The crucial role of methodology development in directed evolution of selective enzymes G Qu, A Li, CG Acevedo‐Rocha, Z Sun, MT Reetz Angewandte Chemie International Edition 59 (32), 13204-13231, 2020 | 405 | 2020 |
P450-catalyzed regio-and diastereoselective steroid hydroxylation: efficient directed evolution enabled by mutability landscaping CG Acevedo-Rocha, CG Gamble, R Lonsdale, A Li, N Nett, ... Acs Catalysis 8 (4), 3395-3410, 2018 | 153 | 2018 |
A redox-mediated Kemp eliminase Aitao Li, Binju Wang, Adriana Ilie, Kshatresh D. Dubey, Gert Bange, Ivan V ... Nature Communications 8, 14876, 2017 | 152* | 2017 |
Structure-guided triple-code saturation mutagenesis: efficient tuning of the stereoselectivity of an epoxide hydrolase Z Sun, R Lonsdale, L Wu, G Li, A Li, J Wang, J Zhou, MT Reetz ACS catalysis 6 (3), 1590-1597, 2016 | 128 | 2016 |
Regio‐and stereoselective steroid hydroxylation at C7 by cytochrome P450 monooxygenase mutants A Li, CG Acevedo‐Rocha, L D'Amore, J Chen, Y Peng, M Garcia‐Borràs, ... Angewandte Chemie 132 (30), 12599-12605, 2020 | 110 | 2020 |
Enantioselective trans-Dihydroxylation of Aryl Olefins by Cascade Biocatalysis with Recombinant Escherichia coli Coexpressing Monooxygenase and Epoxide … S Wu, Y Chen, Y Xu, A Li, Q Xu, A Glieder, Z Li ACS Catalysis 4 (2), 409-420, 2014 | 103 | 2014 |
Pyrococcus furiosus Argonaute-mediated nucleic acid detection R He, L Wang, F Wang, W Li, Y Liu, A Li, Y Wang, W Mao, C Zhai, L Ma Chemical communications 55 (88), 13219-13222, 2019 | 102 | 2019 |
Pervasive cooperative mutational effects on multiple catalytic enzyme traits emerge via long-range conformational dynamics CG Acevedo-Rocha, A Li, L D’Amore, S Hoebenreich, J Sanchis, ... Nature Communications 12 (1), 1621, 2021 | 94 | 2021 |
PfAgo-based detection of SARS-CoV-2 F Wang, J Yang, R He, X Yu, S Chen, Y Liu, L Wang, A Li, L Liu, C Zhai, ... Biosensors & bioelectronics 177, 112932, 2020 | 93 | 2020 |
Preparation of Structurally Diverse Chiral Alcohols by Engineering Ketoreductase CgKR1 GW Zheng, YY Liu, Q Chen, L Huang, HL Yu, WY Lou, CX Li, YP Bai, ... ACS Catalysis 7 (10), 7174-7181, 2017 | 90 | 2017 |
Whole‐cell‐catalyzed multiple regio‐and stereoselective functionalizations in cascade reactions enabled by directed evolution A Li, A Ilie, Z Sun, R Lonsdale, JH Xu, MT Reetz Angewandte Chemie 128 (39), 12205-12208, 2016 | 87 | 2016 |
Efficient production of biodiesel from waste grease: one-pot esterification and transesterification with tandem lipases J Yan, A Li, Y Xu, TPN Ngo, S Phua, Z Li Bioresource Technology 123, 332-337, 2012 | 81 | 2012 |
One-pot biocatalytic route from cycloalkanes to α,ω‐dicarboxylic acids by designed Escherichia coli consortia F Wang, J Zhao, Q Li, J Yang, R Li, J Min, X Yu, GW Zheng, HL Yu, C Zhai, ... Nature Communications 11 (1), 5035, 2020 | 80 | 2020 |
One-pot conversion of biomass-derived xylose to furfuralcohol by a chemo-enzymatic sequential acid-catalyzed dehydration and bioreduction Y He, Y Ding, C Ma, J Di, C Jiang, A Li Green Chemistry 19 (16), 3844-3850, 2017 | 80 | 2017 |
Enantioselective Hydrolysis of Racemic and Meso-Epoxides with Recombinant Escherichia coli Expressing Epoxide Hydrolase from Sphingomonas sp. HXN-200: Preparation of Epoxides … SK Wu, AT Li, Z Li ACS catalysis 3 (4), 752-759, 2013 | 78 | 2013 |
Bacterial cytochrome P450-catalyzed regio-and stereoselective steroid hydroxylation enabled by directed evolution and rational design X Zhang, Y Peng, J Zhao, Q Li, X Yu, CG Acevedo-Rocha, A Li Bioresources and Bioprocessing 7, 1-18, 2020 | 76 | 2020 |
Efficient transformation of grease to biodiesel using highly active and easily recyclable magnetic nanobiocatalyst aggregates TPN Ngo, A Li, KW Tiew, Z Li Bioresource technology 145, 233-239, 2013 | 76 | 2013 |
Chemo‐and regioselective dihydroxylation of benzene to hydroquinone enabled by engineered cytochrome P450 monooxygenase H Zhou, B Wang, F Wang, X Yu, L Ma, A Li, MT Reetz Angewandte Chemie 131 (3), 774-778, 2019 | 75 | 2019 |
Whole-cell based solvent-free system for one-pot production of biodiesel from waste grease A Li, TPN Ngo, J Yan, K Tian, Z Li Bioresource Technology 114, 725-729, 2012 | 57 | 2012 |
An Unusual (R)‐Selective Epoxide Hydrolase with High Activity for Facile Preparation of Enantiopure Glycidyl Ethers J Zhao, YY Chu, AT Li, X Ju, XD Kong, J Pan, Y Tang, JH Xu Advanced Synthesis & Catalysis 353 (9), 1510-1518, 2011 | 56 | 2011 |