| CpG islands and the regulation of transcription AM Deaton, A Bird Genes & development 25 (10), 1010-1022, 2011 | 3925 | 2011 |
| CpG islands influence chromatin structure via the CpG-binding protein Cfp1 JP Thomson, PJ Skene, J Selfridge, T Clouaire, J Guy, S Webb, ARW Kerr, ... Nature 464 (7291), 1082-1086, 2010 | 787 | 2010 |
| Plasma proteomic associations with genetics and health in the UK Biobank BB Sun, J Chiou, M Traylor, C Benner, YH Hsu, TG Richardson, ... Nature 622 (7982), 329-338, 2023 | 500 | 2023 |
| A transient heterochromatic state in Xist preempts X inactivation choice without RNA stabilization BK Sun, AM Deaton, JT Lee Molecular cell 21 (5), 617-628, 2006 | 379 | 2006 |
| Cell type–specific DNA methylation at intragenic CpG islands in the immune system AM Deaton, S Webb, ARW Kerr, RS Illingworth, J Guy, R Andrews, A Bird Genome research 21 (7), 1074-1086, 2011 | 353 | 2011 |
| MNase titration reveals differences between nucleosome occupancy and chromatin accessibility J Mieczkowski, A Cook, SK Bowman, B Mueller, BH Alver, S Kundu, ... Nature communications 7 (1), 11485, 2016 | 248 | 2016 |
| A temporal threshold for formaldehyde crosslinking and fixation L Schmiedeberg, P Skene, A Deaton, A Bird PLoS One 4 (2), e4636, 2009 | 147 | 2009 |
| H3K27 modifications define segmental regulatory domains in the Drosophila bithorax complex SK Bowman, AM Deaton, H Domingues, PI Wang, RI Sadreyev, ... Elife 3, e02833, 2014 | 134 | 2014 |
| A loss-of-function variant in ALOX15 protects against nasal polyps and chronic rhinosinusitis RP Kristjansson, S Benonisdottir, OB Davidsson, A Oddsson, V Tragante, ... Nature genetics 51 (2), 267-276, 2019 | 120 | 2019 |
| Enhancer regions show high histone H3. 3 turnover that changes during differentiation AM Deaton, M Gomez-Rodriguez, J Mieczkowski, MY Tolstorukov, ... elife 5, e15316, 2016 | 106 | 2016 |
| Nucleosomal occupancy changes locally over key regulatory regions during cell differentiation and reprogramming JA West, A Cook, BH Alver, M Stadtfeld, AM Deaton, K Hochedlinger, ... Nature communications 5 (1), 4719, 2014 | 104 | 2014 |
| Phenotypes associated with genes encoding drug targets are predictive of clinical trial side effects PA Nguyen, DA Born, AM Deaton, P Nioi, LD Ward Nature communications 10 (1), 1579, 2019 | 101 | 2019 |
| Genome-wide association meta-analysis yields 20 loci associated with gallstone disease E Ferkingstad, A Oddsson, S Gretarsdottir, S Benonisdottir, G Thorleifsson, ... Nature communications 9 (1), 5101, 2018 | 99 | 2018 |
| Multiplexed Illumina sequencing libraries from picogram quantities of DNA SK Bowman, MD Simon, AM Deaton, M Tolstorukov, ML Borowsky, ... BMC genomics 14, 1-7, 2013 | 92 | 2013 |
| A dominant role for the methyl-CpG-binding protein Mbd2 in controlling Th2 induction by dendritic cells PC Cook, H Owen, AM Deaton, JG Borger, SL Brown, T Clouaire, ... Nature communications 6 (1), 6920, 2015 | 87 | 2015 |
| Using human genetics to improve safety assessment of therapeutics KJ Carss, AM Deaton, A Del Rio-Espinola, D Diogo, M Fielden, ... Nature Reviews Drug Discovery 22 (2), 145-162, 2023 | 55 | 2023 |
| Nonclinical cardiovascular safety evaluation of romosozumab, an inhibitor of sclerostin for the treatment of osteoporosis in postmenopausal women at high risk of fracture JR Turk, AM Deaton, J Yin, M Stolina, M Felx, G Boyd, JG Bienvenu, ... Regulatory Toxicology and Pharmacology 115, 104697, 2020 | 44 | 2020 |
| GWAS of serum ALT and AST reveals an association of SLC30A10 Thr95Ile with hypermanganesemia symptoms LD Ward, HC Tu, CB Quenneville, S Tsour, AO Flynn-Carroll, MM Parker, ... Nature Communications 12 (1), 4571, 2021 | 40 | 2021 |
| Gene-level analysis of rare variants in 379,066 whole exome sequences identifies an association of GIGYF1 loss of function with type 2 diabetes AM Deaton, MM Parker, LD Ward, AO Flynn-Carroll, L BonDurant, ... Scientific reports 11 (1), 21565, 2021 | 38 | 2021 |
| Sequence variants associating with urinary biomarkers S Benonisdottir, RP Kristjansson, A Oddsson, V Steinthorsdottir, ... Human molecular genetics 28 (7), 1199-1211, 2019 | 35 | 2019 |
Adrian BirdProfessor of Genetics, University of EdinburghCorreu electrònic verificat a ed.ac.uk