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Adrien Moreau
Adrien Moreau
PhyMedExp Montpellier
Correu electrònic verificat a ens-lyon.fr
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Biophysics, Pathophysiology and Pharmacology of Ion Channel Gating Pores
A Moreau, P Gosselin-Badaroudine, M Chahine
Pharmacology of Ion Channels and Channelopathies 5, 53, 2014
902014
Gating pore currents are defects in common with two Nav1.5 mutations in patients with mixed arrhythmias and dilated cardiomyopathy
A Moreau, P Gosselin-Badaroudine, L Delemotte, ML Klein, M Chahine
Journal of General Physiology 145 (2), 93-106, 2015
882015
Gating pore currents and the resting state of Nav1. 4 voltage sensor domains
P Gosselin-Badaroudine, L Delemotte, A Moreau, ML Klein, M Chahine
Proceedings of the National Academy of Sciences 109 (47), 19250-19255, 2012
882012
Post-translational modifications and diastolic calcium leak associated to the novel RyR2-D3638A mutation lead to CPVT in patient-specific hiPSC-derived cardiomyocytes
I Acimovic, MM Refaat, A Moreau, A Salykin, S Reiken, Y Sleiman, ...
Journal of clinical medicine 7 (11), 423, 2018
532018
Mutations in the Voltage Sensors of Domains I and II of Nav1.5 that are Associated with Arrhythmias and Dilated Cardiomyopathy Generate Gating Pore Currents
A Moreau, P Gosselin-Badaroudine, M Boutjdir, M Chahine
Frontiers in Pharmacology 6, 301, 2015
532015
A leaky voltage sensor domain of cardiac sodium channels causes arrhythmias associated with dilated cardiomyopathy
A Moreau, P Gosselin-Badaroudine, A Mercier, B Burger, DI Keller, ...
Scientific reports 8 (1), 13804, 2018
412018
Nav1. 5 mutations linked to dilated cardiomyopathy phenotypes: Is the gating pore current the missing link?
P Gosselin-Badaroudine, A Moreau, M Chahine
Channels 8 (1), 90-94, 2014
402014
Mexiletine differentially restores the trafficking defects caused by two brugada syndrome mutations
A Moreau, DI Keller, H Huang, V Fressart, C Schmied, Q Timour, ...
Frontiers in Pharmacology 3, 62, 2012
392012
Characterization of the honeybee AmNaV1 channel and tools to assess the toxicity of insecticides
P Gosselin-Badaroudine, A Moreau, L Delemotte, T Cens, C Collet, ...
Scientific Reports 5 (1), 12475, 2015
312015
Biophysical, molecular, and pharmacological characterization of voltage-dependent sodium channels from induced pluripotent stem cell-derived cardiomyocytes
A Moreau, A Mercier, O Thériault, M Boutjdir, B Burger, DI Keller, ...
Canadian Journal of Cardiology 33 (2), 269-278, 2017
302017
Molecular biology and biophysical properties of ion channel gating pores
A Moreau, P Gosselin-Badaroudine, M Chahine
Quarterly reviews of biophysics 47 (4), 364-388, 2014
282014
Sodium overload due to a persistent current that attenuates the arrhythmogenic potential of a novel LQT3 mutation
A Moreau, AD Krahn, P Gosselin-Badaroudine, GJ Klein, G Christé, ...
Frontiers in pharmacology 4, 126, 2013
262013
Modeling polymorphic ventricular tachycardia at rest using patient-specific induced pluripotent stem cell-derived cardiomyocytes
Y Sleiman, M Souidi, R Kumar, E Yang, F Jaffré, T Zhou, A Bernardin, ...
EBioMedicine 60, 2020
232020
A New Cardiac Channelopathy: From Clinical Phenotypes to Molecular Mechanisms Associated With Nav1.5 Gating Pores
A Moreau, M Chahine
Frontiers in cardiovascular medicine 5, 139, 2018
232018
Biophysical characterization of the honeybee DSC1 orthologue reveals a novel voltage-dependent Ca2+ channel subfamily: CaV4
P Gosselin-Badaroudine, A Moreau, L Simard, T Cens, M Rousset, ...
Journal of General Physiology 148 (2), 133-145, 2016
232016
Deciphering DSC2 arrhythmogenic cardiomyopathy electrical instability: From ion channels to ECG and tailored drug therapy
A Moreau, JB Reisqs, H Delanoe‐Ayari, M Pierre, A Janin, A Deliniere, ...
Clinical and translational medicine 11 (3), e319, 2021
222021
Cardiac voltage-gated sodium channel mutations associated with left atrial dysfunction and stroke in children
A Moreau, A Janin, G Millat, P Chevalier
Ep Europace 20 (10), 1692-1698, 2018
202018
Gating pore currents in sodium channels
JR Groome, A Moreau, L Delemotte
Voltage-gated Sodium Channels: Structure, Function and Channelopathies, 371-399, 2018
182018
The PPARγ pathway determines electrophysiological remodelling and arrhythmia risks in DSC2 arrhythmogenic cardiomyopathy
JB Reisqs, A Moreau, A Charrabi, Y Sleiman, AC Meli, G Millat, V Briand, ...
Clinical and Translational Medicine 12 (3), e748, 2022
152022
Blockade of the renin‐angiotensin‐aldosterone system in patients with arrhythmogenic right ventricular dysplasia: A double‐blind, multicenter, prospective, randomized, genotype …
E Morel, AW Manati, P Nony, D Maucort‐Boulch, F Bessière, X Cai, ...
Clinical Cardiology 41 (3), 300-306, 2018
142018
En aquests moments el sistema no pot dur a terme l'operació. Torneu-ho a provar més tard.
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