| Antioxidants accelerate lung cancer progression in mice VI Sayin, MX Ibrahim, E Larsson, JA Nilsson, P Lindahl, MO Bergo Science translational medicine 6 (221), 221ra15-221ra15, 2014 | 960 | 2014 |
| Antioxidants can increase melanoma metastasis in mice K Le Gal, MX Ibrahim, C Wiel, VI Sayin, MK Akula, C Karlsson, MG Dalin, ... Science translational medicine 7 (308), 308re8-308re8, 2015 | 702 | 2015 |
| Keap1 loss promotes Kras-driven lung cancer and results in dependence on glutaminolysis R Romero, VI Sayin, SM Davidson, MR Bauer, SX Singh, SE LeBoeuf, ... Nature medicine 23 (11), 1362-1368, 2017 | 607 | 2017 |
| Nrf2 activation promotes lung cancer metastasis by inhibiting the degradation of Bach1 L Lignitto, SE LeBoeuf, H Homer, S Jiang, M Askenazi, TR Karakousi, ... Cell 178 (2), 316-329. e18, 2019 | 486 | 2019 |
| BACH1 stabilization by antioxidants stimulates lung cancer metastasis C Wiel, K Le Gal, MX Ibrahim, CA Jahangir, M Kashif, H Yao, DV Ziegler, ... Cell 178 (2), 330-345. e22, 2019 | 485 | 2019 |
| Activation of the NRF2 antioxidant program generates an imbalance in central carbon metabolism in cancer VI Sayin, SE LeBoeuf, SX Singh, SM Davidson, D Biancur, BS Guzelhan, ... elife 6, e28083, 2017 | 217 | 2017 |
| Targeting isoprenylcysteine methylation ameliorates disease in a mouse model of progeria MX Ibrahim, VI Sayin, MK Akula, M Liu, LG Fong, SG Young, MO Bergo Science 340 (6138), 1330-1333, 2013 | 138 | 2013 |
| Activation of oxidative stress response in cancer generates a druggable dependency on exogenous non-essential amino acids SE LeBoeuf, WL Wu, TR Karakousi, B Karadal, SRE Jackson, ... Cell metabolism 31 (2), 339-350. e4, 2020 | 129 | 2020 |
| Oncogene-induced senescence underlies the mutual exclusive nature of oncogenic KRAS and BRAF J Cisowski, VI Sayin, M Liu, C Karlsson, MO Bergo Oncogene 35 (10), 1328-1333, 2016 | 116 | 2016 |
| Cellular redox homeostasis K Le Gal, EE Schmidt, VI Sayin Antioxidants 10 (9), 1377, 2021 | 97 | 2021 |
| TrxR1, Gsr, and oxidative stress determine hepatocellular carcinoma malignancy MR McLoughlin, DJ Orlicky, JR Prigge, P Krishna, EA Talago, IR Cavigli, ... Proceedings of the National Academy of Sciences 116 (23), 11408-11417, 2019 | 78 | 2019 |
| Protein prenylation restrains innate immunity by inhibiting Rac1 effector interactions MK Akula, MX Ibrahim, EG Ivarsson, OM Khan, IT Kumar, M Erlandsson, ... Nature communications 10 (1), 3975, 2019 | 73 | 2019 |
| Pan-cancer transcriptomic analysis associates long non-coding RNAs with key mutational driver events A Ashouri, VI Sayin, J Van den Eynden, SX Singh, T Papagiannakopoulos, ... Nature communications 7 (1), 13197, 2016 | 60 | 2016 |
| The pleiotropic functions of reactive oxygen species in cancer K Wu, AE El Zowalaty, VI Sayin, T Papagiannakopoulos Nature Cancer 5 (3), 384-399, 2024 | 57 | 2024 |
| Loss of one copy of Zfp148 reduces lesional macrophage proliferation and atherosclerosis in mice by activating p53 VI Sayin, OM Khan, LE Pehlivanoglu, A Staffas, MX Ibrahim, A Asplund, ... Circulation research 115 (9), 781-789, 2014 | 52 | 2014 |
| Excessive copper impairs intrahepatocyte trafficking and secretion of selenoprotein P M Schwarz, CE Meyer, A Löser, K Lossow, J Hackler, C Ott, S Jäger, ... Nature Communications 14 (1), 3479, 2023 | 25 | 2023 |
| KRAS Mutations Impact Clinical Outcome in Metastatic Non-Small Cell Lung Cancer EA Eklund, C Wiel, H Fagman, LM Akyürek, S Raghavan, J Nyman, ... Cancers 14 (9), 2063, 2022 | 23 | 2022 |
| Application of CRISPR-mediated genome engineering in cancer research VI Sayin, T Papagiannakopoulos Cancer letters 387, 10-17, 2017 | 23 | 2017 |
| Zfp148 deficiency causes lung maturation defects and lethality in newborn mice that are rescued by deletion of p53 or antioxidant treatment VI Sayin, A Nilton, MX Ibrahim, P Ågren, E Larsson, MM Petit, LM Hultén, ... PloS one 8 (2), e55720, 2013 | 23 | 2013 |
| Glutamine antagonist DRP-104 suppresses tumor growth and enhances response to checkpoint blockade in KEAP1 mutant lung cancer R Pillai, SE LeBoeuf, Y Hao, C New, JLE Blum, A Rashidfarrokhi, ... Science advances 10 (13), eadm9859, 2024 | 22 | 2024 |
Martin O. BergoDept. Biosciences and Nutrition, Karolinska InstitutetE-mailová adresa ověřena na: ki.se