The immune landscape of cancer V Thorsson, DL Gibbs, SD Brown, D Wolf, DS Bortone, THO Yang, ... Immunity 51 (2), 411-412, 2019 | 5000 | 2019 |
Integrated genomic characterization of pancreatic ductal adenocarcinoma BJ Raphael, RH Hruban, AJ Aguirre, RA Moffitt, JJ Yeh, C Stewart, ... Cancer cell 32 (2), 185-203. e13, 2017 | 1746 | 2017 |
Inactivation of the DNA Repair Gene O6-Methylguanine-DNA Methyltransferase by Promoter Hypermethylation is a Common Event in Primary Human Neoplasia M Esteller, SR Hamilton, PC Burger, SB Baylin, JG Herman Cancer research 59 (4), 793-797, 1999 | 1628 | 1999 |
DNMT1 and DNMT3b cooperate to silence genes in human cancer cells I Rhee, KE Bachman, BH Park, KW Jair, RWC Yen, KE Schuebel, H Cui, ... Nature 416 (6880), 552-556, 2002 | 1594 | 2002 |
DNA methylation and gene silencing in cancer SB Baylin Nature clinical practice Oncology 2 (Suppl 1), S4-S11, 2005 | 1591 | 2005 |
Promoter hypermethylation and BRCA1 inactivation in sporadic breast and ovarian tumors M Esteller, JM Silva, G Dominguez, F Bonilla, X Matias-Guiu, E Lerma, ... JNCI: Journal of the National Cancer Institute 92 (7), 564-569, 2000 | 1553 | 2000 |
Methylation of the oestrogen receptor CpG island links ageing and neoplasia in human colon JPJ Issa, YL Ottaviano, P Celano, SR Hamilton, NE Davidson, SB Baylin Nature genetics 7 (4), 536-540, 1994 | 1469 | 1994 |
Hedgehog signalling within airway epithelial progenitors and in small-cell lung cancer DN Watkins, DM Berman, SG Burkholder, B Wang, PA Beachy, SB Baylin Nature 422 (6929), 313-317, 2003 | 1436 | 2003 |
DNMT1 binds HDAC2 and a new co-repressor, DMAP1, to form a complex at replication foci MR Rountree, KE Bachman, SB Baylin Nature genetics 25 (3), 269-277, 2000 | 1314 | 2000 |
Epigenetic inactivation of SFRP genes allows constitutive WNT signaling in colorectal cancer H Suzuki, DN Watkins, KW Jair, KE Schuebel, SD Markowitz, ... Nature genetics 36 (4), 417-422, 2004 | 1306 | 2004 |
Aberrant methylation of p16INK4a is an early event in lung cancer and a potential biomarker for early diagnosis SA Belinsky, KJ Nikula, WA Palmisano, R Michels, G Saccomanno, ... Proceedings of the National Academy of Sciences 95 (20), 11891-11896, 1998 | 1295 | 1998 |
Aberrant patterns of DNA methylation, chromatin formation and gene expression in cancer SB Baylin, M Esteller, MR Rountree, KE Bachman, K Schuebel, ... Human molecular genetics 10 (7), 687-692, 2001 | 1288 | 2001 |
Epigenetic determinants of cancer SB Baylin, PA Jones Cold Spring Harbor perspectives in biology 8 (9), a019505, 2016 | 1286 | 2016 |
A stem cell–like chromatin pattern may predispose tumor suppressor genes to DNA hypermethylation and heritable silencing JE Ohm, KM McGarvey, X Yu, L Cheng, KE Schuebel, L Cope, ... Nature genetics 39 (2), 237-242, 2007 | 1280 | 2007 |
Detection of aberrant promoter hypermethylation of tumor suppressor genes in serum DNA from non-small cell lung cancer patients M Esteller, M Sanchez-Cespedes, R Rosell, D Sidransky, SB Baylin, ... Cancer research 59 (1), 67-70, 1999 | 1276 | 1999 |
Dysfunctional KEAP1–NRF2 interaction in non-small-cell lung cancer A Singh, V Misra, RK Thimmulappa, H Lee, S Ames, MO Hoque, ... PLoS medicine 3 (10), e420, 2006 | 1243 | 2006 |
Single-quantum-dot-based DNA nanosensor CY Zhang, HC Yeh, MT Kuroki, TH Wang Nature materials 4 (11), 826-831, 2005 | 1219 | 2005 |
Targeting the cancer epigenome for therapy PA Jones, JPJ Issa, S Baylin Nature Reviews Genetics 17 (10), 630-641, 2016 | 1218 | 2016 |
Predicting lung cancer by detecting aberrant promoter methylation in sputum WA Palmisano, KK Divine, G Saccomanno, FD Gilliland, SB Baylin, ... Cancer research 60 (21), 5954-5958, 2000 | 1196 | 2000 |
Comprehensive genomic analysis identifies SOX2 as a frequently amplified gene in small-cell lung cancer CM Rudin, S Durinck, EW Stawiski, JT Poirier, Z Modrusan, DS Shames, ... Nature genetics 44 (10), 1111-1116, 2012 | 1154 | 2012 |