| Altered function of the SCN1A voltage-gated sodium channel leads to γ-aminobutyric acid-ergic (GABAergic) interneuron abnormalities MS Martin, K Dutt, LA Papale, CM Dubé, SB Dutton, G de Haan, ... Journal of Biological Chemistry 285 (13), 9823-9834, 2010 | 265 | 2010 |
| The voltage-gated sodium channel Scn8a is a genetic modifier of severe myoclonic epilepsy of infancy MS Martin, B Tang, LA Papale, FH Yu, WA Catterall, A Escayg Human molecular genetics 16 (23), 2892-2899, 2007 | 262 | 2007 |
| Preferential inactivation of Scn1a in parvalbumin interneurons increases seizure susceptibility SB Dutton, CD Makinson, LA Papale, A Shankar, B Balakrishnan, ... Neurobiology of disease 49, 211-220, 2013 | 146 | 2013 |
| Heterozygous mutations of the voltage-gated sodium channel SCN8A are associated with spike-wave discharges and absence epilepsy in mice LA Papale, B Beyer, JM Jones, LM Sharkey, S Tufik, M Epstein, VA Letts, ... Human molecular genetics 18 (9), 1633-1641, 2009 | 146 | 2009 |
| A BAC transgenic mouse model reveals neuron subtype-specific effects of a Generalized Epilepsy with Febrile Seizures Plus (GEFS+) mutation B Tang, K Dutt, L Papale, R Rusconi, A Shankar, J Hunter, S Tufik, ... Neurobiology of disease 35 (1), 91-102, 2009 | 114 | 2009 |
| Sleep pattern in rats under different stress modalities LA Papale, ML Andersen, IB Antunes, TAF Alvarenga, S Tufik Brain research 1060 (1-2), 47-54, 2005 | 76 | 2005 |
| Altered sleep regulation in a mouse model of SCN1A‐derived genetic epilepsy with febrile seizures plus (GEFS+) LA Papale, CD Makinson, J Christopher Ehlen, S Tufik, MJ Decker, ... Epilepsia 54 (4), 625-634, 2013 | 65 | 2013 |
| Genome-wide alterations in hippocampal 5-hydroxymethylcytosine links plasticity genes to acute stress S Li, LA Papale, Q Zhang, A Madrid, L Chen, P Chopra, S Keleş, P Jin, ... Neurobiology of disease 86, 99-108, 2016 | 57 | 2016 |
| Early-life febrile seizures worsen adult phenotypes in Scn1a mutants SBB Dutton, K Dutt, LA Papale, S Helmers, AL Goldin, A Escayg Experimental neurology 293, 159-171, 2017 | 55 | 2017 |
| DNA hypomethylation in blood links B3GALT4 and ZADH2 to Alzheimer’s disease A Madrid, KJ Hogan, LA Papale, LR Clark, S Asthana, SC Johnson, ... Journal of Alzheimer's Disease 66 (3), 927-934, 2018 | 54 | 2018 |
| Influence of long-term food restriction on sleep pattern in male rats TAF Alvarenga, ML Andersen, LA Papale, IB Antunes, S Tufik Brain research 1057 (1-2), 49-56, 2005 | 53 | 2005 |
| Dysfunction of the Scn8a voltage-gated sodium channel alters sleep architecture, reduces diurnal corticosterone levels, and enhances spatial memory LA Papale, KN Paul, NT Sawyer, JR Manns, S Tufik, A Escayg Journal of Biological Chemistry 285 (22), 16553-16561, 2010 | 52 | 2010 |
| Genome-wide disruption of 5-hydroxymethylcytosine in a mouse model of autism LA Papale, Q Zhang, S Li, K Chen, S Keleş, RS Alisch Human molecular genetics 24 (24), 7121-7131, 2015 | 47 | 2015 |
| Early-life stress links 5-hydroxymethylcytosine to anxiety-related behaviors LA Papale, A Madrid, S Li, RS Alisch Epigenetics 12 (4), 264-276, 2017 | 46 | 2017 |
| Array-based assay detects genome-wide 5-mC and 5-hmC in the brains of humans, non-human primates, and mice P Chopra, LA Papale, ATJ White, A Hatch, RM Brown, MA Garthwaite, ... BMC genomics 15, 1-14, 2014 | 41 | 2014 |
| Differentially methylated genes in saliva are linked to childhood stress LA Papale, LJ Seltzer, A Madrid, SD Pollak, RS Alisch Scientific reports 8 (1), 10785, 2018 | 39 | 2018 |
| Hippocampal increase of 5-hmC in the glucocorticoid receptor gene following acute stress S Li, LA Papale, DB Kintner, G Sabat, GA Barrett-Wilt, P Cengiz, RS Alisch Behavioural brain research 286, 236-240, 2015 | 39 | 2015 |
| Glyoxalase 1 and its substrate methylglyoxal are novel regulators of seizure susceptibility MG Distler, N Gorfinkle, LA Papale, GE Wuenschell, J Termini, A Escayg, ... Epilepsia 54 (4), 649-657, 2013 | 39 | 2013 |
| Progesterone reduces erectile dysfunction in sleep-deprived spontaneously hypertensive rats ML Andersen, RCS Martins, TAF Alvarenga, IB Antunes, LA Papale, ... Reproductive Biology and Endocrinology 5, 1-12, 2007 | 35 | 2007 |
| New hope: the emerging role of 5-hydroxymethylcytosine in mental health and disease A Madrid, LA Papale, RS Alisch Epigenomics 8 (7), 981-991, 2016 | 32 | 2016 |
