Extracellular vesicles from human iPSC-derived neural stem cells: miRNA and protein signatures, and anti-inflammatory and neurogenic properties R Upadhya, LN Madhu, S Attaluri, DLG Gitaí, MR Pinson, M Kodali, ... Journal of extracellular vesicles 9 (1), 1809064, 2020 | 142 | 2020 |
Emerging anti-aging strategies-scientific basis and efficacy AK Shetty, M Kodali, R Upadhya, LN Madhu Aging and disease 9 (6), 1165, 2018 | 137 | 2018 |
Metformin treatment in late middle age improves cognitive function with alleviation of microglial activation and enhancement of autophagy in the hippocampus M Kodali, S Attaluri, LN Madhu, B Shuai, R Upadhya, JJ Gonzalez, X Rao, ... Aging Cell 20 (2), e13277, 2021 | 118 | 2021 |
Intranasally administered human MSC-derived extracellular vesicles pervasively incorporate into neurons and microglia in both intact and status epilepticus injured forebrain M Kodali, OW Castro, DK Kim, A Thomas, B Shuai, S Attaluri, R Upadhya, ... International journal of molecular sciences 21 (1), 181, 2019 | 103 | 2019 |
Melatonin improves brain function in a model of chronic Gulf War Illness with modulation of oxidative stress, NLRP3 inflammasomes, and BDNF-ERK-CREB pathway in the hippocampus LN Madhu, M Kodali, S Attaluri, B Shuai, L Melissari, X Rao, AK Shetty Redox Biology 43, 101973, 2021 | 86 | 2021 |
Neuroinflammation in Gulf War Illness is linked with HMGB1 and complement activation, which can be discerned from brain-derived extracellular vesicles in the blood LN Madhu, S Attaluri, M Kodali, B Shuai, R Upadhya, D Gitai, AK Shetty Brain, behavior, and immunity 81, 430-443, 2019 | 85 | 2019 |
Monosodium luminol reinstates redox homeostasis, improves cognition, mood and neurogenesis, and alleviates neuro-and systemic inflammation in a model of Gulf War Illness AK Shetty, S Attaluri, M Kodali, B Shuai, GA Shetty, D Upadhya, ... Redox biology 28, 101389, 2020 | 61 | 2020 |
Intranasally administered human MSC-derived extracellular vesicles inhibit NLRP3-p38/MAPK signaling after TBI and prevent chronic brain dysfunction M Kodali, LN Madhu, RL Reger, B Milutinovic, R Upadhya, JJ Gonzalez, ... Brain, behavior, and immunity 108, 118-134, 2023 | 57 | 2023 |
Gulf War illness: mechanisms underlying brain dysfunction and promising therapeutic strategies B Dickey, LN Madhu, AK Shetty Pharmacology & therapeutics 220, 107716, 2021 | 56 | 2021 |
Rapid synthesis of gold nanoparticles using silk fibroin: characterization, antibacterial activity, and anticancer properties B Lakshmeesha Rao, M Gowda, S Asha, K Byrappa, B Narayana, ... Gold Bulletin 50, 289-297, 2017 | 45 | 2017 |
Synthesis of new pyrazole derivatives via multicomponent reaction and evaluation of their antimicrobial and antioxidant activities S Viveka, Dinesha, LN Madhu, GK Nagaraja Monatshefte für Chemie-Chemical Monthly 146, 1547-1555, 2015 | 44 | 2015 |
Promise of irisin to attenuate cognitive dysfunction in aging and Alzheimer’s disease LN Madhu, Y Somayaji, AK Shetty Ageing research reviews 78, 101637, 2022 | 33 | 2022 |
Novel insights on systemic and brain aging, stroke, amyotrophic lateral sclerosis, and Alzheimer’s disease AK Shetty, R Upadhya, LN Madhu, M Kodali Aging and disease 10 (2), 470, 2019 | 33 | 2019 |
Promise of metformin for preventing age-related cognitive dysfunction LN Madhu, M Kodali, AK Shetty Neural Regeneration Research 17 (3), 503-507, 2022 | 31 | 2022 |
Extracellular vesicles in the forebrain display reduced miR-346 and miR-331-3p in a rat model of chronic temporal lobe epilepsy DLG Gitaí, YDR Dos Santos, R Upadhya, M Kodali, LN Madhu, AK Shetty Molecular neurobiology 57, 1674-1687, 2020 | 27 | 2020 |
Synthesis of new indazole derivatives as potential antioxidant agents M Sapnakumari, B Narayana, BK Sarojini, LN Madhu Medicinal chemistry research 23, 2368-2376, 2014 | 27 | 2014 |
Oral nano-curcumin in a model of chronic Gulf War illness alleviates brain dysfunction with modulation of oxidative stress, mitochondrial function, neuroinflammation … S Attaluri, M Arora, LN Madhu, M Kodali, B Shuai, L Melissari, R Upadhya, ... Aging and Disease 13 (2), 583, 2022 | 24 | 2022 |
A study on the reactions of alkyl 4, 6-bis (4-fluorophenyl)-2-oxocyclohex-3-ene-1-carboxylate and in vitro antioxidant activity of derivatives S Samshuddin, B Narayana, BK Sarojini, LN Madhu Medicinal Chemistry Research 22, 3002-3011, 2013 | 24 | 2013 |
Synthesis, molecular docking and biological evaluation of novel bis-pyrazole derivatives for analgesic, anti-inflammatory and antimicrobial activities PS Nayak, B Narayana, BK Sarojini, J Fernades, BR Bharath, LN Madhu Medicinal Chemistry Research 24, 4191-4206, 2015 | 19 | 2015 |
Intranasally administered extracellular vesicles from human induced pluripotent stem cell-derived neural stem cells quickly incorporate into neurons and microglia in 5xFAD mice S Attaluri, J Jaimes Gonzalez, M Kirmani, AD Vogel, R Upadhya, M Kodali, ... Frontiers in Aging Neuroscience 15, 1200445, 2023 | 18 | 2023 |