| A member of the gut mycobiota modulates host purine metabolism exacerbating colitis in mice JLR Tyson R. Chiaro, Ray Soto, W. Zac Stephens, Jason L. Kubinak, Charisse ... Science Translational Medicine 9 (380), eaaf9044, 2017 | 223 | 2017 |
| A heritable switch in carbon source utilization driven by an unusual yeast prion JCS Brown, S Lindquist Genes & development 23 (19), 2320-2332, 2009 | 209 | 2009 |
| Cross-Kingdom Chemical Communication Drives a Heritable, Mutually Beneficial Prion-Based Transformation of Metabolism DF Jarosz, J Brown, GA Walker, MS Datta, WL Ung, AK Lancaster, ... Cell 158 (5), 1083-1093, 2014 | 187 | 2014 |
| An Evolutionarily Conserved Prion-like Element Converts Wild Fungi from Metabolic Specialists to Generalists DF Jarosz, AK Lancaster, J Brown, S Lindquist Cell 158 (5), 1072-1082, 2014 | 122 | 2014 |
| Saccharomyces cerevisiae DNA polymerase ε and polymerase σ interact physically and functionally, suggesting a role for polymerase ε in sister chromatid cohesion S Edwards, CM Li, DL Levy, J Brown, PM Snow, JL Campbell Molecular and cellular biology 23 (8), 2733-2748, 2003 | 113 | 2003 |
| Estrogen Receptor Antagonists Are Anti-Cryptococcal Agents That Directly Bind EF Hand Proteins and Synergize with Fluconazole In Vivo A Butts, K Koselny, Y Chabrier-Roselló, CP Semighini, JCS Brown, ... MBio 5 (1), e00765-13, 2014 | 97 | 2014 |
| A Major Role for Capsule-Independent Phagocytosis-Inhibitory Mechanisms in Mammalian Infection by Cryptococcus neoformans CD Chun, J Brown, HD Madhani Cell host & microbe 9 (3), 243-251, 2011 | 96 | 2011 |
| Unraveling the Biology of a Fungal Meningitis Pathogen Using Chemical Genetics JCS Brown, J Nelson, B VanderSluis, R Deshpande, A Butts, S Kagan, ... Cell 159 (5), 1168-1187, 2014 | 92 | 2014 |
| Mechanisms of Pulmonary Escape and Dissemination by Cryptococcus neoformans ST Denham, J Brown Journal of Fungi 4 (1), 25, 2018 | 76 | 2018 |
| High-throughput identification and rational design of synergistic small-molecule pairs for combating and bypassing antibiotic resistance MA Wambaugh, VPS Shakya, AJ Lewis, MA Mulvey, JCS Brown PLoS Biology 15 (6), e2001644, 2017 | 75 | 2017 |
| Phytotherapy as an alternative to conventional antimicrobials: combating microbial resistance SCMT Enioutina EY, Teng L, Fateeva TV, Brown JCS, Job KM, Bortnikova VV ... Expert Rev Clin Pharmacol, doi: 10.1080/17512433.2017.1371591, 2017 | 71 | 2017 |
| Regulated release of cryptococcal polysaccharide drives virulence and suppresses immune cell infiltration into the central nervous system ST Denham, S Verma, RC Reynolds, CL Worne, JM Daugherty, TE Lane, ... Infection and immunity 86 (3), e00662-17, 2018 | 68 | 2018 |
| Synergistic and antagonistic drug interactions in the treatment of systemic fungal infections MA Wambaugh, ST Denham, M Ayala, B Brammer, MA Stonhill, ... Elife 9, e54160, 2020 | 63 | 2020 |
| How environmental fungi cause a range of clinical outcomes in susceptible hosts ST Denham, MA Wambaugh, JCS Brown Journal of molecular biology 431 (16), 2982-3009, 2019 | 44 | 2019 |
| Cisplatin DNA cross-links do not inhibit S-phase and cause only a G2/M arrest in Saccharomyces cerevisiae KF Grossmann, JC Brown, RE Moses Mutation Research/DNA Repair 434 (1), 29-39, 1999 | 40 | 1999 |
| A dissemination-prone morphotype enhances extrapulmonary organ entry by Cryptococcus neoformans ST Denham, B Brammer, KY Chung, MA Wambaugh, JM Bednarek, ... Cell Host & Microbe 30 (10), 1382-1400. e8, 2022 | 39 | 2022 |
| Approaching the functional annotation of fungal virulence factors using cross-species genetic interaction profiling JCS Brown, HD Madhani PLoS genetics 8 (12), e1003168, 2012 | 14 | 2012 |
| antifungal pipeline: build it strong; build it better! JR Perfect, DJ Krysan, M Del Poeta, AM Selmecki, J Brown, LE Cowen Frontiers in Cellular and Infection Microbiology 12, 881272, 2022 | 7 | 2022 |
| Biology and Function of Exo-Polysaccharides from Human Fungal Pathogens KY Chung, JCS Brown Current Clinical Microbiology Reports 7 (1), 1-11, 2020 | 7 | 2020 |
| Distinct pathways of adaptive evolution in Cryptococcus neoformans reveal a mutation in adenylyl cyclase with trade-offs for pathogenicity ZA Hilbert, JM Bednarek, MJW Schwiesow, KY Chung, CT Moreau, ... Current Biology 33 (19), 4136-4149. e9, 2023 | 5 | 2023 |
