Regulation of tumor pH and the role of carbonic anhydrase 9 P Swietach, RD Vaughan-Jones, AL Harris Cancer and Metastasis Reviews 26 (2), 299-310, 2007 | 703 | 2007 |
The chemistry, physiology and pathology of pH in cancer P Swietach, RD Vaughan-Jones, AL Harris, A Hulikova Philosophical transactions of the royal society B: biological sciences 369 …, 2014 | 592 | 2014 |
The role of carbonic anhydrase 9 in regulating extracellular and intracellular ph in three-dimensional tumor cell growths P Swietach, S Patiar, CT Supuran, AL Harris, RD Vaughan-Jones Journal of Biological Chemistry 284 (30), 20299-20310, 2009 | 331 | 2009 |
Intracellular pH regulation in heart RD Vaughan-Jones, KW Spitzer, P Swietach Journal of molecular and cellular cardiology 46 (3), 318-331, 2009 | 317 | 2009 |
Carbonic anhydrase IX promotes tumor growth and necrosis in vivo and inhibition enhances anti-VEGF therapy A McIntyre, S Patiar, S Wigfield, J Li, I Ledaki, H Turley, R Leek, C Snell, ... Clinical cancer research 18 (11), 3100-3111, 2012 | 290 | 2012 |
New insights into the physiological role of carbonic anhydrase IX in tumour pH regulation P Swietach, A Hulikova, RD Vaughan-Jones, AL Harris Oncogene 29 (50), 6509-6521, 2010 | 279 | 2010 |
Evidence-based guidelines for controlling pH in mammalian live-cell culture systems J Michl, KC Park, P Swietach Communications biology 2 (1), 144, 2019 | 261 | 2019 |
Tumor-associated carbonic anhydrase 9 spatially coordinates intracellular pH in three-dimensional multicellular growths P Swietach, S Wigfield, P Cobden, CT Supuran, AL Harris, ... Journal of biological chemistry 283 (29), 20473-20483, 2008 | 237 | 2008 |
Measuring intracellular pH in the heart using hyperpolarized carbon dioxide and bicarbonate: a 13C and 31P magnetic resonance spectroscopy study MA Schroeder, P Swietach, HJ Atherton, FA Gallagher, P Lee, GK Radda, ... Cardiovascular research 86 (1), 82-91, 2010 | 168 | 2010 |
Importance of intracellular pH in determining the uptake and efficacy of the weakly basic chemotherapeutic drug, doxorubicin P Swietach, A Hulikova, S Patiar, RD Vaughan-Jones, AL Harris PloS one 7 (4), e35949, 2012 | 141 | 2012 |
Off-target effects of sodium-glucose co-transporter 2 blockers: empagliflozin does not inhibit Na+/H+ exchanger-1 or lower [Na+]i in the heart YJ Chung, KC Park, S Tokar, TR Eykyn, W Fuller, D Pavlovic, P Swietach, ... Cardiovascular research 117 (14), 2794-2806, 2021 | 133 | 2021 |
T-cells produce acidic niches in lymph nodes to suppress their own effector functions H Wu, V Estrella, M Beatty, D Abrahams, A El-Kenawi, S Russell, ... Nature communications 11 (1), 4113, 2020 | 133 | 2020 |
Regulation of intracellular pH in cancer cell lines under normoxia and hypoxia A Hulikova, AL Harris, RD Vaughan‐Jones, P Swietach Journal of cellular physiology 228 (4), 743-752, 2013 | 128 | 2013 |
What is pH regulation, and why do cancer cells need it? P Swietach Cancer and Metastasis Reviews 38, 5-15, 2019 | 125 | 2019 |
S0859, an N‐cyanosulphonamide inhibitor of sodium‐bicarbonate cotransport in the heart FFT Ch'En, FC Villafuerte, P Swietach, PM Cobden, RD Vaughan‐Jones British journal of pharmacology 153 (5), 972-982, 2008 | 125 | 2008 |
Coupled Ca2+/H+ transport by cytoplasmic buffers regulates local Ca2+ and H+ ion signaling P Swietach, JB Youm, N Saegusa, CH Leem, KW Spitzer, ... Proceedings of the National Academy of Sciences 110 (22), E2064-E2073, 2013 | 121 | 2013 |
Dual role of CO2/HCO3− buffer in the regulation of intracellular pH of three-dimensional tumor growths A Hulikova, RD Vaughan-Jones, P Swietach Journal of Biological Chemistry 286 (16), 13815-13826, 2011 | 111 | 2011 |
Carbonic anhydrase IX is a pH-stat that sets an acidic tumour extracellular pH in vivo SH Lee, D McIntyre, D Honess, A Hulikova, J Pacheco-Torres, S Cerdán, ... British Journal of Cancer 119 (5), 622-630, 2018 | 110 | 2018 |
Hydrogen ion dynamics in human red blood cells P Swietach, T Tiffert, JMA Mauritz, R Seear, A Esposito, CF Kaminski, ... The Journal of physiology 588 (24), 4995-5014, 2010 | 110 | 2010 |
Disrupting hypoxia-induced bicarbonate transport acidifies tumor cells and suppresses tumor growth A McIntyre, A Hulikova, I Ledaki, C Snell, D Singleton, G Steers, P Seden, ... Cancer research 76 (13), 3744-3755, 2016 | 99 | 2016 |