| GSDMD membrane pore formation constitutes the mechanism of pyroptotic cell death L Sborgi, S Rühl, E Mulvihill, J Pipercevic, R Heilig, H Stahlberg, ... The EMBO journal 35 (16), 1766-1778, 2016 | 1115 | 2016 |
| ESCRT-dependent membrane repair negatively regulates pyroptosis downstream of GSDMD activation S Rühl, K Shkarina, B Demarco, R Heilig, JC Santos, P Broz Science 362 (6417), 956-960, 2018 | 619 | 2018 |
| The Gasdermin‐D pore acts as a conduit for IL‐1β secretion in mice R Heilig, MS Dick, L Sborgi, E Meunier, S Hiller, P Broz European journal of immunology 48 (4), 584-592, 2018 | 391 | 2018 |
| Extrinsic and intrinsic apoptosis activate pannexin‐1 to drive NLRP 3 inflammasome assembly KW Chen, B Demarco, R Heilig, K Shkarina, A Boettcher, CJ Farady, ... The EMBO journal 38 (10), e101638, 2019 | 367 | 2019 |
| The inflammasome drives GSDMD-independent secondary pyroptosis and IL-1 release in the absence of caspase-1 protease activity KS Schneider, CJ Groß, RF Dreier, BS Saller, R Mishra, O Gorka, R Heilig, ... Cell reports 21 (13), 3846-3859, 2017 | 290 | 2017 |
| Human GBP1 binds LPS to initiate assembly of a caspase-4 activating platform on cytosolic bacteria JC Santos, D Boucher, LK Schneider, B Demarco, M Dilucca, K Shkarina, ... Nature communications 11 (1), 1-15, 2020 | 249 | 2020 |
| Function and mechanism of the pyrin inflammasome R Heilig, P Broz European journal of immunology 48 (2), 230-238, 2018 | 223 | 2018 |
| Stepwise Priming by Acidic pH and a High K+ Concentration Is Required for Efficient Uncoating of Influenza A Virus Cores after Penetration S Stauffer, Y Feng, F Nebioglu, R Heilig, P Picotti, A Helenius Journal of virology 88 (22), 13029-13046, 2014 | 185 | 2014 |
| RIPK1 activates distinct gasdermins in macrophages and neutrophils upon pathogen blockade of innate immune signalling K Chen, B Demarco, R Heilig, S Ramos, J Grayczyk, CA Assenmacher, ... bioRxiv, 2021 | 101 | 2021 |
| Caspase-1 cleaves Bid to release mitochondrial SMAC and drive secondary necrosis in the absence of GSDMD R Heilig, M Dilucca, D Boucher, KW Chen, D Hancz, B Demarco, ... Life science alliance 3 (6), 2020 | 87 | 2020 |
| Mobilizable Plasmids for Tunable Gene Expression in Francisella novicida M Brodmann, R Heilig, P Broz, M Basler Frontiers in cellular and infection microbiology 8, 284, 2018 | 8 | 2018 |
