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Leah B. Bushin
Leah B. Bushin
E-mailová adresa ověřena na: ucsd.edu
Název
Citace
Citace
Rok
Structure and biosynthesis of a macrocyclic peptide containing an unprecedented lysine-to-tryptophan crosslink
KR Schramma, LB Bushin, MR Seyedsayamdost
Nature chemistry 7 (5), 431-437, 2015
2432015
Discovery of a Cryptic Antifungal Compound from Streptomyces albus J1074 Using High-Throughput Elicitor Screens
F Xu, B Nazari, K Moon, LB Bushin, MR Seyedsayamdost
Journal of the American Chemical Society 139 (27), 9203-9212, 2017
1772017
A genetics-free method for high-throughput discovery of cryptic microbial metabolites
F Xu, Y Wu, C Zhang, KM Davis, K Moon, LB Bushin, ...
Nature chemical biology 15 (2), 161-168, 2019
1522019
Charting an unexplored streptococcal biosynthetic landscape reveals a unique peptide cyclization motif
LB Bushin, KA Clark, I Pelczer, MR Seyedsayamdost
Journal of the American Chemical Society 140 (50), 17674-17684, 2018
1012018
Discovery of scmR as a global regulator of secondary metabolism and virulence in Burkholderia thailandensis E264
D Mao, LB Bushin, K Moon, Y Wu, MR Seyedsayamdost
Proceedings of the National Academy of Sciences 114 (14), E2920-E2928, 2017
922017
Radical approach to enzymatic β-thioether bond formation
A Caruso, LB Bushin, KA Clark, RJ Martinie, MR Seyedsayamdost
Journal of the American Chemical Society 141 (2), 990-997, 2018
832018
Mapping the Trimethoprim-Induced Secondary Metabolome of Burkholderia thailandensis
BK Okada, Y Wu, D Mao, LB Bushin, MR Seyedsayamdost
ACS chemical biology 11 (8), 2124-2130, 2016
782016
Macrocyclization via an Arginine-Tyrosine Crosslink Broadens the Reaction Scope of Radical S-Adenosylmethionine Enzymes
A Caruso, RJ Martinie, LB Bushin, MR Seyedsayamdost
Journal of the American Chemical Society 141 (42), 16610-16614, 2019
772019
Acinetodin and Klebsidin, RNA Polymerase Targeting Lasso Peptides Produced by Human Isolates of Acinetobacter gyllenbergii and Klebsiella pneumoniae
M Metelev, A Arseniev, LB Bushin, K Kuznedelov, TO Artamonova, ...
ACS Chemical Biology 12 (3), 814-824, 2017
662017
Discovery and biosynthesis of streptosactin, a sactipeptide with an alternative topology encoded by commensal bacteria in the human microbiome
LB Bushin, BC Covington, BE Rued, MJ Federle, MR Seyedsayamdost
Journal of the American Chemical Society 142 (38), 16265-16275, 2020
642020
Total synthesis and stereochemical assignment of streptide
NA Isley, Y Endo, ZC Wu, BC Covington, LB Bushin, MR Seyedsayamdost, ...
Journal of the American Chemical Society 141 (43), 17361-17369, 2019
642019
Aliphatic ether bond formation expands the scope of radical SAM enzymes in natural product biosynthesis
KA Clark, LB Bushin, MR Seyedsayamdost
Journal of the American Chemical Society 141 (27), 10610-10615, 2019
612019
Quorum sensing in streptococcus mutans regulates production of tryglysin, a novel ras-ripp antimicrobial compound
BE Rued, BC Covington, LB Bushin, G Szewczyk, I Laczkovich, ...
MBio 12 (2), 10.1128/mbio. 02688-20, 2021
422021
RaS-RiPPs in streptococci and the human microbiome
KA Clark, LB Bushin, MR Seyedsayamdost
ACS bio & med Chem Au 2 (4), 328-339, 2022
292022
Bicyclostreptins are radical SAM enzyme-modified peptides with unique cyclization motifs
LB Bushin, BC Covington, KA Clark, A Caruso, MR Seyedsayamdost
Nature Chemical Biology 18 (10), 1135-1143, 2022
232022
Backbone-enabled peptide macrocyclization through late-stage palladium-catalyzed C–H activation
Z Bai, H Wang
Synlett 31 (03), 199-204, 2020
192020
Guidelines for determining the structures of radical SAM enzyme-catalyzed modifications in the biosynthesis of RiPP natural products
LB Bushin, MR Seyedsayamdost
Methods in Enzymology 606, 439-460, 2018
152018
Mapping the trimethoprim-induced secondary metabolome of Burkholderia thailandensis. ACS Chem Biol 11: 2124–2130
BK Okada, Y Wu, D Mao, LB Bushin, MR Seyedsayamdost
92016
Expanding the Landscape of Noncanonical Amino Acids in RiPP Biosynthesis
BA Johnson, KA Clark, LB Bushin, CN Spolar, MR Seyedsayamdost
Journal of the American Chemical Society 146 (6), 3805-3815, 2024
52024
Cryptic metabolites and method for activating silent biosynthetic gene clusters in diverse microorganisms
MR Seyedsayamdost, F Xu, WU Yihan, L Bushin, K Davis
US Patent 11,549,950, 2023
12023
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Články 1–20