arrow encodes an LDL-receptor-related protein essential for Wingless signalling M Wehrli, ST Dougan, K Caldwell, L O'Keefe, S Schwartz, ... Nature 407 (6803), 527-530, 2000 | 1189 | 2000 |
A putative exchange factor for Rho1 GTPase is required for initiation of cytokinesis in Drosophila SN Prokopenko, A Brumby, L O’Keefe, L Prior, Y He, R Saint, HJ Bellen Genes & development 13 (17), 2301-2314, 1999 | 316 | 1999 |
Ectopic cyclin E expression induces premature entry into S phase and disrupts pattern formation in the Drosophila eye imaginal disc H Richardson, LV O’Keefe, T Marty Development 121 (10), 3371-3379, 1995 | 240 | 1995 |
A Drosophila G1-specific cyclin E homolog exhibits different modes of expression during embryogenesis HE Richardson, LV O’Keefe, SI Reed, R Saint Development 119 (3), 673-690, 1993 | 177 | 1993 |
Spitz and Wingless, emanating from distinct borders, cooperate to establish cell fate across the Engrailed domain in the Drosophila epidermis L O’Keefe, ST Dougan, L Gabay, E Raz, BZ Shilo, S DiNardo Development 124 (23), 4837-4845, 1997 | 102 | 1997 |
Common chromosomal fragile sites and cancer: focus on FRA16D LV O'Keefe, RI Richards Cancer letters 232 (1), 37-47, 2006 | 100 | 2006 |
Regulation of the elongation phase of protein synthesis enhances translation accuracy and modulates lifespan J Xie, V de Souza Alves, T von der Haar, L O’Keefe, RV Lenchine, ... Current Biology 29 (5), 737-749. e5, 2019 | 76 | 2019 |
CRISPR/Cas9‐mediated mutagenesis of the white gene in the tephritid pest Bactrocera tryoni A Choo, P Crisp, R Saint, LV O'Keefe, SW Baxter Journal of Applied Entomology 142 (1-2), 52-58, 2018 | 64 | 2018 |
Drosophila orthologue of WWOX, the chromosomal fragile site FRA16D tumour suppressor gene, functions in aerobic metabolism and regulates reactive oxygen … LV O'Keefe, A Colella, S Dayan, Q Chen, A Choo, R Jacob, G Price, ... Human molecular genetics 20 (3), 497-509, 2011 | 60 | 2011 |
Double-stranded RNA is pathogenic in Drosophila models of expanded repeat neurodegenerative diseases KT Lawlor, LV O'Keefe, SE Samaraweera, CL Van Eyk, CJ McLeod, ... Human Molecular Genetics 20 (19), 3757-3768, 2011 | 59 | 2011 |
Chromosomal instability causes sensitivity to metabolic stress Z Shaukat, D Liu, A Choo, R Hussain, L O'Keefe, R Richards, R Saint, ... Oncogene 34 (31), 4044-4055, 2015 | 52 | 2015 |
The pathogenic agent in Drosophila models of ‘polyglutamine’ diseases CJ McLeod, LV O'Keefe, RI Richards Human molecular genetics 14 (8), 1041-1048, 2005 | 46 | 2005 |
The enemy within: innate surveillance-mediated cell death, the common mechanism of neurodegenerative disease RI Richards, SA Robertson, LV O'Keefe, D Fornarino, A Scott, M Lardelli, ... Frontiers in neuroscience 10, 193, 2016 | 43 | 2016 |
A Drosophila Overexpression Screen for Modifiers of Rho Signalling in Cytokinesis SL Gregory, T Shandala, L O'Keefe, L Jones, MJ Murray, RB Saint Fly 1 (1), 13-22, 2007 | 43 | 2007 |
The pebble GTP exchange factor and the control of cytokinesis L O'keefe, WG Somers, A Harley, R Saint Cell structure and function 26 (6), 619-626, 2001 | 42 | 2001 |
Perturbation of the Akt/Gsk3-β signalling pathway is common to Drosophila expressing expanded untranslated CAG, CUG and AUUCU repeat RNAs CL Van Eyk, LV O'Keefe, KT Lawlor, SE Samaraweera, CJ McLeod, ... Human molecular genetics 20 (14), 2783-2794, 2011 | 33 | 2011 |
FRA16D common chromosomal fragile site oxido-reductase (FOR/WWOX) protects against the effects of ionizing radiation in Drosophila LV O'Keefe, Y Liu, A Perkins, S Dayan, R Saint, RI Richards Oncogene 24 (43), 6590-6596, 2005 | 28 | 2005 |
WWOX, the chromosomal fragile site FRA16D spanning gene: Its role in metabolism and contribution to cancer RI Richards, A Choo, CS Lee, S Dayan, L O’Keefe Experimental Biology and Medicine 240 (3), 338-344, 2015 | 27 | 2015 |
Common chromosomal fragile site FRA16D tumor suppressor WWOX gene expression and metabolic reprograming in cells S Dayan, LV O'Keefe, A Choo, RI Richards Genes, Chromosomes and Cancer 52 (9), 823-831, 2013 | 25 | 2013 |
Distinct roles for Toll and autophagy pathways in double-stranded RNA toxicity in a Drosophila model of expanded repeat neurodegenerative diseases SE Samaraweera, LV O'Keefe, GR Price, DJ Venter, RI Richards Human Molecular Genetics 22 (14), 2811-2819, 2013 | 25 | 2013 |