| d-Serine is an endogenous ligand for the glycine site of the N-methyl-d-aspartate receptor JP Mothet, AT Parent, H Wolosker, RO Brady Jr, DJ Linden, CD Ferris, ... Proceedings of the National Academy of Sciences 97 (9), 4926-4931, 2000 | 1409 | 2000 |
| Spatial segregation of γ-secretase and substrates in DistinctMembraneDomains KS Vetrivel, H Cheng, SH Kim, Y Chen, NY Barnes, AT Parent, SS Sisodia, ... Journal of Biological Chemistry 280 (27), 25892-25900, 2005 | 286 | 2005 |
| Facilitation of acetylcholine release and cognitive performance by an M (2)-muscarinic receptor antagonist in aged memory-impaired R Quirion, A Wilson, W Rowe, I Aubert, J Richard, H Doods, A Parent, ... Journal of Neuroscience 15 (2), 1455-1462, 1995 | 258 | 1995 |
| Impaired cerebellar long-term potentiation in type I adenylyl cyclase mutant mice DR Storm, C Hansel, B Hacker, A Parent, DJ Linden Neuron 20 (6), 1199-1210, 1998 | 181 | 1998 |
| Noxious thermal and chemical stimulation induce increases in 3H-phorbol 12, 13-dibutyrate binding in spinal cord dorsal horn as well as persistent pain and hyperalgesia, which … K Yashpal, GM Pitcher, A Parent, R Quirion, TJ Coderre Journal of Neuroscience 15 (5), 3263-3272, 1995 | 163 | 1995 |
| Early environmental regulation of hippocampal glucocorticoid receptor gene expression: characterization of intracellular mediators and potential genomic target sites ICG Weaver, P La Plante, S Weaver, A Parent, S Sharma, J Diorio, ... Molecular and cellular endocrinology 185 (1-2), 205-218, 2001 | 157 | 2001 |
| Predominant expression of Alzheimer’s disease-associated BIN1 in mature oligodendrocytes and localization to white matter tracts P De Rossi, V Buggia-Prévot, BLL Clayton, JB Vasquez, C Van Sanford, ... Molecular neurodegeneration 11, 1-21, 2016 | 137 | 2016 |
| Synaptic transmission and hippocampal long-term potentiation in transgenic mice expressing FAD-linked presenilin 1 A Parent, DJ Linden, SS Sisodia, DR Borchelt Neurobiology of disease 6 (1), 56-62, 1999 | 137 | 1999 |
| APP receptor? To be or not to be C Deyts, G Thinakaran, AT Parent Trends in pharmacological sciences 37 (5), 390-411, 2016 | 127 | 2016 |
| Mechanisms of disease: new therapeutic strategies for Alzheimer's disease—targeting APP processing in lipid rafts H Cheng, KS Vetrivel, P Gong, X Meckler, A Parent, G Thinakaran Nature Clinical Practice Neurology 3 (7), 374-382, 2007 | 127 | 2007 |
| Identification of the role of presenilins beyond Alzheimer’s disease G Thinakaran, AT Parent Pharmacological research 50 (4), 411-418, 2004 | 99 | 2004 |
| A function for EHD family proteins in unidirectional retrograde dendritic transport of BACE1 and Alzheimer’s disease Aβ production V Buggia-Prevot, CG Fernandez, V Udayar, KS Vetrivel, A Elie, ... Cell reports 5 (6), 1552-1563, 2013 | 86 | 2013 |
| Presenilin attenuates receptor-mediated signaling and synaptic function AT Parent, NY Barnes, Y Taniguchi, G Thinakaran, SS Sisodia Journal of Neuroscience 25 (6), 1540-1549, 2005 | 86 | 2005 |
| Endothelin vascular receptors and responses in deoxycorticosterone acetate-salt hypertensive rats. PV Nguyen, A Parent, LY Deng, JP Flückiger, G Thibault, EL Schiffrin Hypertension 19 (2_supplement), II98, 1992 | 83 | 1992 |
| Blunted responses to vasoconstrictors in mesenteric vasculature but not in portal vein of spontaneously hypertensive rats treated with relaxin G Massicotte, A Parent, J St-Louis Proceedings of the Society for Experimental Biology and Medicine 190 (3 …, 1989 | 79 | 1989 |
| Enhanced synaptic potentiation in transgenic mice expressing presenilin 1 familial Alzheimer's disease mutation is normalized with a benzodiazepine SH Zaman, A Parent, A Laskey, MK Lee, DR Borchelt, SS Sisodia, ... Neurobiology of disease 7 (1), 54-63, 2000 | 78 | 2000 |
| Evidence That CD147 Modulation of β-Amyloid (Aβ) Levels Is Mediated by Extracellular Degradation of Secreted Aβ*♦ KS Vetrivel, X Zhang, X Meckler, H Cheng, S Lee, P Gong, KO Lopes, ... Journal of Biological Chemistry 283 (28), 19489-19498, 2008 | 75 | 2008 |
| Lack of BACE1 S-palmitoylation reduces amyloid burden and mitigates memory deficits in transgenic mouse models of Alzheimer’s disease RJ Andrew, CG Fernandez, M Stanley, H Jiang, P Nguyen, RC Rice, ... Proceedings of the National Academy of Sciences 114 (45), E9665-E9674, 2017 | 71 | 2017 |
| Novel GαS-protein signaling associated with membrane-tethered amyloid precursor protein intracellular domain C Deyts, KS Vetrivel, S Das, YM Shepherd, DJ Dupré, G Thinakaran, ... Journal of Neuroscience 32 (5), 1714-1729, 2012 | 60 | 2012 |
| Role of the endothelium in adrenergic responses of mesenteric artery rings of pregnant rats A Parent, EL Schiffrin, J St-Louis American journal of obstetrics and gynecology 163 (1), 229-234, 1990 | 55 | 1990 |