Segueix
Fabian Dingfelder
Fabian Dingfelder
Analytical Development Department, Johnson & Johnson
Correu electrònic verificat a its.jnj.com
Títol
Citada per
Citada per
Any
Single-molecule spectroscopy of protein conformational dynamics in live eukaryotic cells
I König, A Zarrine-Afsar, M Aznauryan, A Soranno, B Wunderlich, ...
nAture methods 12 (8), 773-779, 2015
2782015
Machine learning for biologics: opportunities for protein engineering, developability, and formulation
H Narayanan, F Dingfelder, A Butté, N Lorenzen, M Sokolov, P Arosio
Trends in pharmacological sciences 42 (3), 151-165, 2021
1282021
Integrated view of internal friction in unfolded proteins from single-molecule FRET, contact quenching, theory, and simulations
A Soranno, A Holla, F Dingfelder, D Nettels, DE Makarov, B Schuler
Biophysical Journal 112 (3), 318a, 2017
1122017
Design of biopharmaceutical formulations accelerated by machine learning
H Narayanan, F Dingfelder, I Condado Morales, B Patel, KE Heding, ...
Molecular Pharmaceutics 18 (10), 3843-3853, 2021
632021
Rapid microfluidic dilution for single‐molecule spectroscopy of low‐affinity biomolecular complexes
N Zijlstra, F Dingfelder, B Wunderlich, F Zosel, S Benke, D Nettels, ...
Angewandte Chemie International Edition 56 (25), 7126-7129, 2017
262017
Mapping an equilibrium folding intermediate of the cytolytic pore toxin ClyA with single-molecule FRET
F Dingfelder, S Benke, D Nettels, B Schuler
The Journal of Physical Chemistry B 122 (49), 11251-11261, 2018
252018
Rapid microfluidic double-jump mixing device for single-molecule spectroscopy
F Dingfelder, B Wunderlich, S Benke, F Zosel, N Zijlstra, D Nettels, ...
Journal of the American Chemical Society 139 (17), 6062-6065, 2017
202017
Slow escape from a helical misfolded state of the pore-forming toxin cytolysin A
F Dingfelder, I Macocco, S Benke, D Nettels, P Faccioli, B Schuler
JACS Au 1 (8), 1217-1230, 2021
112021
Measuring self-association of antibody lead candidates with dynamic light scattering
F Dingfelder, A Henriksen, PO Wahlund, P Arosio, N Lorenzen
Therapeutic Antibodies: Methods and Protocols, 241-258, 2022
92022
A comparative study of the developability of full-length antibodies, fragments, and bispecific formats reveals higher stability risks for engineered constructs
I Condado-Morales, F Dingfelder, I Waibel, OM Turnbull, B Patel, Z Cao, ...
MAbs 16 (1), 2403156, 2024
32024
Microfluidic stress device to decouple the synergistic effect of shear and interfaces on antibody aggregation
MS Gerlt, EM Meier, F Dingfelder, D Zürcher, M Müller, P Arosio
Journal of Pharmaceutical Sciences 113 (8), 2161-2169, 2024
32024
Portable microfluidic viscometer for formulation development and in situ quality control of protein and antibody solutions
PS Lenzen, F Dingfelder, M Müller, P Arosio
Analytical Chemistry 96 (32), 13185-13190, 2024
12024
Microfluidic Devices for Probing Protein Dynamics with Single-Molecule Spectroscopy
F Dingfelder
University of Zurich, 2018
2018
RDC-basierte Strukturverfeinerung von NfeD-ß-Barrel-Domänen
F Dingfelder
2011
Graduate School of Chemical and Molecular Sciences Zurich
R Alberto, S Bienz, L Bigler, EC Böttger, H Braband, D Brühwiler, ...
En aquests moments el sistema no pot dur a terme l'operació. Torneu-ho a provar més tard.
Articles 1–15