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Autoantibodies neutralizing type I IFNs are present in~ 4% of uninfected individuals over 70 years old and account for~ 20% of COVID-19 deaths P Bastard, A Gervais, T Le Voyer, J Rosain, Q Philippot, J Manry, ... Science immunology 6 (62), eabl4340, 2021 | 543 | 2021 |
Primary B cell immunodeficiencies: comparisons and contrasts ME Conley, AK Dobbs, DM Farmer, S Kilic, K Paris, S Grigoriadou, ... Annual review of immunology 27 (1), 199-227, 2009 | 510 | 2009 |
X-linked recessive TLR7 deficiency in~ 1% of men under 60 years old with life-threatening COVID-19 T Asano, B Boisson, F Onodi, D Matuozzo, M Moncada-Velez, ... Science immunology 6 (62), eabl4348, 2021 | 388 | 2021 |
An immune-based biomarker signature is associated with mortality in COVID-19 patients MS Abers, OM Delmonte, EE Ricotta, J Fintzi, DL Fink, AAA de Jesus, ... JCI insight 6 (1), 2021 | 358 | 2021 |
Human HOIP and LUBAC deficiency underlies autoinflammation, immunodeficiency, amylopectinosis, and lymphangiectasia B Boisson, E Laplantine, K Dobbs, A Cobat, N Tarantino, M Hazen, ... Journal of Experimental Medicine 212 (6), 939-951, 2015 | 269 | 2015 |
Agammaglobulinemia and absent B lineage cells in a patient lacking the p85α subunit of PI3K ME Conley, AK Dobbs, AM Quintana, A Bosompem, YD Wang, ... Journal of Experimental Medicine 209 (3), 463-470, 2012 | 251 | 2012 |
Immunopathological signatures in multisystem inflammatory syndrome in children and pediatric COVID-19 K Sacco, R Castagnoli, S Vakkilainen, C Liu, OM Delmonte, C Oguz, ... Nature medicine 28 (5), 1050-1062, 2022 | 225 | 2022 |
Time-resolved systems immunology reveals a late juncture linked to fatal COVID-19 C Liu, AJ Martins, WW Lau, N Rachmaninoff, J Chen, L Imberti, ... Cell 184 (7), 1836-1857. e22, 2021 | 208 | 2021 |
Magnitude and dynamics of the T-cell response to SARS-CoV-2 infection at both individual and population levels TM Snyder, RM Gittelman, M Klinger, DH May, EJ Osborne, R Taniguchi, ... Frontiers in Immunology 15, 1488860, 2025 | 207 | 2025 |
Inherited DOCK2 deficiency in patients with early-onset invasive infections K Dobbs, C Domínguez Conde, SY Zhang, S Parolini, M Audry, J Chou, ... New England Journal of Medicine 372 (25), 2409-2422, 2015 | 196 | 2015 |
A large-scale database of T-cell receptor beta (TCRβ) sequences and binding associations from natural and synthetic exposure to SARS-CoV-2 S Nolan, M Vignali, M Klinger, JN Dines, IM Kaplan, E Svejnoha, T Craft, ... Research square, 2020 | 192 | 2020 |
Severe influenza pneumonitis in children with inherited TLR3 deficiency HK Lim, SXL Huang, J Chen, G Kerner, O Gilliaux, P Bastard, K Dobbs, ... Journal of Experimental Medicine 216 (9), 2038-2056, 2019 | 190 | 2019 |
Broad-spectrum antibodies against self-antigens and cytokines in RAG deficiency JE Walter, LB Rosen, K Csomos, JM Rosenberg, D Mathew, M Keszei, ... The Journal of clinical investigation 125 (11), 4135-4148, 2015 | 183 | 2015 |
Whole-exome sequencing identifies tetratricopeptide repeat domain 7A (TTC7A) mutations for combined immunodeficiency with intestinal atresias R Chen, S Giliani, G Lanzi, GI Mias, S Lonardi, K Dobbs, J Manis, H Im, ... Journal of allergy and clinical immunology 132 (3), 656-664. e17, 2013 | 168 | 2013 |
The risk of COVID-19 death is much greater and age dependent with type I IFN autoantibodies J Manry, P Bastard, A Gervais, T Le Voyer, J Rosain, Q Philippot, ... Proceedings of the National Academy of Sciences 119 (21), 2022 | 164 | 2022 |
A systematic analysis of recombination activity and genotype-phenotype correlation in human recombination-activating gene 1 deficiency YN Lee, F Frugoni, K Dobbs, JE Walter, S Giliani, AR Gennery, W Al-Herz, ... Journal of allergy and clinical immunology 133 (4), 1099-1108. e12, 2014 | 153 | 2014 |
Inborn errors of RNA lariat metabolism in humans with brainstem viral infection SY Zhang, NE Clark, CA Freije, E Pauwels, AJ Taggart, S Okada, ... Cell 172 (5), 952-965. e18, 2018 | 124 | 2018 |
T-cell defects in patients with ARPC1B germline mutations account for combined immunodeficiency I Brigida, M Zoccolillo, MP Cicalese, L Pfajfer, F Barzaghi, S Scala, ... Blood, The Journal of the American Society of Hematology 132 (22), 2362-2374, 2018 | 121 | 2018 |
Human SNORA31 variations impair cortical neuron-intrinsic immunity to HSV-1 and underlie herpes simplex encephalitis FG Lafaille, O Harschnitz, YS Lee, P Zhang, ML Hasek, G Kerner, Y Itan, ... Nature medicine 25 (12), 1873-1884, 2019 | 118 | 2019 |