of BAALC in leukemogenesis M Heuser, T Berg, F Kuchenbauer, CK Lai, G Park, S Fung, G Lin, ... Leukemia 26 (3), 532-536, 2012 | 49 | 2012 |
| Williams–Beuren syndrome critical region-5/non-T-cell activation linker: a novel target gene of AML1/ETO M Fliegauf, M Stock, T Berg, M Lübbert Oncogene 23 (56), 9070-9081, 2004 | 42 | 2004 |
| MicroRNA-223 dose levels fine tune proliferation and differentiation in human cord blood progenitors and acute myeloid leukemia B Gentner, N Pochert, A Rouhi, F Boccalatte, T Plati, T Berg, SM Sun, ... Experimental hematology 43 (10), 858-868. e7, 2015 | 41 | 2015 |
| Structure-activity studies on N-substituted tranylcypromine derivatives lead to selective inhibitors of lysine specific demethylase 1 (LSD1) and potent inducers of leukemic … J Schulz-Fincke, M Hau, J Barth, D Robaa, D Willmann, A Kürner, J Haas, ... European Journal of Medicinal Chemistry 144, 52-67, 2018 | 40 | 2018 |
Samuel AparicioUBC, BC Cancer Agency, VancouverCorreu electrònic verificat a bccrc.ca