| Inflammation, stress, and diabetes KE Wellen, GS Hotamisligil The Journal of clinical investigation 115 (5), 1111-1119, 2005 | 5800 | 2005 |
| Obesity-induced inflammatory changes in adipose tissue KE Wellen, GS Hotamisligil The Journal of clinical investigation 112 (12), 1785-1788, 2003 | 2523 | 2003 |
| ATP-citrate lyase links cellular metabolism to histone acetylation KE Wellen, G Hatzivassiliou, UM Sachdeva, TV Bui, JR Cross, ... Science 324 (5930), 1076-1080, 2009 | 2320 | 2009 |
| IDH mutation impairs histone demethylation and results in a block to cell differentiation C Lu, PS Ward, GS Kapoor, D Rohle, S Turcan, O Abdel-Wahab, ... Nature 483 (7390), 474-478, 2012 | 2244 | 2012 |
| Akt-dependent metabolic reprogramming regulates tumor cell histone acetylation JV Lee, A Carrer, S Shah, NW Snyder, S Wei, S Venneti, AJ Worth, ... Cell metabolism 20 (2), 306-319, 2014 | 595 | 2014 |
| Cellular metabolic stress: considering how cells respond to nutrient excess KE Wellen, CB Thompson Molecular cell 40 (2), 323-332, 2010 | 579 | 2010 |
| A two-way street: reciprocal regulation of metabolism and signalling KE Wellen, CB Thompson Nature reviews Molecular cell biology 13 (4), 270-276, 2012 | 562 | 2012 |
| Reciprocal regulation of p53 and malic enzymes modulates metabolism and senescence P Jiang, W Du, A Mancuso, KE Wellen, X Yang Nature 493 (7434), 689-693, 2013 | 545 | 2013 |
| Epigenomic reprogramming during pancreatic cancer progression links anabolic glucose metabolism to distant metastasis OG McDonald, X Li, T Saunders, R Tryggvadottir, SJ Mentch, ... Nature genetics 49 (3), 367-376, 2017 | 462 | 2017 |
| Metabolic reprogramming in cancer: unraveling the role of glutamine in tumorigenesis D Daye, KE Wellen Seminars in cell & developmental biology 23 (4), 362-369, 2012 | 461 | 2012 |
| The hexosamine biosynthetic pathway couples growth factor-induced glutamine uptake to glucose metabolism KE Wellen, C Lu, A Mancuso, JMS Lemons, M Ryczko, JW Dennis, ... Genes & development 24 (24), 2784-2799, 2010 | 458 | 2010 |
| Dietary fructose feeds hepatic lipogenesis via microbiota-derived acetate S Zhao, C Jang, J Liu, K Uehara, M Gilbert, L Izzo, X Zeng, S Trefely, ... Nature 579 (7800), 586-591, 2020 | 441 | 2020 |
| Metabolic control of epigenetics in cancer A Kinnaird, S Zhao, KE Wellen, ED Michelakis Nature Reviews Cancer 16 (11), 694-707, 2016 | 424 | 2016 |
| ATP-citrate lyase controls a glucose-to-acetate metabolic switch S Zhao, AM Torres, RA Henry, S Trefely, M Wallace, JV Lee, A Carrer, ... Cell reports 17 (4), 1037-1052, 2016 | 396 | 2016 |
| Acetate production from glucose and coupling to mitochondrial metabolism in mammals X Liu, DE Cooper, AA Cluntun, MO Warmoes, S Zhao, MA Reid, J Liu, ... Cell 175 (2), 502-513. e13, 2018 | 358 | 2018 |
| Dysregulated metabolism contributes to oncogenesis MD Hirschey, RJ DeBerardinis, AME Diehl, JE Drew, C Frezza, MF Green, ... Seminars in cancer biology 35, S129-S150, 2015 | 328 | 2015 |
| Designing a broad-spectrum integrative approach for cancer prevention and treatment KI Block, C Gyllenhaal, L Lowe, A Amedei, ARMR Amin, A Amin, ... Seminars in cancer biology 35, S276-S304, 2015 | 324 | 2015 |
| Spatiotemporal control of acetyl-CoA metabolism in chromatin regulation S Sivanand, I Viney, KE Wellen Trends in biochemical sciences 43 (1), 61-74, 2018 | 302 | 2018 |
| Metabolic control of methylation and acetylation X Su, KE Wellen, JD Rabinowitz Current opinion in chemical biology 30, 52-60, 2016 | 285 | 2016 |
| Acetyl-CoA metabolism supports multistep pancreatic tumorigenesis A Carrer, S Trefely, S Zhao, SL Campbell, RJ Norgard, KC Schultz, ... Cancer discovery 9 (3), 416-435, 2019 | 279 | 2019 |
