| Structure and mechanism of the CMR complex for CRISPR-mediated antiviral immunity J Zhang, C Rouillon, M Kerou, J Reeks, K Brugger, S Graham, J Reimann, ... Molecular cell 45 (3), 303-313, 2012 | 472 | 2012 |
| Three-dimensional structure of the human DNA-PKcs/Ku70/Ku80 complex assembled on DNA and its implications for DNA DSB repair L Spagnolo, A Rivera-Calzada, LH Pearl, O Llorca Molecular cell 22 (4), 511-519, 2006 | 350 | 2006 |
| Structure of the CRISPR interference complex CSM reveals key similarities with cascade C Rouillon, M Zhou, J Zhang, A Politis, V Beilsten-Edmands, G Cannone, ... Molecular cell 52 (1), 124-134, 2013 | 262 | 2013 |
| Structural model of full‐length human Ku70–Ku80 heterodimer and its recognition of DNA and DNA‐PKcs A Rivera‐Calzada, L Spagnolo, LH Pearl, O Llorca EMBO reports 8 (1), 56-62, 2007 | 155 | 2007 |
| Conformational strain in the hydrophobic core and its implications for protein folding and design S Ventura, M Cristina Vega, E Lacroix, I Angrand, L Spagnolo, L Serrano Nature structural biology 9 (6), 485-493, 2002 | 137 | 2002 |
| Three-dimensional structure and regulation of the DNA-dependent protein kinase catalytic subunit (DNA-PKcs) A Rivera-Calzada, JP Maman, L Spagnolo, LH Pearl, O Llorca Structure 13 (2), 243-255, 2005 | 135 | 2005 |
| Visualization of a DNA-PK/PARP1 complex L Spagnolo, J Barbeau, NJ Curtin, EP Morris, LH Pearl Nucleic acids research 40 (9), 4168-4177, 2012 | 125 | 2012 |
| Unique features of the sodC-encoded superoxide dismutase from Mycobacterium tuberculosis, a fully functional copper-containing enzyme lacking zinc in the active site L Spagnolo, I Törö, M D'orazio, P O'Neill, JZ Pedersen, O Carugo, ... Journal of Biological Chemistry 279 (32), 33447-33455, 2004 | 119 | 2004 |
| Cyclic nucleotide-induced helical structure activates a TIR immune effector G Hogrel, A Guild, S Graham, H Rickman, S Grüschow, Q Bertrand, ... Nature 608 (7924), 808-812, 2022 | 88 | 2022 |
| PARP power: a structural perspective on PARP1, PARP2, and PARP3 in DNA damage repair and nucleosome remodelling L van Beek, É McClay, S Patel, M Schimpl, L Spagnolo, ... International journal of molecular sciences 22 (10), 5112, 2021 | 77 | 2021 |
| Differential functions of FANCI and FANCD2 ubiquitination stabilize ID2 complex on DNA ML Rennie, K Lemonidis, C Arkinson, VK Chaugule, M Clarke, J Streetley, ... EMBO reports 21 (7), e50133, 2020 | 40 | 2020 |
| Photobacterium profundum under pressure: a MS-based label-free quantitative proteomics study T Le Bihan, J Rayner, MM Roy, L Spagnolo PLoS One 8 (5), e60897, 2013 | 37 | 2013 |
| Evidence for a remodelling of DNA-PK upon autophosphorylation from electron microscopy studies EP Morris, A Rivera-Calzada, PCA da Fonseca, O Llorca, LH Pearl, ... Nucleic acids research 39 (13), 5757-5767, 2011 | 27 | 2011 |
| Crystal structures of malonyl-coenzyme A decarboxylase provide insights into its catalytic mechanism and disease-causing mutations DS Froese, F Forouhar, TH Tran, M Vollmar, YS Kim, S Lew, H Neely, ... Structure 21 (7), 1182-1192, 2013 | 21 | 2013 |
| The architecture of an Okazaki fragment-processing holoenzyme from the archaeon Sulfolobus solfataricus G Cannone, Y Xu, TR Beattie, SD Bell, L Spagnolo Biochemical Journal, 2015 | 19 | 2015 |
| Folding specificity induced by loop stiffness L Spagnolo, S Ventura, L Serrano Protein science 12 (7), 1473-1482, 2003 | 8 | 2003 |
| A multipronged approach to understanding the form and function of hStaufen protein S Visentin, G Cannone, J Doutch, G Harris, ML Gleghorn, L Clifton, ... RNA 26 (3), 265-277, 2020 | 6 | 2020 |
| Structure of an octameric form of the minichromosome maintenance protein from the archaeon Pyrococcus abyssi G Cannone, S Visentin, A Palud, G Henneke, L Spagnolo Scientific Reports 7 (1), 42019, 2017 | 5 | 2017 |
| Electron microscopy studies of Type III CRISPR machines in Sulfolobus solfataricus G Cannone, M Webber-Birungi, L Spagnolo Biochemical Society Transactions 41 (6), 1427-1430, 2013 | 5 | 2013 |
| Structure of the Saccharolobus solfataricus type III-D CRISPR effector G Cannone, D Kompaniiets, S Graham, MF White, L Spagnolo Current Research in Structural Biology 5, 100098, 2023 | 4 | 2023 |
Malcolm F WhiteUniversity of St AndrewsCorreu electrònic verificat a st-and.ac.uk