| p53 dynamics control cell fate JE Purvis, KW Karhohs, C Mock, E Batchelor, A Loewer, G Lahav Science 336 (6087), 1440-1444, 2012 | 929 | 2012 |
| Encoding and decoding cellular information through signaling dynamics JE Purvis, G Lahav Cell 152 (5), 945-956, 2013 | 869 | 2013 |
| Enhanced Trehalose Production Improves Growth of Escherichia coli under Osmotic Stress JE Purvis, LP Yomano, LO Ingram Applied and environmental microbiology 71 (7), 3761-3769, 2005 | 231 | 2005 |
| Orchestration of DNA damage checkpoint dynamics across the human cell cycle HX Chao, CE Poovey, AA Privette, GD Grant, HY Chao, JG Cook, ... Cell systems 5 (5), 445-459. e5, 2017 | 176 | 2017 |
| A proximal-to-distal survey of healthy adult human small intestine and colon epithelium by single-cell transcriptomics J Burclaff, RJ Bliton, KA Breau, MT Ok, I Gomez-Martinez, JS Ranek, ... Cellular and molecular gastroenterology and hepatology 13 (5), 1554-1589, 2022 | 168 | 2022 |
| Genetic determinants of cellular addiction to DNA polymerase theta W Feng, DA Simpson, J Carvajal-Garcia, BA Price, RJ Kumar, LE Mose, ... Nature communications 10 (1), 4286, 2019 | 166 | 2019 |
| Gene Array‐Based Identification of Changes That Contribute to Ethanol Tolerance in Ethanologenic Escherichia coli: Comparison of KO11 (Parent) to LY01 … R Gonzalez, H Tao, JE Purvis, SW York, KT Shanmugam, LO Ingram Biotechnology progress 19 (2), 612-623, 2003 | 157 | 2003 |
| A small-molecule oxocarbazate inhibitor of human cathepsin L blocks severe acute respiratory syndrome and ebola pseudotype virus infection into human embryonic kidney 293T cells PP Shah, T Wang, RL Kaletsky, MC Myers, JE Purvis, H Jing, DM Huryn, ... Molecular pharmacology 78 (2), 319-324, 2010 | 137 | 2010 |
| A molecular signaling model of platelet phosphoinositide and calcium regulation during homeostasis and P2Y1 activation JE Purvis, MS Chatterjee, LF Brass, SL Diamond Blood, The Journal of the American Society of Hematology 112 (10), 4069-4079, 2008 | 126 | 2008 |
| Pairwise agonist scanning predicts cellular signaling responses to combinatorial stimuli MS Chatterjee, JE Purvis, LF Brass, SL Diamond Nature biotechnology 28 (7), 727-732, 2010 | 122 | 2010 |
| Accurate delineation of cell cycle phase transitions in living cells with PIP-FUCCI GD Grant, KM Kedziora, JC Limas, JG Cook, JE Purvis Cell Cycle 17 (21-22), 2496-2516, 2018 | 112 | 2018 |
| p53 pulses lead to distinct patterns of gene expression albeit similar DNA-binding dynamics A Hafner, J Stewart-Ornstein, JE Purvis, WC Forrester, ML Bulyk, G Lahav Nature structural & molecular biology 24 (10), 840-847, 2017 | 111 | 2017 |
| Rapid DNA replication origin licensing protects stem cell pluripotency JP Matson, R Dumitru, P Coryell, RM Baxley, W Chen, K Twaroski, ... Elife 6, e30473, 2017 | 108 | 2017 |
| Evidence that the human cell cycle is a series of uncoupled, memoryless phases HX Chao, RI Fakhreddin, HK Shimerov, KM Kedziora, RJ Kumar, J Perez, ... Molecular systems biology 15 (3), e8604, 2019 | 102 | 2019 |
| Sequential replication-coupled destruction at G1/S ensures genome stability KE Coleman, GD Grant, RA Haggerty, K Brantley, E Shibata, ... Genes & development 29 (16), 1734-1746, 2015 | 65 | 2015 |
| The structure of the human cell cycle W Stallaert, KM Kedziora, CD Taylor, TM Zikry, JS Ranek, HK Sobon, ... Cell systems 13 (3), 230-240. e3, 2022 | 64 | 2022 |
| Kinetic characterization and molecular docking of a novel, potent, and selective slow-binding inhibitor of human cathepsin L PP Shah, MC Myers, MP Beavers, JE Purvis, H Jing, HJ Grieser, ... Molecular pharmacology 74 (1), 34-41, 2008 | 54 | 2008 |
| An integrative transcriptomics approach identifies miR-503 as a candidate master regulator of the estrogen response in MCF-7 breast cancer cells J Baran-Gale, JE Purvis, P Sethupathy Rna 22 (10), 1592-1603, 2016 | 53 | 2016 |
| MRE11 liberates cGAS from nucleosome sequestration during tumorigenesis MG Cho, RJ Kumar, CC Lin, JA Boyer, JA Shahir, K Fagan-Solis, ... Nature 625 (7995), 585-592, 2024 | 49 | 2024 |
| A multiscale computational approach to dissect early events in the Erb family receptor mediated activation, differential signaling, and relevance to oncogenic transformations Y Liu, J Purvis, A Shih, J Weinstein, N Agrawal, R Radhakrishnan Annals of biomedical engineering 35, 1012-1025, 2007 | 45 | 2007 |
